dotriacontanedioic acid dimethyl ester | 14606-66-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: dotriacontanedioic acid dimethyl ester
• 英文别名: Dimethyl dotriacontane-dioate；dimethyl dotriacontanedioate
• CAS: 14606-66-7
• 化学式: C₃₄H₆₆O₄
• 分子量: 538.896
• InChiKey: OZEZPSMBCHDPBL-UHFFFAOYSA-N

物化性质

• 沸点：
  522.2±18.0 °C(Predicted)
• 密度：
  0.903±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  14.9
• 重原子数：
  38
• 可旋转键数：
  33
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dotriacontanedioic acid dimethyl ester 在 吡啶 、 sodium hydroxide 、 草酰氯 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 24.0h， 生成
  参考文献：
  名称：

  Synthesis of Ceramide Mimics with a Pseudo Cyclic Framework

  摘要：

  我们设计并合成了具有伪环框架的神经酰胺类似物，这些类似物可以转化为“二聚体”鞘磷脂和糖神经鞰脂，作为人工筏潜在的组成部分。这些分子的特点是具有（i）两个亲水性头部基团，（ii）共价连接的碳氢链，以及（iii）两个未固定的烷基链。神经酰胺类似物的自组装形成纳米棒的过程将简要讨论。

  DOI：

  10.1055/s-2003-42094
• 作为产物：
  描述：

  methyl 11-oxoundecanoate 在 铂 氢气 、 potassium 2-methylbutan-2-olate 作用下， 以 1,4-二氧六环 为溶剂， 反应 0.25h， 生成 dotriacontanedioic acid dimethyl ester
  参考文献：
  名称：

  Synthesis of new bifluorophoric probes adapted to studies of donor-donor electronic energy transfer in lipid systems

  摘要：

  A series of bifluorophoric fluorescent probes with identical pairs of chromophores have been synthesized. The fluorophores are 9-anthryl, 3-perylenyl and rhodamine 101, and they are separated by a long rigid (bisteroid) or flexible (dotriacontane) diol spacer. The probes are designed for studies of intra- and intermolecular electronic energy transfer in lipid systems such as model and biological membranes. They are shown to incorporate in phosphatidylcholine vesicles with an hitherto unknown orientation.

  DOI：

  10.1016/0009-3084(96)02537-6

文献信息

• Chain Multiplication of Fatty Acids to Precise Telechelic Polyethylene
  作者：Timo Witt、Manuel Häußler、Stefanie Kulpa、Stefan Mecking

  DOI：10.1002/anie.201702796

  日期：2017.6.19

  double bond of the α,ω‐dicarboxylic fatty acid self‐metathesis products is shifted selectively to the statistically much‐disfavored α,β‐position in a catalytic dynamic isomerizing crystallization approach. “Chain doubling” by a subsequent catalytic olefin metathesis step, which overcomes the low reactivity of this substrates by using waste internal olefins as recyclable co‐reagents, yields ultra‐long‐chain

  从常见的单不饱和脂肪酸开始，揭示了一种策略，该策略通过两个可扩展的催化步骤序列提供超长的脂肪族α，ω-双官能结构单元，实际上使起始原料的链长增加了一倍。在催化动态异构化结晶方法中，α，ω-二羧酸脂肪酸自复分解产物的中心双键选择性地转移到统计学上不利的α，β-位置。通过随后的催化烯烃复分解步骤实现“链加倍”，该步骤通过使用废弃的内部烯烃作为可回收的共试剂克服了这种底物的低反应性，从而产生了具有精确链长的超长链α，ω-双官能结构单元，如C 48所示链。这些结构的独特性体现在由这些遥螯单体产生的脂肪族聚酯的无与伦比的熔点（T m = 120°C），以及它们自组装成聚乙烯类单晶的过程。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• ——
  作者：L. B.-Å. Johansson、S. V. Kalinin、K. A. Filatova、Jul. G. Molotkovsky

  DOI：10.1023/a:1022238721223

  日期：——

  Three fluorescent probes were synthesized for studying the excitation energy migration between two identical fluorophores. Each probe has two identical fluorescent groups (dansyl, 7-nitrobenzo-2-oxa-1,3diazole-4-yl, or fluoresceinyl) linked by the rigid bis-(8-aminooctyl)amide of 4,4'-biphenyldicarbonic acid or flexible dotriacontanedioic acid spacer, which enables the intramolecular energy migration through the distance of 3.2-3.5 nm.
• Buchta,E.; Huhn,C., Justus Liebigs Annalen der Chemie, 1966, vol. 695, p. 42 - 48
  作者：Buchta,E.、Huhn,C.

  DOI：——

  日期：——