3-(p-Methylphenyl)-4,11-dihydroanthro<2,3-b>furan

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并呋喃类
• 英文名称: 3-(p-Methylphenyl)-4,11-dihydroanthro<2,3-b>furan
• 英文别名: 3-(4-Methylphenyl)-4,11-dihydronaphtho[2,3-f][1]benzofuran
• 化学式: C₂₃H₁₈O
• 分子量: 310.395
• InChiKey: AQDFKRLVQJNDNR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  13.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-(4-MeC6H4)-4-trimethylsilyl-furan 在 四(三苯基膦)钯 2,3-di(bromomethyl)naphthalene 、 三氯化硼 、 sodium carbonate 作用下， 生成 4,4'-Bis(p-methylphenyl)-3,3'-bifuran 、 3-(p-Methylphenyl)-4,11-dihydroanthro<2,3-b>furan
  参考文献：
  名称：

  Regiospecific synthesis of furan-3,4-diyl oligomers via palladium-catalyzed self-coupling of organoboroxines

  摘要：

  The palladium-catalyzed reaction of organoboroxines 2 and o-bis(bromomethyl)arenes 1 produced regiospecifically the cross-coupled products 3 and the corresponding dimeric bifurans 4. This method has been successfully applied to the synthesis of symmetrical, as well as unsymmetrical furan-3,4-diyl dimers, trimers, and tetramers. A furan-3,4-diyl octamer was also obtained by utilizing this method.

  DOI：

  10.1021/jo00080a009

文献信息

• Regiospecific synthesis of furan-3,4-diyl oligomers via palladium-catalyzed self-coupling of organoboroxines
  作者：Zhi Zhong Song、Henry N. C. Wong

  DOI：10.1021/jo00080a009

  日期：1994.1

  The palladium-catalyzed reaction of organoboroxines 2 and o-bis(bromomethyl)arenes 1 produced regiospecifically the cross-coupled products 3 and the corresponding dimeric bifurans 4. This method has been successfully applied to the synthesis of symmetrical, as well as unsymmetrical furan-3,4-diyl dimers, trimers, and tetramers. A furan-3,4-diyl octamer was also obtained by utilizing this method.