Substitution of the Benzotriazolyl Group inN-(α-Amidoalkyl)benzotriazoles andN-(α-Sulfonamidoalkyl)benzotriazoles with Allylsamarium Bromide
摘要:
The nucleophilic substitution of the benzotriazolyl group in the N-(alpha-benzotriazol-1-ylalkyl)amides and N-(alpha-benzotriazol-1-ylalkyl) sulfonamides with allylsamarium bromide was investigated, and the corresponding homoallylamides or homoallylsulfonamides were obtained in good to excellent yields.
N-(alpha-Benzotriazol-1-ylalkyl)sulfonamides, readily available from benzotriazole, an aldehyde and a sulfonamide, are converted into the corresponding N-(alpha-cyanoalkyl)sulfonamides in good yields by treatment with potassium cyanide.
Elimination of benzotriazolyl group in N-(α-benzotriazol-1-ylalkyl)amides and N-(α-benzotriazol-1-ylalkyl)sulfonamides: their self-coupling and cross-coupling reactions with carbonyl compounds
作者:Xiaoxia Wang、Yongjun Liu、Yongmin Zhang
DOI:10.1016/j.tet.2003.08.039
日期:2003.10
The elimination of benzotriazolyl group from N-(α-benzotriazol-1-ylalkyl)amides and N-(α-benzotriazol-1-ylalkyl)sulfonamides are readily realized with samariumdiiodide as a reducing agent. The resulting intermediates undergo a dimerization or cross-coupling reaction with carbonylcompounds, thus affording the corresponding dimers or α-hydroxyalkylated sulfonamides in moderate yields.
Substitution of the Benzotriazolyl Group in<b><i>N</i></b>-(α-Amidoalkyl)benzotriazoles and<b><i>N</i></b>-(α-Sulfonamidoalkyl)benzotriazoles with Allylsamarium Bromide
作者:Xiaoxia Wang、Jian Li、Yongmin Zhang
DOI:10.1081/scc-120024744
日期:2003.10
The nucleophilic substitution of the benzotriazolyl group in the N-(alpha-benzotriazol-1-ylalkyl)amides and N-(alpha-benzotriazol-1-ylalkyl) sulfonamides with allylsamarium bromide was investigated, and the corresponding homoallylamides or homoallylsulfonamides were obtained in good to excellent yields.
作者:Alan R. Katritzky、Daniela C. Oniciu、Ion Ghiviriga
DOI:10.1080/00397919708004211
日期:1997.3
N-(alpha-Benzotriazol-1-ylalkyl)sulfonamides, readily available from benzotriazole, an aldehyde and a sulfonamide, are converted into the corresponding N-(alpha-cyanoalkyl)sulfonamides in good yields by treatment with potassium cyanide.