N-Phenyl-2-[(5-phenyl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide | 88743-62-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-Phenyl-2-[(5-phenyl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide
• CAS: 88743-62-8
• 化学式: C₁₇H₁₆N₄OS
• 分子量: 324.406
• InChiKey: XKFQWEKDASGWQQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  96
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-(5-phenyl-1,2,4-triazol-3-ylthio)propanoic acid 在 乙酸酐 作用下， 反应 1.0h， 生成 N-Phenyl-2-[(5-phenyl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide
  参考文献：
  名称：

  Ali, Mohamed I.; Soliman, Adly A.-W., Journal fur praktische Chemie (Leipzig 1954), 1983, vol. 325, # 5, p. 869 - 875

  摘要：

  DOI：

文献信息

• COMPOSITIONS FOR INHIBITION OF INSECT SENSING
  申请人：Zwiebel Laurence

  公开号：US20140242135A1

  公开（公告）日：2014-08-28

  In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitos. Method of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  在一个方面，本发明涉及昆虫嗅觉受体的化学调节剂。具体地，提供了可以抑制空气传播昆虫（例如蚊子）的感觉（例如宿主定位）功能的化合物和组合物。还提供了使用这些剂的方法以及包含它们的文章。本摘要旨在作为搜索特定领域的扫描工具，不限制本发明。
• Compositions for inhibition of insect sensing
  申请人：Vanderbilt University

  公开号：US10188105B2

  公开（公告）日：2019-01-29

  In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitoes. Method of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  一方面，本发明涉及昆虫嗅觉受体的化学调节剂。特别是，本发明提供了可抑制蚊子等空气传播昆虫的感官（如宿主靶向）功能的化合物和组合物。此外，还提供了使用此类制剂的方法以及含有此类制剂的物品。本摘要旨在作为一种扫描工具，用于特定技术领域的搜索，而非对本发明的限制。
• ALI, MOHAMED, I.;SOLIMAN, ADLY, A. -W., J. PRAKT. CHEM., 1983, 325, N 5, 869-875
  作者：ALI, MOHAMED, I.、SOLIMAN, ADLY, A. -W.

  DOI：——

  日期：——
• COMPOSITION FOR INHIBITION OF INSECT SENSING
  申请人：Vanderbilt University

  公开号：EP2704575B1

  公开（公告）日：2020-06-03
• Compositions for Inhibition of Insect Sensing
  申请人：Vanderbilt University

  公开号：US20170208809A1

  公开（公告）日：2017-07-27

  In one aspect, the invention relates to chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit sensory (e.g., host targeting) functions in airborne insects such as mosquitoes. Method of employing such agents, and articles incorporating the same, are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.