di(2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl) 3,3'-(1H,1'H-[2,2'-biimidazole]-1,1'-diyl)dipropionate | 1373122-36-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: di(2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl) 3,3'-(1H,1'H-[2,2'-biimidazole]-1,1'-diyl)dipropionate
• CAS: 1373122-36-1
• 化学式: C₅₀H₉₀N₄O₂₂
• 分子量: 1099.28
• InChiKey: MGGFQNKLPXQNPN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.17
• 重原子数：
  76.0
• 可旋转键数：
  61.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  254.38
• 氢给体数：
  0.0
• 氢受体数：
  26.0

反应信息

• 作为反应物：
  描述：

  di(2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl) 3,3'-(1H,1'H-[2,2'-biimidazole]-1,1'-diyl)dipropionate 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 氯仿 为溶剂， 反应 2.0h， 以65.4%的产率得到2-[2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 3-[5-bromo-2-[5-bromo-1-[3-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-3-oxopropyl]imidazol-2-yl]imidazol-1-yl]propanoate
  参考文献：
  名称：

  2,2′-Biimidazole-Based Conjugated Polymers as a Novel Fluorescent Sensing Platform for Pyrophosphate Anion

  摘要：

  Three novel conjugated polymers based on 2,2'-biimidazole have been successfully designed and synthesized through the Suzuki coupling reactions, and their fluorescence sensing ability to metal ions and anions was investigated. The emission of the two polymers with hydrophilic side chains can be efficiently quenched by Cu2+ through a photoinduced electron transfer process. Moreover, the polymer Cu2+ complexes exhibit excellent "turn on" sensing properties for detection of pyrophosphate (PP anion. These complex sensors possess high selectivity avoiding the interference from other anions, very fast response (less than 3 min) to PPi, and the detection limit of about 0.17 ppm. In addition, the linear detection range of PPi can be tuned conveniently by changing the amount of Cu2+ ions. Thus, the conjugated polymers can be used as a novel fluorescent sensing platform, and this work provides a new strategy for the development of PPi sensors.

  DOI：

  10.1021/ma300361t
• 作为产物：
  描述：

  联咪唑 、 methoxy PEG(350) monoacrylate 在 sodium hydroxide 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 以98.7%的产率得到di(2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl) 3,3'-(1H,1'H-[2,2'-biimidazole]-1,1'-diyl)dipropionate
  参考文献：
  名称：

  2,2′-Biimidazole-Based Conjugated Polymers as a Novel Fluorescent Sensing Platform for Pyrophosphate Anion

  摘要：

  Three novel conjugated polymers based on 2,2'-biimidazole have been successfully designed and synthesized through the Suzuki coupling reactions, and their fluorescence sensing ability to metal ions and anions was investigated. The emission of the two polymers with hydrophilic side chains can be efficiently quenched by Cu2+ through a photoinduced electron transfer process. Moreover, the polymer Cu2+ complexes exhibit excellent "turn on" sensing properties for detection of pyrophosphate (PP anion. These complex sensors possess high selectivity avoiding the interference from other anions, very fast response (less than 3 min) to PPi, and the detection limit of about 0.17 ppm. In addition, the linear detection range of PPi can be tuned conveniently by changing the amount of Cu2+ ions. Thus, the conjugated polymers can be used as a novel fluorescent sensing platform, and this work provides a new strategy for the development of PPi sensors.

  DOI：

  10.1021/ma300361t