2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-formyl-3-pyridinyl]-N,2-dimethylpropanamide | 1301660-56-9

分子结构分类

有机化合物 - 有机杂环化合物 - 吡啶及其衍生物

中文名称

——

中文别名

——

英文名称

2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-formyl-3-pyridinyl]-N,2-dimethylpropanamide

英文别名

2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-formylpyridin-3-yl]-N,2-dimethylpropanamide

2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-formyl-3-pyridinyl]-N,2-dimethylpropanamide化学式

CAS

1301660-56-9

化学式

C₂₆H₂₁F₇N₂O₂

mdl

——

分子量

526.454

InChiKey

VDZXNPOPSOTKEY-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

6.4
重原子数：

37
可旋转键数：

5
环数：

3.0
sp3杂化的碳原子比例：

0.27
拓扑面积：

50.3
氢给体数：

0
氢受体数：

10

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-ethenyl-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-N,2-dimethylpropanamide	1301660-54-7	C₂₇H₂₃F₇N₂O	524.481
——	2-(3,5-bis-trifluoromethylphenyl)-N-[6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-N-methyl isobutyramide	825643-73-0	C₂₅H₂₀ClF₇N₂O	532.888

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	methyl 5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}-(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinecarboxylate	1301660-71-8	C₂₇H₂₃F₇N₂O₃	556.48
——	ethyl 3-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-2-propenoate	1301660-58-1	C₃₀H₂₇F₇N₂O₃	596.545
——	ethyl 3-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}-(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-3-oxopropanoate	1301660-72-9	C₃₀H₂₇F₇N₂O₄	612.544
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-(5-oxo-3-pyrrolidinyl)-3-pyridinyl]-N,2-dimethylpropanamide	1301659-84-6	C₂₉H₂₆F₇N₃O₂	581.533
——	ethyl 3-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-4-nitrobutanoate	1301660-61-6	C₃₁H₃₀F₇N₃O₅	657.585
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[4-(hydroxymethyl)-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	——	C₃₀H₂₈F₇N₃O₃	611.559
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[4-(hydroxymethyl)-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301659-93-7	C₃₀H₂₈F₇N₃O₃	611.559
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-(2,2-dimethyl-5-oxo-3-pyrrolidinyl)-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-N,2-dimethylpropanamide	1301660-34-3	C₃₁H₃₀F₇N₃O₂	609.587
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-(2,2-dimethyl-5-oxo-3-pyrrolidinyl)-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-N,2-dimethylpropanamide	1301660-36-5	C₃₁H₃₀F₇N₃O₂	609.587
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-[6-(2,2-dimethyl-5-oxo-3-pyrrolidinyl)-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-N,2-dimethylpropanamide	1301660-38-7	C₃₁H₃₀F₇N₃O₂	609.587
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[2-(hydroxymethyl)-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-15-0	C₃₀H₂₈F₇N₃O₃	611.559
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[2-(hydroxymethyl)-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-12-7	C₃₀H₂₈F₇N₃O₃	611.559
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[2-(hydroxymethyl)-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-13-8	C₃₀H₂₈F₇N₃O₃	611.559
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[3-(hydroxymethyl)-5-oxo-2-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-04-7	C₃₀H₂₈F₇N₃O₃	611.559
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[3-(hydroxymethyl)-5-oxo-2-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-03-6	C₃₀H₂₈F₇N₃O₃	611.559
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[4-(hydroxymethyl)-4-methyl-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-52-5	C₃₁H₃₀F₇N₃O₃	625.586
——	dimethyl {1-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-2-nitroethyl}propanedioate	1301661-17-5	C₃₂H₃₀F₇N₃O₇	701.595
——	N-[6-[4,4-bis(hydroxymethyl)-5-oxo-3-pyrrolidinyl]-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide	1301660-43-4	C₃₁H₃₀F₇N₃O₄	641.586
——	N-[6-(2-acetyl-5-oxo-3-pyrrolidinyl)-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide	1301661-12-0	C₃₁H₂₈F₇N₃O₃	623.57
——	1,1-dimethylethyl 4-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxylate	1301660-62-7	C₃₄H₃₄F₇N₃O₄	681.65
——	ethyl 3-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-4-methyl-4-nitropentanoate	1301660-88-7	C₃₃H₃₄F₇N₃O₅	685.639
——	3-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-5-oxoproline	1301660-82-1	C₃₀H₂₆F₇N₃O₄	625.543
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[2-(hydroxymethyl)-1-methyl-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-30-9	C₃₁H₃₀F₇N₃O₃	625.586
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[2-(1-hydroxyethyl)-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-47-8	C₃₁H₃₀F₇N₃O₃	625.586
——	methyl 4-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-2-oxo-3-pyrrolidinecarboxylate	1301660-66-1	C₃₁H₂₈F₇N₃O₄	639.57
——	N-[6-[2,2-bis(hydroxymethyl)-5-oxo-3-pyrrolidinyl]-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide	1301660-20-7	C₃₁H₃₀F₇N₃O₄	641.586
——	N-[6-[(3S)-2,2-bis(hydroxymethyl)-5-oxopyrrolidin-3-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide	——	C₃₁H₃₀F₇N₃O₄	641.586
——	N-[6-[2,2-bis(hydroxymethyl)-5-oxo-3-pyrrolidinyl]-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide	1301660-23-0	C₃₁H₃₀F₇N₃O₄	641.586
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[4-(1-hydroxy-1-methylethyl)-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-51-4	C₃₂H₃₂F₇N₃O₃	639.613
——	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[4-(hydroxymethyl)-2,2-dimethyl-5-oxo-3-pyrrolidinyl]-3-pyridinyl}-N,2-dimethylpropanamide	1301660-39-8	C₃₂H₃₂F₇N₃O₃	639.613