octacosanedioic acid | 5632-97-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: octacosanedioic acid
• 英文别名: Hexakosan-1,26-dicarbonsaeure；Octacosandisaeure
• CAS: 5632-97-3
• 化学式: C₂₈H₅₄O₄
• 分子量: 454.734
• InChiKey: WHTKRYWWSTYDNH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.9
• 重原子数：
  32
• 可旋转键数：
  27
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2917190090

反应信息

• 作为反应物：
  描述：

  octacosanedioic acid 在 氯化亚砜 作用下， 以 苯 为溶剂， 反应 6.0h， 生成 1,28-Bis-dibenzo[b,f]azepin-5-yl-octacosane-1,28-dione
  参考文献：
  名称：

  Intramolecular end-to-end reactions of photoactive terminal groups linked by polymethylene chains

  摘要：

  DOI：

  10.1021/ja00209a032
• 作为产物：
  描述：

  1,16-hexadecanedioyl dichloride 在 盐酸 、 氢氧化钾 、 sodium hydroxide 、 一水合肼 、 三乙胺 作用下， 以 乙醇 为溶剂， 反应 24.0h， 生成 octacosanedioic acid
  参考文献：
  名称：

  Intramolecular end-to-end reactions of photoactive terminal groups linked by polymethylene chains

  摘要：

  DOI：

  10.1021/ja00209a032

文献信息

• THERMAL ENERGY STORAGE AND TEMPERATURE STABILIZATION PHASE CHANGE MATERIALS COMPRISING ALKANOLAMIDES AND DIESTERS AND METHODS FOR MAKING AND USING THEM
  申请人：Entropy Solutions Inc.

  公开号：US20170044414A1

  公开（公告）日：2017-02-16

  This invention generally relates to thermoregulation and temperature stabilization, thermal protection and insulation, and nucleating agents. In particular, in alternative embodiments, provided are organic phase change materials comprising diesters and alkanolamides. In alternative embodiments, provided are Phase Change Material (PCMs) compositions comprising diesters and alkanolamides, and methods for making and using them. In alternative embodiments, the Phase Change Material (PCMs) compositions are used for thermal energy management, including energy storage and/or temperature stabilization, in various applications such as building, automotive, packaging, garment and footwear, textiles, fabrics, synthetic fibers, foods, microcapsules and other energy storage systems.

  这项发明通常涉及热调节和温度稳定、热保护和隔热以及成核剂。特别是，在替代实施方案中，提供了包括二酯和脂肪醇胺的有机相变材料。在替代实施方案中，提供了包括二酯和脂肪醇胺的相变材料（PCM）组合物，并提供了制备和使用它们的方法。在替代实施方案中，相变材料（PCM）组合物用于热能管理，包括在建筑、汽车、包装、服装和鞋类、纺织品、织物、合成纤维、食品、微胶囊和其他能量存储系统等各种应用中的能量存储和/或温度稳定。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• Optical resolution for producing optically active alcohol
  申请人：The Nisshin Oil Mills, Ltd.

  公开号：EP0709465A2

  公开（公告）日：1996-05-01

  A process for producing an optically active alcohol comprising carrying out interesterification between a racemic alcohol and an ester selected from the group consisting of (a) a diester between a lower monohydric alcohol and a saturated dicarboxylic acid having 14 or more carbon atoms, (b) a triglyceride of a saturated fatty acid having 16 or more carbon atoms, and (c) a monoester between a lower monohydric alcohol and a saturated fatty acid having 18 or more carbon atoms in the presence of lipase, preferably heat-resistant lipase, and in the presence or absence of a solvent, preferably in the absence of a solvent, under a substantially water-free condition, separating an optically active alcohol rich in either one of R- and S-forms from the reaction mixture, and adding an optically inactive non-racemic alcohol to the residue of the previous step to carry out interesterification under the same conditions as in the previous reaction to separate the other enantiomer. According to the present invention a racemic alcohol can easily be resolved into each enantiomer with high purity in good yield.

  一种生产光学活性醇的工艺，包括在脂肪酶存在下，在外消旋醇和选自以下组别的酯 之间进行酯化反应：(a)低级一元醇与具有 14 个或更多碳原子的饱和二羧酸之间的二酯；(b)具有 16 个或更多碳原子的饱和脂肪酸的甘油三酯；(c)低级一元醇与具有 18 个或更多碳原子的饱和脂肪酸之间的单酯、在有或无溶剂（最好是无溶剂）的条件下，在基本上无水的条件下，从反应混合物中分离出富含 R 型和 S 型中任一型的光学活性醇，并将光学不活泼的非外消旋醇加入到上一步的残留物中，在与上一步反应相同的条件下进行酯交换反应，以分离出另一种对映体。 根据本发明，外消旋醇可以很容易地以高纯度和高产率分离成每种对映体。
• Process for producing optically active alcohol containing phenyl group
  申请人：The Nisshin Oil Mills, Ltd.

  公开号：EP0714984A2

  公开（公告）日：1996-06-05

  A process for producing an optically active alcohol having a phenyl group is disclosed, comprising the step of carrying out interesterification between (a) a monoester between a racemic alcohol having a phenyl group and a fatty acid or a diester between a racemic alcohol having a phenyl group and a dibasic acid and (b) an optically inactive non-racemic alcohol having 16 or more carbon atoms in the presence of heat-resistant lipase and in the absence of a solvent under a substantially water-free condition at a temperature of not lower than 81°C under atmospheric pressure or reduced pressure and the step of separating an optically active alcohol having a phenyl group rich in either one of R- and S-forms from the reaction mixture. Use of heat-resistant lipase makes it possible to use high-melting point materials without using any solvent therefor and to perform interesterification at a high temperature thereby completing the reaction in a reduced time. Further, use of a high-melting point and high-boiling point starting material makes it possible to separate an optically active alcohol from the reaction mixture with high purity in high yield by means of a simple purification step taking advantage of a difference in physical properties. In particular, where the interesterification is carried out under reduced pressure, separation and purification of an optically active alcohol can be conducted simultaneously with the reaction progress.

  本发明公开了一种具有苯基的光学活性醇的生产工艺、包括以下步骤：在耐热脂肪酶的存在下，在无溶剂的条件下，在不低于 81℃的温度下，在大气压或减压条件下，将(a)具有苯基的外消旋醇与脂肪酸之间的单酯或具有苯基的外消旋醇与二元酸之间的二酯和(b)具有 16 个或更多碳原子的光学不活泼的非外消旋醇进行酯化反应。耐热脂肪酶和无溶剂条件下，在温度不低于 81℃，常压或减压条件下，基本上不含水，并从反应混合物中分离出具有富含 R 型和 S 型中任一苯基的光学活性醇的步骤。使用耐热脂肪酶可以使用高熔点材料，而无需使用任何溶剂，并且可以在高温下进行酯化反应，从而在更短的时间内完成反应。此外，使用高熔点和高沸点的起始原料，可以利用物理性质的差异，通过简单的提纯步骤，从反应混合物中分离出高纯度、高收率的光学活性醇。特别是在减压条件下进行酯化反应时，光学活性醇的分离和提纯可与反应过程同时进行。