20,23,28,31-Tetrathia-1,9,17-triazapentacyclo[15.8.8.17,11.03,8.010,15]tetratriaconta-3,5,7,9,11(34),12,14-heptaene | 1013937-57-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 20,23,28,31-Tetrathia-1,9,17-triazapentacyclo[15.8.8.17,11.03,8.010,15]tetratriaconta-3,5,7,9,11(34),12,14-heptaene
• 英文别名: 20,23,28,31-tetrathia-1,9,17-triazapentacyclo[15.8.8.17,11.03,8.010,15]tetratriaconta-3,5,7,9,11(34),12,14-heptaene
• CAS: 1013937-57-9
• 化学式: C₂₇H₃₅N₃S₄
• 分子量: 529.859
• InChiKey: ONNLYIGFBNWVIA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  34
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  121
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  1,4,10,13-四噻-7,16-二氮环十八烷 、 4,5-双(溴甲基)吖啶 在 potassium carbonate 作用下， 以 氯仿 为溶剂， 以70%的产率得到20,23,28,31-Tetrathia-1,9,17-triazapentacyclo[15.8.8.17,11.03,8.010,15]tetratriaconta-3,5,7,9,11(34),12,14-heptaene
  参考文献：
  名称：

  New acridine derivatives bearing immobilized azacrown or azathiacrown ligand as fluorescent chemosensors for Hg2+ and Cd2+

  摘要：

  Two new acridine derivatives bearing azacrown or azathiacrown ligand were synthesized as fluorescent chemosensors for Hg(2+) and Cd(2+) in aqueous solution. Compounds 1 and 2 displayed selective CHEF (chelation enhanced fluorescence) effects with Hg(2+) or Cd(2+) among the metal ions examined. The practical use of these probes was demonstrated by their applications to the detection of Hg(2+) and Cd(2+) ions in mammalian cells. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.11.158

文献信息

• New acridine derivatives bearing immobilized azacrown or azathiacrown ligand as fluorescent chemosensors for Hg2+ and Cd2+
  作者：Han Na Lee、Ha Na Kim、K.M.K. Swamy、Min Sun Park、Jimi Kim、Hyunsook Lee、Keun-Hyeung Lee、Sungsu Park、Juyoung Yoon

  DOI：10.1016/j.tetlet.2007.11.158

  日期：2008.2

  Two new acridine derivatives bearing azacrown or azathiacrown ligand were synthesized as fluorescent chemosensors for Hg(2+) and Cd(2+) in aqueous solution. Compounds 1 and 2 displayed selective CHEF (chelation enhanced fluorescence) effects with Hg(2+) or Cd(2+) among the metal ions examined. The practical use of these probes was demonstrated by their applications to the detection of Hg(2+) and Cd(2+) ions in mammalian cells. (c) 2007 Elsevier Ltd. All rights reserved.