ethylsuccinic acid ethyl ester | 76904-20-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethylsuccinic acid ethyl ester
• 英文别名: 3-(Ethyl carboxy)pentanoic acid；3-ethoxycarbonylpentanoic acid
• CAS: 76904-20-6
• 化学式: C₈H₁₄O₄
• 分子量: 174.197
• InChiKey: AUNJHYODGFRHBI-UHFFFAOYSA-N

物化性质

• 沸点：
  80-85 °C(Press: 0.75 Torr)
• 密度：
  1.095±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  ethylsuccinic acid ethyl ester 生成 乙基丁二酸
  参考文献：
  名称：

  PETRAGNANI N.; YONASHIRO MASSAMI, SYNTHESIS, 1980, NO 9, 710-713

  摘要：

  DOI：
• 作为产物：
  描述：

  溴乙酸 、 丁酸乙酯 在 六甲基磷酰三胺 、 lithium hydride 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 以54%的产率得到ethylsuccinic acid ethyl ester
  参考文献：
  名称：

  The Reaction of Lithium α-Lithiocarboxylates (Dianions of Carboxylic Acids) or α-Lithiocarboxylic Esters (Ester Enolates) with α-Halocarboxylic Esters or Lithium α-Halocarboxylates

  摘要：

  DOI：

  10.1055/s-1980-29181

文献信息

• BIOFUELS PRODUCTION FROM BIO-DERIVED CARBOXYLIC-ACID ESTERS
  申请人：Archer Daniels Midland Company

  公开号：US20170044086A1

  公开（公告）日：2017-02-16

  A process for producing biofuels compounds directly from carboxylic acid esters recovered from a fermentation system is described. The process involves taking a fermentation broth that has been reduced to a dry powder containing free organic acids; reacting the carboxylic acid in the powder with an alcohol solvent under a CO 2 -containing atmosphere in substantial absence of any other acid catalyst at a reaction temperature and pressure that corresponds to supercritical, critical or near critical conditions for at least one of the alcohol or CO 2 to synthesize an ester, then subjecting the ester to either hydrogenolysis or hydrogenation to form a biofuel.

  描述了一种直接从从发酵系统中回收的羧酸酯生产生物燃料化合物的过程。该过程涉及采取已经被还原为含有自由有机酸的干粉的发酵液；在含有CO2的气氛下，在几乎没有任何其他酸催化剂的条件下，以相应于至少一种醇或CO2的超临界、临界或接近临界条件的反应温度和压力中，将粉末中的羧酸与醇溶剂反应以合成酯，然后将酯经过氢解或加氢处理以形成生物燃料。
• Process for the preparation of white graft polymer dispersions and flame-retardant polyurethane foams
  申请人：BASF Corporation

  公开号：EP0091036A2

  公开（公告）日：1983-10-12

  White graft polymer dispersions in polyoxyalkylene polyether polyols are employed together with flame retardant compounds to prepare flame retardant polyurethane foams. The polymer dispersions employ less than 0.1 mole of induced unsaturation per mole of polyol mixture. improved processes for the preparation of these polymer dispersions employ either maleate or fumarate derived polyetherester polyols or polyetherester polyols prepared by reacting a polyoxyalkylene polyether polyol with a compound selected from the group consisting of maleic acid, maleic anhydride and fumaric acid and an alkylene oxide in the presence of salts and oxides of divalent metals.

  聚氧亚烷基聚醚多元醇中的白色接枝聚合物分散体与阻燃化合物一起用于制备阻燃聚氨酯泡沫。制备这些聚合物分散体的改进工艺采用马来酸盐或富马酸盐衍生的聚醚酯多元醇或聚醚酯多元醇，聚醚酯多元醇的制备方法是将聚氧亚烷基聚醚多元醇与选自马来酸、马来酸酐、富马酸和氧化亚烷的化合物在二价金属的盐和氧化物存在下进行反应。
• Biofuels production from bio-derived carboxylic-acid esters
  申请人：Archer Daniels Midland Company

  公开号：US10118886B2

  公开（公告）日：2018-11-06

  A process for producing biofuels compounds directly from carboxylic acid esters recovered from a fermentation system is described. The process involves taking a fermentation broth that has been reduced to a dry powder containing free organic acids; reacting the carboxylic acid in the powder with an alcohol solvent under a CO2-containing atmosphere in substantial absence of any other acid catalyst at a reaction temperature and pressure that corresponds to supercritical, critical or near critical conditions for at least one of the alcohol or CO2 to synthesize an ester, then subjecting the ester to either hydrogenolysis or hydrogenation to form a biofuel.

  本文介绍了一种直接利用从发酵系统中回收的羧酸酯生产生物燃料化合物的工艺。该工艺包括：将发酵液还原成含有游离有机酸的干粉；在基本上没有任何其他酸催化剂的情况下，在含二氧化碳的气氛中，使粉末中的羧酸与醇溶剂在反应温度和压力相当于醇或二氧化碳中至少一种物质的超临界、临界或接近临界条件下反应，合成酯，然后将酯进行氢解或氢化，形成生物燃料。
• Microtextured films with improved tactile impression and/or reduced noise perception
  申请人：The Procter & Gamble Company

  公开号：US10975230B2

  公开（公告）日：2021-04-13

  A film layer having a micro-textured surface is provided. The film layer has a continuous phase with one or more thermoplastic polymers, wherein at least one of the thermoplastic polymers is a low-modulus polymer having a 2% secant modulus of less than or equal to 140 MPa, and the film has from 10 wt % to 100 wt % of the low modulus thermoplastic polymer. The film layer also has a discrete phase with from 5 wt % to 45 wt % of a thermoplastic starch.

  提供一种具有微纹理表面的薄膜层。薄膜层的连续相中含有一种或多种热塑性聚合物，其中至少一种热塑性聚合物是低模量聚合物，其 2% 的正割模量小于或等于 140 兆帕，薄膜中的低模量热塑性聚合物含量为 10% 至 100%。薄膜层还有一个离散相，其中热塑性淀粉的含量为 5% 至 45%。
• Treating effects of excessive reactive oxygen species
  申请人：——

  公开号：US20030078241A1

  公开（公告）日：2003-04-24

  A method of treatment is disclosed whereby a nitroxide compound is administered to a patient in a therapeutically effective amount. The nitroxide compound is comprised of a first portion which comprises a nitrogen atom and an oxygen atom bound directly together and an unpaired electron (.NO), and a second portion which provides a negative charge. The first and second portions are connected directly or indirectly by a linking group positioned between and bound to the first portion and the second portion in a manner such that the negative charge of the second portion stabilizes the .NO of the first portion when the nitroxide is present in the patient. By stabilizing the .NO portion of the molecule the nitroxide is allowed to interact with reactive oxygen species in the patient for a longer period of time and modulate adverse effects of those reactive oxygen species.

  本发明公开了一种治疗方法，通过该方法向患者施用治疗有效量的亚硝基化合物。亚硝基化合物由第一部分和第二部分组成，第一部分包括一个直接结合在一起的氮原子和一个氧原子以及一个未配对的电子（.NO），第二部分提供负电荷。第一部分和第二部分通过连接基团直接或间接连接，连接基团位于第一部分和第二部分之间并与第一部分和第二部分结合，当患者体内存在亚硝基化合物时，第二部分的负电荷可稳定第一部分的.NO。通过稳定分子中的.NO部分，亚硝基氧化物可与患者体内的活性氧作用更长时间，并调节这些活性氧的不良影响。