1,5-diacetoxy-nonane | 75178-15-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1,5-diacetoxy-nonane
• 英文别名: 1,5-Diacetoxy-nonan；5-Acetyloxynonyl acetate
• CAS: 75178-15-3
• 化学式: C₁₃H₂₄O₄
• 分子量: 244.331
• InChiKey: BLFXIUWUNSOVCE-UHFFFAOYSA-N

物化性质

• 沸点：
  311.9±25.0 °C(Predicted)
• 密度：
  0.975±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  17
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-丁基四氢吡喃 、 乙酸酐 在 zinc(II) chloride 作用下， 生成 1,5-diacetoxy-nonane
  参考文献：
  名称：

  Paul, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1939, vol. 208, p. 588

  摘要：

  DOI：

文献信息

• Acetylation and formylation of alcohols with triphenylphosphine and carbon tetrabromide in ethyl acetate or ethyl formate
  作者：Hisahiro Hagiwara、Kimie Morohashi、Hitoshi Sakai、Toshio Suzuki、Masayoshi Ando

  DOI：10.1016/s0040-4020(98)00255-5

  日期：1998.5

  Alcohols were acetylated or formylated with triphenylphosphine and carbon tetrabromide in ethyl acetate or ethyl (or methyl) formate at room temperature. THP or TBDMS ether of primary alcohol got converted into formate or acetate under the experimental conditions employed in one pot operation.

  在室温下，在乙酸乙酯或甲酸乙酯（或甲基）中，用三苯膦和四溴化碳将乙醇乙酰化或甲酰化。在一锅操作中使用的实验条件下，伯醇的THP或TBDMS醚转化为甲酸酯或乙酸酯。
• A USEFUL METHOD FOR SELECTIVE ACYLATION OF ALCOHOLS USING 2,2′-BIPYRIDYL-6-YL CARBOXYLATE AND CESIUM FLUORIDE
  作者：Teruaki Mukaiyama、Fong-Chang Pai、Makoto Onaka、Koichi Narasaka

  DOI：10.1246/cl.1980.563

  日期：1980.5.5

  Primary and secondary alcohols are acylated under mild conditions by the use of 2,2′-bipyridyl-6-yl carboxylates and cesium fluoride. Furthermore, the reaction is successfully applied to selective acylation of a primary carbinol group of diols containing primary and secondary carbinol groups or exclusive O-acylation of aromatic amino alcohols.

  伯醇和仲醇在温和条件下通过使用 2,2'-联吡啶-6-基羧酸盐和氟化铯进行酰化。此外，该反应成功地应用于含有伯和仲甲醇基团的二醇的伯醇基团的选择性酰化或芳香氨基醇的排他性O-酰化。
• Solid State Acetylation with Acetylimidazole: Selective Protection of Primary Alcohols and Phenols
  作者：Hisahiro Hagiwara、Kimie Morohashi、Toshio Suzuki、Masayoshi Ando、Isao Yamamoto、Michiharu Kato

  DOI：10.1080/00397919808007174

  日期：1998.6

  Abstract Primary alcohols and phenols have been acetylated with acetylimidazole by the solid state reaction, grinding both substrates with a pestle in a mortar.

  摘要 伯醇和酚通过固态反应与乙酰咪唑乙酰化，在研钵中用研杵研磨两种基材。
• Acetylation of unsymmetrical diols in the presence of Al2O3
  作者：Gary W. Breton、Melissa J. Kurtz、Sharyn L. Kurtz

  DOI：10.1016/s0040-4039(97)00756-9

  日期：1997.6

  The effect of the presence of chromatographic grade Al2O3 on the acetylation of a series of unsymmetrical 1,5-diols was investigated. For diols containing both a primary and a secondary hydroxyl group, it was observed that higher yields of the more hindered secondary acetates were formed in the presence of Al2O3 than the corresponding reactions in solution. (C) 1997 Elsevier Science Ltd.
• MUKAIYAMA TERUAKI; PAI FONG-CHANG; ONAKA MAKOTO; NARASAKA KOICHI, CHEM. LETT., 1980, NO 5, 563-566
  作者：MUKAIYAMA TERUAKI、 PAI FONG-CHANG、 ONAKA MAKOTO、 NARASAKA KOICHI

  DOI：——

  日期：——