ethyl butylthioacetate | 71037-04-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ethyl butylthioacetate
• 英文别名: ethyl 2-(butylthio)acetate；Ethyl 2-butylsulfanylacetate
• CAS: 71037-04-2
• 化学式: C₈H₁₆O₂S
• mdl: MFCD12144346
• 分子量: 176.28
• InChiKey: FYOHYVYTYGUMAZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.875
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  ethyl butylthioacetate 在 双氧水 作用下， 以 乙酸酐 、 溶剂黄146 为溶剂， 生成 ethyl 2-(1-butylsulfonyl)acetate
  参考文献：
  名称：

  van Leusen,A.M.; Strating,J., Recueil des Travaux Chimiques des Pays-Bas, 1965, vol. 84, p. 140 - 150

  摘要：

  DOI：
• 作为产物：
  描述：

  (丁基硫代)乙酸 在 三氯化磷 作用下， 生成 ethyl butylthioacetate
  参考文献：
  名称：

  Is Information Risk a Determinant of Asset Returns?

  摘要：

  ABSTRACTWe investigate the role of information‐based trading in affecting asset returns. We show in a rational expectation example how private information affects equilibrium asset returns. Using a market microstructure model, we derive a measure of the probability of information‐based trading, and we estimate this measure using data for individual NYSE‐listed stocks for 1983 to 1998. We then incorporate our estimates into a Fama and French (1992) asset‐pricing framework. Our main result is that information does affect asset prices. A difference of 10 percentage points in the probability of information‐based trading between two stocks leads to a difference in their expected returns of 2.5 percent per year.

  DOI：

  10.1111/1540-6261.00493

文献信息

• Electrochemical Alkylation of Thiols
  作者：V. A. Petrosyan、M. E. Niyazymbetov、L. D. Konyushkin、V. P. Litvinov

  DOI：10.1055/s-1990-27030

  日期：——

  Synthesis of functionally substituted sulfides by alkylation of electrochemically generated thiolate on platinum or glassy carbon cathodes with organohalides of various structures is reported.

  据报道，通过将电化学生成在铂或玻璃碳阴极上的硫醇盐与各种结构的烷基卤代物进行烷基化反应，合成了功能化的硫化物。
• OXIME ESTER
  申请人：Nishimae Yuichi

  公开号：US20130188270A1

  公开（公告）日：2013-07-25

  Compounds of the formula (I), wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 for example independently of each other are hydro-gen, C 1 -C 20 alkyl, (II), COR 16 or NO 2 , provided that at least one pair of R 1 and R 2 , R 2 and R 3 , R 3 and R 4 , R 5 and R 6 , R 6 and R 7 , or R 7 and R 8 is (III); R 9 , R 10 , R 11 and R 12 for example independently of each other are hydrogen, C 1 -C 20 alkyl which optionally substituted; or R 9 , R 10 , R 11 , and R 12 independently of each other are unsubstituted or substituted phenyl; X is CO or a direct bond; R 13 is for example C 1 -C 20 alkyl which optionally is substituted, C 2 -C 12 alkenyl, C 4 -C 8 cycloalkenyl, C 2 -C 12 alkinyl, C 3 -C 10 -cycloalkyl, phenyl or naphthyl both of which are optionally substituted; R 14 is for example hydrogen, C 3 -C 8 cycloalkyl, C 2 -C 5 alkenyl, C 1 -C 20 alkoxy, C 1 -C 20 alkyl, phenyl or naphthyl; R 15 is for example C 6 -C 20 aryl or C 5 -C 20 heteroaryl; R 16 is for example C 6 -C 20 aryl which is unsubstituted or substituted by one or more C 1 -C 20 alkoxy or C 1 -C 20 alkyl; are in particular suitable as photoinitiators for color filter applications.

  式(I)的化合物，其中R1、R2、R3、R4、R5、R6、R7和R8，例如独立地是氢、C1-C20烷基、(II)、COR16或NO2，条件是至少有一对R1和R2、R2和R3、R3和R4、R5和R6、R6和R7或R7和R8是(III)；R9、R10、R11和R12，例如独立地是氢、C1-C20烷基，可选择地被取代；或者R9、R10、R11和R12独立地是未取代或取代的苯基；X是CO或直接键；R13，例如C1-C20烷基，可选择地被取代，C2-C12烯基，C4-C8环烯基，C2-C12炔基，C3-C10环烷基，苯基或者萘基，两者可选择地被取代；R14，例如氢，C3-C8环烷基，C2-C5烯基，C1-C20烷氧基，C1-C20烷基，苯基或者萘基；R15，例如C6-C20芳基或C5-C20杂芳基；R16，例如C6-C20芳基，未取代或被一个或多个C1-C20烷氧基或C1-C20烷基取代；特别适用于彩色滤光片应用的光引发剂。
• [EN] OXIME ESTER DERIVATIVES OF BENZOCARBAZOLE COMPOUNDS AND THEIR USE AS PHOTOINITIATORS IN PHOTOPOLYMERIZABLE COMPOSITIONS<br/>[FR] DÉRIVÉS ESTER D'OXIME DE BENZOCARBAZOLES ET LEUR UTILISATION COMME PHOTOINITIATEURS DANS DES COMPOSITIONS PHOTOPOLYMÉRISABLES
  申请人：BASF SE

  公开号：WO2012045736A1

  公开（公告）日：2012-04-12

  Compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7 and R8 for example independently of each other are hydro- gen, C1-C20alkyl, (II), COR16 or NO2, provided that at least one pair of R1 and R2, R2 and R3, R3 and R4, R5 and R6, R6 and R7, or R7 and R8 is (III); R9, R10, R11 and R12 for example independently of each other are hydrogen, C1-C20alkyl which optionally substituted; or R9, R10, R11, and R12 independently of each other are unsubstituted or substituted phenyl; X is CO or a direct bond; R13 is for example C1-C20alkyl which optionally is substituted, C2-C12alkenyl, C4- C8cycloalkenyl, C2-C12alkinyl, C3-C10cycloalkyl, phenyl or naphthyl both of which are optionally substituted; R14 is for example hydrogen, C3-C8cycloalkyl, C2-C5alkenyl, C1-C20alkoxy, C1-C20alkyl, phenyl or naphthyl; R15 is for example C6-C20aryl or C5-C20heteroaryl; R16 is for example C6-C20aryl which is unsubstituted or substituted by one or more C1-C20alkoxy or C1-C20alkyl; are in particular suitable as photoinitiators for color filter applications.

  式(I)的化合物，其中R1、R2、R3、R4、R5、R6、R7和R8例如彼此独立地为氢、C1-C20烷基、(II)、COR16或NO2，前提是至少有一对R1和R2、R2和R3、R3和R4、R5和R6、R6和R7或R7和R8为(III)；R9、R10、R11和R12例如彼此独立地为氢、C1-C20烷基，可以选择地取代；或者R9、R10、R11和R12彼此独立地为未取代或取代的苯基；X为CO或直接键；R13例如为C1-C20烷基，可以选择地取代，C2-C12烯基，C4-C8环烯基，C2-C12炔基，C3-C10环烷基，苯基或萘基，两者均可以选择地取代；R14例如为氢、C3-C8环烷基、C2-C5烯基、C1-C20烷氧基、C1-C20烷基、苯基或萘基；R15例如为C6-C20芳基或C5-C20杂芳基；R16例如为未取代或取代的C6-C20芳基，其取代基为一个或多个C1-C20烷氧基或C1-C20烷基；特别适用于彩色滤光片应用的光引发剂。
• S-Substituted derivatives of 8-chloro-6-(2-chlorophenyl)-1-mercaptomethyl-4H-s-triazolo[4,3-a]-1,4-benzodiazepine; Synthesis and pharmacology
  作者：Zdeněk J. Vejdělek、Jan Metyš、Miroslav Protiva

  DOI：10.1135/cccc19830123

  日期：——

  Reactions of 7-chloro-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-thione (XVIII) and its 5-(2-chlorophenyl) analogue XIX with hydrazines of methylthio-, ethylthio-, cyclohexylthio-, phenylthio-, 4-tolylthio-, 4-chlorophenylthio-, benzylthio-, S-(2-dimethylaminoethyl)thio-, 2-furfurylthio- and 3-pyridylmethylthioacetic acid in boiling butanol gave substance VII and the title compounds VIII-XVII. The synthesis of hydrazines XXVIII-XXXII is described. The compounds prepared are very little toxic, have strong discoordinating activity and are very potent as anticonvulsant agents. In this line they are substantially more active than alprazolam (II) and are not far behind triazolam (III).

  7-氯-5-苯基-1,3-二氢-1,4-苯并二氮杂硫杂环己烯-2-硫酮（XVIII）及其5-(2-氯苯基)类似物XIX与甲硫基、乙硫基、环己硫基、苯硫基、对甲苯硫基、对氯苯硫基、苄硫基、S-(2-二甲氨基乙基)硫基、2-呋喃基硫基和3-吡啶甲基硫基乙酸的肼在沸腾的丁醇中反应，得到物质VII和标题化合物VIII-XVII。描述了肼XXVIII-XXXII的合成。制备的化合物毒性很小，具有强烈的去协调活性，并且作为抗惊厥药物非常有效。在这方面，它们比阿普唑仑（II）活性更高，并且与三唑安定（III）相差无几。
• 4-Sulfenyl-2-carbamoyl-4-isoxazolin-3-ones: Biological Isostere to 4-Chloro-2-carbamoyl-4-isoxazolin-3-ones.
  作者：Noriaki KUDO、akamitsu YONEDA、Kazuo SATO、Toyokuni HONMA、Soji SUGAI

  DOI：10.1248/cpb.48.509

  日期：——

  4-Sulfenyl-2-carbamoyl-4-isoxazolin-3-ones (4) were designed on the basis of biological isosterism and prepared in four steps. Some of these compounds showed sufficient pre-emergent herbicidal activities against various kinds of weeds. Among the synthesized compounds, 2-(N-(4-chlorophenyl)-N-isopropylcarbamoyl)-4-ethyl-thio-5-methyl-4-isoxazolin-3-one (4cd) exhibited the most promising activity.

  根据生物异构原理设计了 4-亚磺酰基-2-氨基甲酰基-4-异噁唑啉-3-酮（4），并分四个步骤制备。其中一些化合物对多种杂草具有充分的萌前除草活性。在合成的化合物中，2-(N-(4-氯苯基)-N-异丙基氨基甲酰基)-4-乙硫基-5-甲基-4-异噁唑啉-3-酮（4cd）表现出最有前途的活性。