diethyl 1,2-diallylcyclohex-4-ene-1,2-dicarboxylate | 1262875-50-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: diethyl 1,2-diallylcyclohex-4-ene-1,2-dicarboxylate
• 英文别名: diethyl (1S,2R)-1,2-bis(prop-2-enyl)cyclohex-4-ene-1,2-dicarboxylate
• CAS: 1262875-50-2
• 化学式: C₁₈H₂₆O₄
• 分子量: 306.402
• InChiKey: CTDRZULGFCHBOZ-HDICACEKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  22
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  diethyl 1,2-diallylcyclohex-4-ene-1,2-dicarboxylate 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 二氯甲烷 为溶剂， 反应 6.0h， 以80%的产率得到cis-diethyl 1,4,4a,5,8,8a-hexahydronaphthalene-4a,8a-dicarboxylate
  参考文献：
  名称：

  Synthetic approach to cis and trans-decalins via Diels—Alder reaction and ring-closing metathesis as key steps: further extension to dioxapropellane derivative by ring-closing metathesis

  摘要：

  9,10-Substituted cis and trans-decalins were synthesized by a simple route using the Diels-Alder reaction and ring-closing metathesis (RCM) as key steps. Later, the cis-decalin system has been extended to 3,8-dioxa[8.4.4]propellane derivative by RCM sequence as a key step. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.10.080
• 作为产物：
  描述：

  四氢化邻苯二甲酸酐 在 sodium hexamethyldisilazane 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 正己烷 、 甲苯 为溶剂， 反应 10.5h， 生成 diethyl 1,2-diallylcyclohex-4-ene-1,2-dicarboxylate
  参考文献：
  名称：

  Synthetic approach to cis and trans-decalins via Diels—Alder reaction and ring-closing metathesis as key steps: further extension to dioxapropellane derivative by ring-closing metathesis

  摘要：

  9,10-Substituted cis and trans-decalins were synthesized by a simple route using the Diels-Alder reaction and ring-closing metathesis (RCM) as key steps. Later, the cis-decalin system has been extended to 3,8-dioxa[8.4.4]propellane derivative by RCM sequence as a key step. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.10.080

文献信息

• Synthetic approach to cis and trans-decalins via Diels—Alder reaction and ring-closing metathesis as key steps: further extension to dioxapropellane derivative by ring-closing metathesis
  作者：Sambasivarao Kotha、Arjun S. Chavan、Mirtunjay Kumar Dipak

  DOI：10.1016/j.tet.2010.10.080

  日期：2011.1

  9,10-Substituted cis and trans-decalins were synthesized by a simple route using the Diels-Alder reaction and ring-closing metathesis (RCM) as key steps. Later, the cis-decalin system has been extended to 3,8-dioxa[8.4.4]propellane derivative by RCM sequence as a key step. (C) 2010 Elsevier Ltd. All rights reserved.