3,5,7,4′-tetrahydroxy-8,3′-dimethoxyflavone-3-O-β-D-glucopyranoside | 38836-51-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3,5,7,4′-tetrahydroxy-8,3′-dimethoxyflavone-3-O-β-D-glucopyranoside
• 英文别名: 3,5,7,4'-tetrahydroxy-8,3'-dimethoxyflavone-3-O-β-D-glucopyranoside；4',5,7-trihydroxy-3',8-dimethoxy-3-O-glucosylflavone；gossypetin 8,3'-dimethyl ether 3-glucoside；limocitrin 3-O-β-D-glucopyranoside；limocitrin 3-β-D-glucopyranoside；limocitrin 3-O-β-glucopyranoside；Limocitrin 3-O-beta-D-glucopyranoside；5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-8-methoxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
• CAS: 38836-51-0
• 化学式: C₂₃H₂₄O₁₃
• 分子量: 508.436
• InChiKey: XZGXHUKLGCOGII-FTVHLUNLSA-N

物化性质

• 熔点：
  240-245 °C
• 沸点：
  849.5±65.0 °C(Predicted)
• 密度：
  1.73±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  36
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  205
• 氢给体数：
  7
• 氢受体数：
  13

反应信息

• 作为反应物：
  描述：

  3,5,7,4′-tetrahydroxy-8,3′-dimethoxyflavone-3-O-β-D-glucopyranoside 在 氢氧化钾 作用下， 以 水 为溶剂， 反应 0.33h， 生成 异鼠李素-3-O-葡萄糖苷
  参考文献：
  名称：

  来自景天英亩的黄酮醇苷

  摘要：

  摘要 从景天的地上部分分离到了三种新的黄酮醇苷，即异鼠李素3-(2t´-乙酰)葡萄糖苷、limocitrin 7-glucoside 和limocitrin 3,7-diglucoside。已知化合物槲皮素、异鼠李素及其 3- 和 3,7- 二糖苷、异鼠李素 7-葡萄糖苷和利莫替林及其 3-葡萄糖苷也被鉴定出来。化合物的结构是通过光谱和化学方法确定的。

  DOI：

  10.1016/0031-9422(88)83050-4

文献信息

• Phenolic constituents of the inflorescences of Sorbus torminalis (L.) Crantz
  作者：Monika A. Olszewska、Joanna Marta Roj

  DOI：10.1016/j.phytol.2011.02.005

  日期：2011.6

  Torminaloside, a new acylated flavonol glycoside (3,5,7,4'-tetrahydroxy-3'-methoxyflavone-3-O-[6 ''-O-(3'''-hydroxy-3'''-methylglutaroyl)]-beta-D-galactopyranoside, 6), together with five further methoxylated flavones 1-5, hyperoside (7), isoquercitrin (8), chlorogenic acid (9) and neochlorogenic acid (10), were isolated for the first time from Sorbus torminalis (L.) Crantz. The structures of the isolates were elucidated by extensive spectroscopic studies, including UV, IR, 1D- and 2D-NMR, LSI-MS and HR-LSI-MS experiments. In addition to torminaloside, three further flavonoids: 5,7,4'-trihydroxy-3'-methoxyflavone- 7-O-beta-D-glucopyranoside (1), 3,5,7,4'-tetrahydroxy-8,3'-dimethoxyflavone-3-O-beta-D-glucopyranoside (2), and 3,5,7,4'-tetrahydroxy-3'-methoxyflavone-3-O-beta-D-galactopyranoside (4) were found for the first time in the genus Sorbus. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
• WOLBIS, MARIA, ACTA POL. PHARM., 46,(1989) N-6, C. 500-505
  作者：WOLBIS, MARIA

  DOI：——

  日期：——
• Flavonol glycosides from Sedum acre
  作者：Maria Wolbiś、Maria Królikowska

  DOI：10.1016/0031-9422(88)83050-4

  日期：1988.1

  Abstract Three new flavonol glycosides, isorhamnetin 3-(2t´-acetyl) glucoside, limocitrin 7-glucoside, and limocitrin 3,7-diglucoside, were isolated from the aerial parts of Sedum acre. The known compounds quercetin, isorhamnetin and their 3- and 3,7-di-glucosides, isorhamnetin7-glucoside and limocitrin and its 3-glucoside were also identified. The structure of the compounds was determined by means

  摘要 从景天的地上部分分离到了三种新的黄酮醇苷，即异鼠李素3-(2t´-乙酰)葡萄糖苷、limocitrin 7-glucoside 和limocitrin 3,7-diglucoside。已知化合物槲皮素、异鼠李素及其 3- 和 3,7- 二糖苷、异鼠李素 7-葡萄糖苷和利莫替林及其 3-葡萄糖苷也被鉴定出来。化合物的结构是通过光谱和化学方法确定的。