triallyl acetic acid | 74636-61-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: triallyl acetic acid
• 英文别名: 2,2-Bis(prop-2-enyl)pent-4-enoic acid
• CAS: 74636-61-6
• 化学式: C₁₁H₁₆O₂
• 分子量: 180.247
• InChiKey: PUYNRISIYKUILU-UHFFFAOYSA-N

物化性质

• 沸点：
  288.6±9.0 °C(Predicted)
• 密度：
  0.948±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  triallyl acetic acid 在 氢溴酸 、 三乙胺 作用下， 以 二氯甲烷 、 正戊烷 为溶剂， 反应 3.67h， 生成 3,3-bis(3-bromopropyl)oxan-2-one
  参考文献：
  名称：

  Beaulieu, Normand; Deslongchamps, Pierre, Canadian Journal of Chemistry, 1980, vol. 58, p. 875 - 877

  摘要：

  DOI：
• 作为产物：
  描述：

  二烯丙基丙二酸二乙酯 在 氢氧化钾 、 sodium chloride 、 lithium diisopropyl amide 作用下， 以 乙醇 、 水 、 二甲基亚砜 为溶剂， 反应 462.5h， 生成 triallyl acetic acid
  参考文献：
  名称：

  Beaulieu, Normand; Deslongchamps, Pierre, Canadian Journal of Chemistry, 1980, vol. 58, p. 875 - 877

  摘要：

  DOI：

文献信息

• [EN] 1,2-DIHYDRO-4-HYDROXY-2-OXO-QUINOLINE-3-CARBOXANILIDES AS AHR ACTIVATORS.<br/>[FR] 1,2-DIHYDRO-4-HYDROXY-2-OXO-QUINOLÉINE-3-CARBOXANILIDES EN TANT QU'ACTIVATEURS D'AHR
  申请人：PETTERSSON LARS

  公开号：WO2012050500A1

  公开（公告）日：2012-04-19

  The present invention relates to compounds which are 1, 2-dihydro-4- hydroxy-2-oxo-quinoline-3-carboxanilides, their thieno-pyridone analogs, and prodrugs thereof. This invention specifically relates to such derivatives containing an N-hydrogen in the carboxanilide moiety and which exhibit modulating activity towards the aromatic hydrocarbon receptor (AhR), and, specifically, also to prodrugs thereof. The present invention also relates to use of said compounds as a medicament, and for the treatment of cancer, autoimmune disorders and other disorders with an immunological component, and a pharmaceutical composition comprising one or more of said compounds and a method of treatment.

  本发明涉及化合物，其为1,2-二氢-4-羟基-2-氧基喹啉-3-羧酰苯胺，其噻吩-吡啶酮类似物及其前药。本发明具体涉及含有羧酰苯胺基团中N-氢的衍生物，具有对芳香烃受体（AhR）的调节活性，特别是还涉及其前药。本发明还涉及将所述化合物用作药物，用于治疗癌症、自身免疫性疾病和其他具有免疫成分的疾病，以及包含一种或多种所述化合物的药物组合物和治疗方法。
• 1,2-DIHYDRO-4-HYDROXY-2-OXO-QUINOLINE-3-CARBOXANILIDES AS AHR ACTIVATORS
  申请人：Pettersson Lars

  公开号：US20130203703A1

  公开（公告）日：2013-08-08

  The present invention relates to compounds which are 1,2-dihydro-4-hydroxy-2-oxo-quinoline-3-carboxanilides, their thieno-pyridone analogs, and prodrugs thereof. This invention specifically relates to such derivatives containing an N-hydrogen in the carboxanilide moiety and which exhibit modulating activity towards the aromatic hydrocarbon receptor (AhR), and, specifically, also to prodrugs thereof. The present invention also relates to use of said compounds as a medicament, and for the treatment of cancer, autoimmune disorders and other disorders with an immunological component, and a pharmaceutical composition comprising one or more of said compounds and a method of treatment.

  本发明涉及1,2-二氢-4-羟基-2-氧代-喹啉-3-羧酰苯胺类化合物、其噻吩-吡啶酮类似物以及它们的前药。本发明具体涉及含有羧酰苯胺基团中的N-氢的衍生物，它们表现出对芳香族碳氢受体（AhR）的调节活性，以及它们的前药。本发明还涉及所述化合物作为药物的用途，用于治疗癌症、自身免疫性疾病以及其他具有免疫学成分的疾病，以及一种包含一种或多种所述化合物的药物组合物和一种治疗方法。
• FLUORINE-CONTAINING ETHER COMPOUND, SURFACE TREATMENT AGENT, FLUORINE-CONTAINING ETHER COMPOSITION, COATING LIQUID, ARTICLE, AND PRODUCTION METHOD THEREOF
  申请人：AGC Inc.

  公开号：US20220298180A1

  公开（公告）日：2022-09-22

  Provided are a fluorine-containing ether compound, a fluorine-containing ether composition, and a coating liquid, which can form a surface layer having excellent durability, and an article and production method thereof having a surface layer that has excellent durability and that can maintain water and oil repellency, lubricity, and fingerprint stain removability for a long time. The fluorine-containing ether compound includes a polyfluoropolyether chain, a reactive silyl group, and a linking group that includes a group represented by *—O—C(═O)—**, in which the linking group links the polyfluoropolyether chain arranged on the * side and the reactive silyl group arranged on the ** side.

  提供了一种含氟醚化合物、含氟醚组合物和涂层液，可以形成具有优异耐久性的表面层，并具有具有优异耐久性和能够长时间保持防水、防油、润滑性和指纹污渍去除性的表面层的物品和生产方法。该含氟醚化合物包括聚氟聚醚链、反应性硅基团和包括由*—O—C(═O)—**表示的基团的连接基团，在其中连接基团将排列在*侧的聚氟聚醚链和排列在**侧的反应性硅基团连接起来。
• Metal organic compounds
  申请人：RHONE-POULENC CHEMICALS LIMITED

  公开号：EP0466448A1

  公开（公告）日：1992-01-15

  Metal organic compounds comprising three atoms of cobalt, nickel or bismuth each linked through oxygen atoms to boron or phosphorus and comprising a combination of aliphatic and aromatic carboxylic acid residues are useful as adhesion promoters to promote the adhesion of brass-coated steel to vulcanised rubber.

  金属有机化合物由三个钴、镍或铋原子组成，每个原子通过氧原子与硼或磷相连，并由脂肪族和芳香族羧酸残基组合而成，可用作附着力促进剂，以促进涂有黄铜的钢材与硫化橡胶的附着力。
• Reactive separation process
  申请人：EXXON RESEARCH AND ENGINEERING COMPANY

  公开号：EP0665205A1

  公开（公告）日：1995-08-02

  A method for the reactive separation of a mixture containing C₂ to C₂₆ hydrocarbon(s) and C₂ to C₄₀ oxygenated hydrocarbon(s), comprises heating the mixture in water at temperature and pressure sufficient to cleave the oxygenated hydrocarbons to lower molecular weight products to form an aqueous layer containing water-soluble reaction products and an organic layer primarily containing hydrocarbons.

  一种对含有 C₂ 至 C₂₆ 碳氢化合物和 C₂ 至 C₄₀ 含氧碳氢化合物的混合物进行反应分离的方法，包括在足够的温度和压力下将混合物放入水中加热，使含氧碳氢化合物裂解为分子量较低的产物，形成含有水溶性反应产物的水层和主要含有碳氢化合物的有机层。