2-(3-{1-[3-hydroxypropyl]-3,3-dimethyl-2,3-dihydroindol-2-yliden}-1-propenyl)-3,3-dimethyl-1-[3-hydroxypropyl]-3H-indolium | 400763-55-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2-(3-{1-[3-hydroxypropyl]-3,3-dimethyl-2,3-dihydroindol-2-yliden}-1-propenyl)-3,3-dimethyl-1-[3-hydroxypropyl]-3H-indolium
• 英文别名: Cy3；3-[2-[3-[1-(3-Hydroxypropyl)-3,3-dimethylindol-1-ium-2-yl]prop-2-enylidene]-3,3-dimethylindol-1-yl]propan-1-ol
• CAS: 400763-55-5；446026-77-3
• 化学式: C₂₉H₃₇N₂O₂
• 分子量: 445.625
• InChiKey: RABDLLNSNYDNIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  46.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(3-{1-[3-hydroxypropyl]-3,3-dimethyl-2,3-dihydroindol-2-yliden}-1-propenyl)-3,3-dimethyl-1-[3-hydroxypropyl]-3H-indolium 、 4-甲氧基三苯基氯甲烷 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以29%的产率得到2-(3-{1-[3-(4-methoxyphenyldiphenylmethyloxy)-propyl]-3,3-dimethyl-2,3-dihydroindol-2-yliden}-1-propenyl)-3,3-dimethyl-1-[3-hydroxypropyl]-3H-indolium
  参考文献：
  名称：

  Synthesis of TaqMan probes using bisphosphoramidite of cyanine dye Cy3

  摘要：

  A method of the synthesis of TaqMan probes with the use of bisphosphoramidite of cyanine dye Cy3 was proposed. The synthesis results in two variants of the probes consisting of either one or two oligonucleotide residues (bearing a quencher at the 3' end) attached to the dye, with the first variant being predominant. The RT-PCR probe of the classical structure bearing one oligonucleotide residue was shown to be more efficient as compared to the probe containing two oligonucleotides.

  DOI：

  10.1134/s1068162015050131
• 作为产物：
  描述：

  丁基氨基甲酸酯 在 吡啶 、 乙酸酐 作用下， 反应 16.83h， 生成 2-(3-{1-[3-hydroxypropyl]-3,3-dimethyl-2,3-dihydroindol-2-yliden}-1-propenyl)-3,3-dimethyl-1-[3-hydroxypropyl]-3H-indolium
  参考文献：
  名称：

  Synthesis of TaqMan probes using bisphosphoramidite of cyanine dye Cy3

  摘要：

  A method of the synthesis of TaqMan probes with the use of bisphosphoramidite of cyanine dye Cy3 was proposed. The synthesis results in two variants of the probes consisting of either one or two oligonucleotide residues (bearing a quencher at the 3' end) attached to the dye, with the first variant being predominant. The RT-PCR probe of the classical structure bearing one oligonucleotide residue was shown to be more efficient as compared to the probe containing two oligonucleotides.

  DOI：

  10.1134/s1068162015050131

文献信息

• Method and apparatus for producing a molecular film with an adjusted density
  申请人：Arinaga Kenji

  公开号：US20080003666A1

  公开（公告）日：2008-01-03

  An object of the present invention is to provide a technique that can adjust a molecular density of the film of functional molecules (e.g. DNA molecules), which is utilized for biochips such as DNA chip, to a desired degree efficiently and easily. The method for producing a molecular film with an adjusted density according to the present invention includes forming a molecular film and adjusting a molecular density. In the forming a molecular film, a molecular film composed of molecules is formed on a conductive substrate, wherein the molecule includes a region capable of binding to the conductive substrate at least in a portion thereof. In the density adjusting, a molecular density of the molecular film is adjusted by desorbing a part of the molecules which make up the molecular film from the conductive substrate.
• COLORING COMPOSITION, COLORED CURED FILM, COLOR FILTER, MANUFACTURING METHOD OF THE SAME, AND SOLD STATE IMAGING DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20140151615A1

  公开（公告）日：2014-06-05

  A coloring composition which suppresses color loss of the colored pattern to be formed, and may form a colored pattern which has excellent developability and heat resistance is provided. A colored cured film which suppresses color loss of the colored pattern to be formed, and may form a colored pattern which has excellent developability and heat resistance, a color filter which is provided with the colored pattern, and a manufacturing method thereof are provided. A solid state imaging device which has excellent color loss resistance and heat resistance is provided. A coloring composition of the present invention includes a resin (A) having a dye structure in which a peak area occupied by a component having a molecular weight of 2000 or less is below 10% in respect to a peak area of a total molecular weight distribution of the resin (A) which is measured using gel permeation chromatography.
• COLORING COMPOSITION, COLORED PATTERN, COLOR FILTER AND METHOD OF PRODUCING THE SAME, PATTERN FORMING METHOD, SOLID-STATE IMAGING DEVICE, AND IMAGE DISPLAY DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20140154429A1

  公开（公告）日：2014-06-05

  The objects of the present invention are to provide a coloring composition that is less likely to remain on a pattern of other colors as residues and can inhibit occurrence of coating defects, a colored pattern, a color filter, a method of producing a color filter, a pattern forming method, a solid-state imaging device, and an image display device, each using the same. In order to achieve the above objects, the present invention provides a coloring composition containing a resin (A) having a dye structure, in which in a peak area of the total molecular weight distribution of the resin (A) measured by gel permeation chromatography, a proportion of a peak area of a component having a molecular weight of 20,000 or more is 10% or less.
• US8568966B2
  申请人：——

  公开号：US8568966B2

  公开（公告）日：2013-10-29
• US9470974B2
  申请人：——

  公开号：US9470974B2

  公开（公告）日：2016-10-18