[(2S,3S,4R,5R,6R)-4,5-diacetyloxy-2-methyl-6-[2-[2-[2-[oxido-bis(trimethylsilyloxy)phosphaniumyl]ethoxy]ethoxy]ethoxy]oxan-3-yl] acetate | 1173186-40-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2S,3S,4R,5R,6R)-4,5-diacetyloxy-2-methyl-6-[2-[2-[2-[oxido-bis(trimethylsilyloxy)phosphaniumyl]ethoxy]ethoxy]ethoxy]oxan-3-yl] acetate
• CAS: 1173186-40-7
• 化学式: C₂₄H₄₇O₁₃PSi₂
• 分子量: 630.774
• InChiKey: ZDEVDSVIXFOPCL-QTTGFBFGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  40
• 可旋转键数：
  20
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  157
• 氢给体数：
  0
• 氢受体数：
  13

反应信息

• 作为产物：
  描述：

  (2R,3R,4R,5S,6S)-2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)-6-methyltetrahydro-2H-pyran-3,4,5-triyl triacetate 、 三(三甲代甲硅烷基)亚磷酸盐 反应 5.0h， 以100%的产率得到[(2S,3S,4R,5R,6R)-4,5-diacetyloxy-2-methyl-6-[2-[2-[2-[oxido-bis(trimethylsilyloxy)phosphaniumyl]ethoxy]ethoxy]ethoxy]oxan-3-yl] acetate
  参考文献：
  名称：

  Water-Soluble Rhamnose-Coated Fe₃O₄ Nanoparticles

  摘要：

  Water-soluble biocompatible rhamnose-coated Fe3O4 nanoparticles of 4.0 nm are obtained by covalent anchorage of rhamnose on the nanoparticles surface via a phosphate linker. These nanoparticles present superparamagnetic behavior and nuclear relaxivities in the same order of magnitude as Endorem that make them potential magnetic resonance imaging (MRI) contrast agents of a second generation, where the saccharides represent also specific ligands able to target lectins on skin cells.

  DOI：

  10.1021/ol900949y