1-acetyl-5,5-dimethyl-2-thioxo-imidazolidin-4-one | 38451-03-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-acetyl-5,5-dimethyl-2-thioxo-imidazolidin-4-one
• 英文别名: 1-Acetyl-5,5-dimethyl-2-thioxo-imidazolidin-4-on；1-N-acetyl-5,5-dimethyl-2-thiohydantoin；1-Acetyl-5,5-dimethyl-2-thiohydantoin；1-acetyl-5,5-dimethyl-2-sulfanylideneimidazolidin-4-one
• CAS: 38451-03-5
• 化学式: C₇H₁₀N₂O₂S
• 分子量: 186.235
• InChiKey: NMBVVAVYSDBHMH-UHFFFAOYSA-N

物化性质

• 熔点：
  186-187 °C
• 密度：
  1.32±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  81.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-acetyl-5,5-dimethyl-2-thioxo-imidazolidin-4-one 在 盐酸 作用下， 生成 5,5-二甲基-2-硫代咪唑烷-4-酮
  参考文献：
  名称：

  The Migration of Young Adults from Non‐Metropolitan Counties

  摘要：

  AbstractThis article examines young adult migration from non‐metropolitan counties to either different non‐metropolitan counties or to metropolitan areas. The results show that expected gains in initial earnings provide young entrants to the labor force with a marked incentive to migrate from their non‐metropolitan counties of origin. Initial earnings gains stem, in part, from higher returns to schooling in both metropolitan areas and other non‐metropolitan counties. The propensity to migrate is also sensitive to the costs of migration, which, in turn, are correlated with paternal education and the local presence of extended family.

  DOI：

  10.1111/0002-9092.00159
• 作为产物：
  描述：

  乙酸酐 、 2-甲基丙氨酸 、 硫氰酸铵 生成 1-acetyl-5,5-dimethyl-2-thioxo-imidazolidin-4-one
  参考文献：
  名称：

  The Migration of Young Adults from Non‐Metropolitan Counties

  摘要：

  AbstractThis article examines young adult migration from non‐metropolitan counties to either different non‐metropolitan counties or to metropolitan areas. The results show that expected gains in initial earnings provide young entrants to the labor force with a marked incentive to migrate from their non‐metropolitan counties of origin. Initial earnings gains stem, in part, from higher returns to schooling in both metropolitan areas and other non‐metropolitan counties. The propensity to migrate is also sensitive to the costs of migration, which, in turn, are correlated with paternal education and the local presence of extended family.

  DOI：

  10.1111/0002-9092.00159

文献信息

• Imidazole derivative, pharmaceutically acceptable salt thereof, and
  申请人：Arax Co., Ltd.

  公开号：US05733922A1

  公开（公告）日：1998-03-31

  An imidazole derivative represented by one of formulas (1), wherein R.sub.1, R.sub.2 represents hydrogen atom, lower alkyl, aryl, aralkyl group, or R.sub.1 and R.sub.2 cooperate to represent alkylene, alkylidene, arylalkylidene group, R.sub.3 representing hydrogen atom, lower alkyl or alkanoyl group, or aralkyl or arylcarbonyl group, wherein at least one of A and B represents a group represented by formula (2), wherein m represents an integer 1-4, R.sub.4 representing nitrogen-containing aromatic ring that may be substituted by lower alkyl, alkoxy or alkanoyl group, or phenyl group represented by formula (3), R.sub.5, R.sub.6 representing hydrogen atom, lower alkyl or alkenyl group, or lower alkanoyl or arylcarbonyl group which may be substituted by a halogen atom, R.sub.7 representing hydrogen or halogen atom, hydroxyl or nitro group, or lower alkyl or alkoxy group, wherein the other of A and B represents oxygen or sulfur atom, hydroxyl, mercapto, alkylthio, alkenylthio or aralkylthio group, or group represented by the formula (2), ##STR1##

  一个由以下公式之一表示的咪唑衍生物，其中R.sub.1，R.sub.2代表氢原子，较低的烷基，芳基，芳基烷基，或R.sub.1和R.sub.2合作表示烷基，烷基亚基，芳基烷基亚基，R.sub.3代表氢原子，较低的烷基或烷酰基，或芳基烷基或芳基羰基，其中A和B中的至少一个表示由公式（2）表示的基团，其中m代表整数1-4，R.sub.4代表可能被较低的烷基，烷氧基或烷酰基取代的含氮芳环，或由公式（3）表示的苯基，R.sub.5，R.sub.6代表氢原子，较低的烷基或烯基基团，或可能被卤原子取代的较低的烷酰基或芳基羰基，R.sub.7代表氢或卤原子，羟基或硝基基团，或较低的烷基或烷氧基，其中A和B中的另一个代表氧或硫原子，羟基，巯基，烷硫基，烯基硫基或芳基硫基，或由以下公式表示的基团： ##STR1##
• US5733922A
  申请人：——

  公开号：US5733922A

  公开（公告）日：1998-03-31