diethyl ethylsuccinate | 51251-11-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: diethyl ethylsuccinate
• 英文别名: Diethyl 2-ethylbutanedioate
• CAS: 51251-11-7
• 化学式: C₁₀H₁₈O₄
• 分子量: 202.251
• InChiKey: DEEXZFCTGUGKFF-UHFFFAOYSA-N

物化性质

• 熔点：
  222-225 °C
• 沸点：
  86-87 °C(Press: 0.7 Torr)
• 密度：
  1.006±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  diethyl ethylsuccinate 在 乙醇 、 氢溴酸 、 sodium 、 potassium iodide 、 zinc dibromide 作用下， 生成 3-Ethyl-adipinsaeure
  参考文献：
  名称：

  Keil, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1942, vol. 276, p. 30

  摘要：

  DOI：
• 作为产物：
  描述：

  丁二酸二乙酯 在 lithium diisopropyl amide 作用下， 以 四氢呋喃 为溶剂， 反应 0.25h， 生成 diethyl ethylsuccinate
  参考文献：
  名称：

  Lonq, Nathan R.; Rathke, W., Synthetic Communications, 1981, vol. 11, # 9, p. 687 - 696

  摘要：

  DOI：

文献信息

• Tetramethylammonium phenyltrialkylborates in the photoinduced electron transfer reaction with benzophenone. Generation of alkyl radicals and their addition to activated alkenes
  作者：Alexander Y. Polykarpov、Douglas C. Neckers

  DOI：10.1016/0040-4039(95)01055-m

  日期：1995.7

  Photoinduced one electron oxidation of tetramethylammonium phenyltrialkylborates by the excited state of benzophenone in an acetonitrile/benzene solution containing an excess of activated alkene produces substantially more than one equivalent of the alkyl radicals. The corresponding adducts of alkyl radicals to the alkenes are produced in good yields. No phenyl radical adducts are observed.

  在含有过量活化烯烃的乙腈/苯溶液中，二苯甲酮在二苯甲酮的激发态下，对苯甲基三烷基硼酸四甲铵进行光诱导的一次电子氧化，产生了基本上大于一当量的烷基。烷基自由基与烯烃的相应加合物以良好的产率产生。没有观察到苯基自由基加合物。
• PROCESS FOR DOUBLE CARBONYLATION OF ALLYL ALCOHOLS TO CORRESPONDING DIESTERS
  申请人：EVONIK DEGUSSA GMBH

  公开号：US20170174610A1

  公开（公告）日：2017-06-22

  The invention relates to a process for doubly carbonylating allyl alcohols to the corresponding diesters, wherein a linear or branched allyl alcohol is reacted with a linear or branched alkanol (alcohol) with supply of CO and in the presence of a catalytic system composed of a palladium complex and at least one organic phosphorus ligand and in the presence of a hydrogen halide selected from HCl, HBr and HI.

  该发明涉及一种将烯丙醇双羰基化为相应的二酯的方法，其中线性或支链烯丙醇与线性或支链烷醇（醇）在供应CO的情况下与由钯配合物和至少一种有机磷配体组成的催化系统以及HCl、HBr和HI中选择的氢卤素的存在下反应。
• Die Alkylierung von Formylbernsteinsäureester
  作者：P. H. Payot

  DOI：10.1002/hlca.19590420436

  日期：——

  The preparation of diethyl α-ethoxymethylene-succinate (IIc) from diethyl-α-formyl-succinate (Ia) is described. A study of the C- and O-alkylation of the β-aldehyd-ester Ia is reported.

  描述了由二乙基-α-甲酰基琥珀酸酯（Ia）制备α-乙氧基亚甲基琥珀酸二乙酯（IIc）。报道了对β-醛酯Ia的C-和O-烷基化的研究。
• Metabolites of the anaerobic degradation of diethyl ether by denitrifying betaproteobacterium strain HxN1
  作者：Nico Mitschke、René Jarling、Ralf Rabus、Jens Christoffers、Heinz Wilkes

  DOI：10.1039/d0ob01419b

  日期：——

  Horner–Wadsworth–Emmons reaction to methyl (E)-4-ethoxy-2-pentenoate that was finally hydrogenated to methyl 4-ethoxypentanoate. Methyl (S)-4-ethoxy-3-oxopentanoate was prepared by conversion of (S)-2-ethoxypropanoyl chloride with Meldrum's acid. Reduction of the resulting β-oxoester with NaBH4 or baker's yeast gave both diastereoisomers of methyl 4-ethoxy-3-hydroxypentanoate. The stereocenter at C-3 of the main

  反硝化β-变形杆菌 Aromatoleum sp.在乙醚的共代谢、厌氧降解过程中形成的五种代谢物的组成。通过将质谱和气相色谱数据与合成参考标准的数据进行比较，阐明了菌株 HxN1。此外，建立了代谢物中两个立体中心的绝对构型。基于这些结果，Aromatoleum sp 的二乙醚降解途径。提出了类似于正己烷的 HxN1。( E )-4-乙氧基-2-戊烯酸甲酯的两种对映异构体的合成是通过 ( R )- 或 ( S ) 乙酯的醚化反应完成的)-乳酸，随后酯基水解并还原以提供2-乙氧基-1-丙醇。伯醇通过 Swern 氧化，然后通过 Horner-Wadsworth-Emmons 反应转化为 ( E )-4-乙氧基-2-戊烯酸甲酯，最终氢化成 4-乙氧基戊酸甲酯。( S )-4-乙氧基-3-氧代戊酸甲酯通过 ( S )-2-乙氧基丙酰氯与 Meldrum 酸的转化制备。用NaBH 4或面包酵母还原生
• NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME
  申请人：Abe Koji

  公开号：US20120171581A1

  公开（公告）日：2012-07-05

  Disclosed are a nonaqueous electrolytic solution of an electrolyte dissolved in a nonaqueous solvent, which contains a carboxylate represented by the following general formula (I) in an amount of from 0.01 to 10% by mass of the nonaqueous electrolytic solution; and an electrochemical element using it. (In the formula, R 1 represents an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, or a cyanoalkyl group; R 2 represents a hydrogen atom, an alkoxy group, a formyloxy group, an acyloxy group, an alkoxycarbonyloxy group, an alkanesulfonyloxy group, an arylsulfonyloxy group, an alkylsilyloxy group, a dialkylphosphoryloxy group, an alkoxy(alkyl)phosphoryloxy group, or a dialkoxyphosphoryloxy group; R 3 represents a hydrogen atom, —CH 2 COOR 6 , or an alkyl group; R 4 represents a hydrogen atom or an alkyl group; R 5 has the same meaning as R 2 , or represents a hydrogen atom, an alkyl group, or —CH 2 COOR 7 ; R 6 and R 7 each independently represent an alkyl group, an alkenyl group, an alkynyl group, or a cycloalkyl group; X represents —OR 8 , -A 2 -C≡Y 2 , -A 2 -C(═O)O-A 3 -C≡Y 2 , -A 2 -C(═O)O-A 4 or COOR 1 ; R 5 is the same as R 1 ; A 1 to A 3 each independently represent an alkylene group; A 4 represents an alkyl group; Y 2 represents CH or N; m indicates an integer of from 0 to 4; n indicates 0 or 1.)

  本发明涉及一种非水电解质溶液，其中包含以下述通式（I）表示的羧酸盐，其质量占非水电解质溶液的0.01至10％；以及使用该电解质溶液的电化学元件。（在式中，R1表示烷基、烯基、炔基、环烷基或氰基烷基；R2表示氢原子、烷氧基、甲酰氧基、酰氧基、烷氧羰基氧基、烷基磺酰氧基、芳基磺酰氧基、烷基硅氧基、二烷基磷酰氧基、烷氧（烷基）磷酰氧基或二烷氧基磷酰氧基；R3表示氢原子、-CH2COOR6或烷基；R4表示氢原子或烷基；R5与R2的含义相同，或表示氢原子、烷基或-CH2COOR7；R6和R7各自独立地表示烷基、烯基、炔基或环烷基；X表示-OR8，-A2-C≡Y2，-A2-C（═O）O-A3-C≡Y2，-A2-C（═O）O-A4或COOR1；R5与R1的含义相同；A1至A3各自独立地表示烷基；A4表示烷基；Y2表示CH或N；m表示0至4的整数；n表示0或1。）