racem.-2,3-dichloro-succinic acid | 19922-87-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: racem.-2,3-dichloro-succinic acid
• 英文别名: racem.-2,3-Dichlor-bernsteinsaeure；(R,R)-2,3-Dichlor-bernsteinsaeure；(S,S)-2,3-Dichlor-bernsteinsaeure；(+/-)-2,3-Dichlor-bernsteinsaeure；2,3-Dichlor-bernsteinsaeure；2,3-dichlorosuccinic acid；(R*,S*)-2,3-Dichlorosuccinic acid；2,3-dichlorobutanedioic acid
• CAS: 19922-87-3
• 化学式: C₄H₄Cl₂O₄
• 分子量: 186.979
• InChiKey: XSCRWBSKSVOZOK-UHFFFAOYSA-N

物化性质

• 熔点：
  168°C
• 沸点：
  267.5°C (rough estimate)
• 密度：
  1.6997 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  甲醇 、 racem.-2,3-dichloro-succinic acid 在 硫酸 作用下， 生成 2,3-二氯琥珀酸二甲酯
  参考文献：
  名称：

  Holmberg, Arkiv foer Kemi, vol. 8, # 2, p. 29,34

  摘要：

  DOI：
• 作为产物：
  描述：

  2,3-二氯马来酸 在 铬 作用下， 以 高氯酸 为溶剂， 生成 racem.-2,3-dichloro-succinic acid
  参考文献：
  名称：

  Katakis, Dimitris; Vrachnou-Astra, Ersi; Konstantatos, John, Journal of the Chemical Society, Dalton Transactions, 1986, p. 1491 - 1498

  摘要：

  DOI：

文献信息

• Process for preparing acrylate compound
  申请人：TOSOH CORPORATION

  公开号：US20030139613A1

  公开（公告）日：2003-07-24

  An acrylate compound of formula (4): 1 is produced by allowing an acrylic acid compound of formula (1): 2 to react with an unsaturated compound of formula (2) or (3): 3 In formulae (1) through (4), R 1 and R 2 are H or F, R 3 is H, F, or an alkyl, alkenyl, fluoroalkyl or fluoroalkenyl group, R 4 and R 5 are H, halogen, or an alkyl, alkenyl, halogenated alkyl or halogenated alkenyl group; and X and Y are an unsubstituted or substituted hydrocarbon group, and dashed line - - - - - means that X and Y may be bonded together to form a cyclic structure.

  通过让化学式（1）：2的丙烯酸化合物与化学式（2）或（3）：3的不饱和化合物发生反应，可以制备出化学式（4）：1的丙烯酸酯化合物。在化学式（1）到（4）中，R1和R2为H或F，R3为H、F或烷基、烯基、氟烷基或氟烯基基团，R4和R5为H、卤素或烷基、烯基、卤代烷基或卤代烯基基团；X和Y为未取代或取代的碳氢基团，虚线- - - - - 表示X和Y可以连接在一起形成环状结构。
• Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same
  申请人：Etna-TEC, Ltd.

  公开号：US20180334417A1

  公开（公告）日：2018-11-22

  A method of making a functionalized fluorinated monomer for use in making oligomers and polymers that can be used to improve surface properties of polymer-derived systems, such as coatings. The method of making a functionalized fluorinated monomer includes reacting at least one fluorinated nucleophilic reactant, such as a fluorinated alcohol, with at least one compound containing at least one epoxide group. Other methods include reaction of a fluorinated alcohol with a cyclic carboxylic anhydride. In another embodiment, a method includes reacting a fluorinated mesylate, tosylate or triflate with an amine, alkoxide or phenoxide. In other embodiments, the method includes reacting a fluorinated alcohol with an alkyl halide, or reacting a fluorinated alkyl halide with an amine. The functionalized fluorinated monomers may be used as intermediates and reacted to modify the functional groups thereon. Further, the functionalized fluorinated monomers may be reacted to form polymers or oligomers, or with polymers or oligomers having functional groups to modify the polymer or oligomer through the functional group thereon,

  一种制备用于制备寡聚物和聚合物的官能化氟化单体的方法，可用于改善聚合物衍生系统（如涂层）的表面性能。制备官能化氟化单体的方法包括将至少一种氟化亲核试剂（如氟化醇）与至少一种含有至少一个环氧基团的化合物反应。其他方法包括将氟化醇与环状羧酸酐反应。在另一实施例中，一种方法包括将氟化甲磺酸酯、对甲苯磺酸酯或三氟甲烷磺酸酯与胺、烷氧基或苯氧基反应。在其他实施例中，该方法包括将氟化醇与烷基卤化物反应，或将氟化烷基卤化物与胺反应。这些官能化氟化单体可用作中间体，并可反应以修改其上的官能基团。此外，这些官能化氟化单体可用于与聚合物或寡聚物反应，或与具有官能基团的聚合物或寡聚物反应，通过其上的官能基团修改聚合物或寡聚物。
• Process for producing chromone compound
  申请人：Hibino Hiroaki

  公开号：US20050085664A1

  公开（公告）日：2005-04-21

  A process for producing a dicarboxylic acid compound represented by the formula (4): wherein R 1 and R 2 are the same or different and each represents lower alkyl and the wavy line indicates that this compound is the E- or Z-isomer or a mixture of them, characterized by reacting a compound represented by the formula (2): wherein R 1 , R 2 and the wavy line have the same meanings as the above, and one of X 2 and X 3 represents hydrogen and the other represents halogen, with nitrophenol represented by the formula (3): in the presence of a base; a process for producing a nitrochromone compound represented by the formula (5): wherein R 1 has the same meaning as the above, characterized by reacting the dicarboxylic acid compound or carboxylic acid thereof with an acid; a process for producing an aminochromone compound which comprises reducing the nitrochromone compound; and a process for producing an amidochromone compound which comprises acylating the aminochromone compound are provided.

  提供一种制备式（4）的二羧酸化合物的方法，其中R1和R2相同或不同，每个代表低级烷基，波浪线表示该化合物是E或Z异构体或它们的混合物，其特征在于将式（2）的化合物与硝基酚在碱的存在下反应，式中R1、R2和波浪线的含义与上述相同，X2和X3中的一个代表氢，另一个代表卤素；提供一种制备式（5）的硝基香豆素化合物的方法，其中R1的含义与上述相同，其特征在于将二羧酸化合物或其羧酸与酸反应；提供一种制备氨基香豆素化合物的方法，其包括还原硝基香豆素化合物；以及提供一种制备酰胺香豆素化合物的方法，其包括酰化氨基香豆素化合物。
• EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME
  申请人：HAYASHIBARA CO., LTD.

  公开号：US20150342854A1

  公开（公告）日：2015-12-03

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用皮肤组成物，该组成物可以预防或改善因年龄增长或衰老引起的皮肤问题，如皱纹、细纹、斑点和下垂，并维持或改善皮肤的屏障功能和透明质酸的产生。本发明通过提供一种外用皮肤组成物来实现该目的，该组成物包含水性介质作为基材料，并含有一种或多种从L-抗坏血酸、其衍生物和它们的盐中选择的成分作为有效成分。
• Fire retardant, curable, ethylenically unsaturated compositions and shaped articles prepared from these compositions
  申请人：AKZO N.V.

  公开号：EP0006644A2

  公开（公告）日：1980-01-09

  Curable, ethylenically unsaturated compositions based on an ester groups-containing compound having excellent fire retardant properties as a result of the incorporation therein of a fire retardant amount of N,N'-ethylene bis(sali- cylideneiminato)-Fell and/or the oxidation product derived therefrom. Preferably, use is made of a fitter in an amount of 2 to 60 per cent by weight, calculated on the mixture of filler and components taking part in the curing process in the presence of said iron compound of 0,1 to 5 per cent by weight, calculated on the mixture of fire retardant additive and components taking part in the curing process. An important group of said ethylenically unsaturated compositions are unsaturated polyester resins which are copolymerized with an unsaturated monomer for use in castings, laminated products and other reinforced articles.

  基于含酯基团化合物的可固化乙烯基不饱和组合物，由于加入了一定量的 N,N'-乙烯双(水杨-亚烷基亚氨)-Fell 和/或由其衍生的氧化产物，因此具有优异的阻燃性能。最好使用 2%至 60%（以重量计）的填充剂，以填充剂和参与固化过程的组分的混合物计算，其中存在 0.1%至 5%（以重量计）的铁化合物，以阻燃添加剂和参与固化过程的组分的混合物计算。上述乙烯基不饱和组合物的一个重要类别是不饱和聚酯树脂，它与不饱和单体共聚，用于铸件、层压制品和其他加固制品。