(R)-2-Hydroxy-undecanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (R)-2-Hydroxy-undecanoic acid
• 英文别名: (2R)-2-hydroxyundecanoic acid
• 化学式: C₁₁H₂₂O₃
• 分子量: 202.294
• InChiKey: MNRBGFKCVTVNBA-SNVBAGLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  月桂酸 在 phosphate buffer pH 6.0 、 氧气 、 Triton X-100 作用下， 以 水 为溶剂， 反应 22.0h， 生成 癸醛 、 (R)-2-Hydroxy-undecanoic acid
  参考文献：
  名称：

  Enantioselective α hydroxylation of carboxylic acids with molecular oxygen catalyzed by the α oxidation enzyme system of young pea leaves (Pisum sativum): A substrate selectivity study

  摘要：

  The substrate selectivity of the a oxidation of carboxylic acids I by crude homogenate of young pea leaves was investigated. Saturated fatty acids with 7 to 16 carbon atoms and oleic acid were transformed to the enantiomerically pure (R)-2-hydroxy acids 2 in the presence of molecular oxygen. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0957-4166(96)00283-2

文献信息

• Enantioselective α hydroxylation of carboxylic acids with molecular oxygen catalyzed by the α oxidation enzyme system of young pea leaves (Pisum sativum): A substrate selectivity study
  作者：Waldemar Adam、Michael Lazarus、Chantu R. Saha-Mǒller、Peter Schreier

  DOI：10.1016/0957-4166(96)00283-2

  日期：1996.8

  The substrate selectivity of the a oxidation of carboxylic acids I by crude homogenate of young pea leaves was investigated. Saturated fatty acids with 7 to 16 carbon atoms and oleic acid were transformed to the enantiomerically pure (R)-2-hydroxy acids 2 in the presence of molecular oxygen. Copyright (C) 1996 Elsevier Science Ltd