2-chloroacetyl-4-hydroxyaniline

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-chloroacetyl-4-hydroxyaniline
• 英文别名: 1-(2-Amino-5-hydroxyphenyl)-2-chloroethanone
• 化学式: C₈H₈ClNO₂
• 分子量: 185.61
• InChiKey: DBMWUQCKXUYVKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-羟基苯硫酚 在 氢氧化钾 作用下， 以 甲醇 为溶剂， 生成 2-chloroacetyl-2-hydroxyaniline 、 2-chloroacetyl-4-hydroxyaniline
  参考文献：
  名称：

  COMPOSITION, RECORDING MATERIAL, AND RECORDING SHEET

  摘要：

  公开号：

  EP1375182B1

文献信息

• RECORDING MATERIAL AND RECORDING SHEET
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1375182A1

  公开（公告）日：2004-01-02

  A recording material and a recording sheet free from surface fogging and excellent in dynamic coloring sensitivity, wet heat resistance, heat resistance, light resistance, plasticizer resistance, and water resistance. A recording material comprising a composition containing at least one kind of a compound (1) and at least one kind of a compound (2) and/or at least one kind a compound (3), and a recording sheet having a recording layer formed from the recording material. Compound (1) Compound (2) Compound (3) [in the formulae, R1, R2, R6, R7, R11, R12 indicate hydrogen atom or alkyl radical, a1-a3 integer of 1-6, n1-n3 0, 1 or 2, m1, m4 and m7 0, 1, 2, or 3. R3, R4, R8, R9 R13, R14 indicate alkyl radical or the like, m2, m3, m5, m6, m8 and m9 0, 1 or 2, Y1-Y3 Co or NRCO (R indicates hydrogen atom or the like)]

  一种表面不起雾、动态着色灵敏度、耐湿热性、耐热性、耐光性、耐增塑剂性和耐水性极佳的记录材料和记录薄片。一种记录材料，包括含有至少一种化合物（1）和至少一种化合物（2）和/或至少一种化合物（3）的组合物，以及由记录材料形成记录层的记录薄片。化合物 (1) 化合物 (2) 化合物 (3) [式中，R1、R2、R6、R7、R11、R12 表示氢原子或烷基，a1-a3 为 1-6 的整数，n1-n3 为 0、1 或 2，m1、m4 和 m7 为 0、1、2 或 3。R3、R4、R8、R9、R13、R14 表示烷基或类似物，m2、m3、m5、m6、m8 和 m9 0、1 或 2，Y1-Y3 Co 或 NRCO（R 表示氢原子或类似物）]。
• COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
  申请人：Universität Konstanz

  公开号：EP3833338A1

  公开（公告）日：2021-06-16
• Compounds for Use in the Treatment of Bacterial Infections
  申请人：Universität Konstanz

  公开号：US20210393586A1

  公开（公告）日：2021-12-23

  The present invention relates to a compound which can be used in the treatment of infections with pathogenic bacteria, in particular pathogens mediating pathogenicity by quinolone dependent production of virulence factors, such as e.g. Pseudomonas aeruginosa and species of the genus Burkholderia , and which can be used for treating bacterial or chronic infections or can be used in combination with other anti-bacterial agents, such as antibiotics, to increase sensitivity of the bacteria for treatment of e.g. multiresistant strains in e.g. mammals.
• US7390771B2
  申请人：——

  公开号：US7390771B2

  公开（公告）日：2008-06-24
• [EN] COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS<br/>[FR] COMPOSÉS À UTILISER DANS LE TRAITEMENT D'INFECTIONS BACTÉRIENNES
  申请人：UNIV KONSTANZ

  公开号：WO2020079001A1

  公开（公告）日：2020-04-23

  The present invention relates to a compound which can be used in the treatment of infections with pathogenic bacteria, in particular pathogens mediating pathogenicity by quinolone dependent production of virulence factors, such as e.g. Pseudomonas aeruginosa and species of the genus Burkholderia, and which can be used for treating bacterial or chronic infections or can be used in combination with other anti-bacterial agents, such as antibiotics, to increase sensitivity of the bacteria for treatment of e.g. multiresistant strains in e.g. mammals.