N-[2,6-dimethyl-4-(3,5-dichloro-pyridin-2-yloxy)phenyl]-N'-tert-butylthiourea

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-[2,6-dimethyl-4-(3,5-dichloro-pyridin-2-yloxy)phenyl]-N'-tert-butylthiourea
• 英文别名: N-[2,6-dimethyl-4-(3,5-dichloro-2-pyridyloxy)phenyl]-N'-tert-butylthiourea；1-tert-butyl-3-[4-(3,5-dichloropyridin-2-yl)oxy-2,6-dimethylphenyl]thiourea
• 化学式: C₁₈H₂₁Cl₂N₃OS
• 分子量: 398.356
• InChiKey: FIHVBDSTXNZVAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  78.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-[2,6-dimethyl-4-(3,5-dichloro-pyridin-2-yloxy)phenyl]-N'-tert-butylthiourea 、 2-氯-1-甲基吡啶碘化物 在 三乙胺 作用下， 以 正己烷 、 乙腈 为溶剂， 生成 N-[2,6-dimethyl-4-(3,5-dichloro-pyridin-2-yloxy)phenyl]-N'-tert-butylcarbodiimide
  参考文献：
  名称：

  Pyridyloxy-substituted phenylcarbodiimides as pesticides

  摘要：

  该发明涉及新型取代的氨基甲酸酰胺，其化学式为##STR1##其中R.sub.1是氢、卤素、C.sub.1 -C.sub.10烷基、C.sub.1 -C.sub.5烷氧基、被1至7个卤素原子取代的C.sub.1 -C.sub.5烷氧基，或是C.sub.1 -C.sub.5烷基硫醚；R.sub.2是氢、卤素、C.sub.1 -C.sub.10烷基或C.sub.1 -C.sub.5烷氧基；R.sub.3是氢、C.sub.1 -C.sub.10烷基、卤素、苯氧基、苯硫醚，或是被卤素、甲基、乙基、含有1至7个卤素原子的C.sub.1 -C.sub.3卤代烷基和氰基中的一种取代的苯氧基或苯硫醚，或是吡啶氧基或被卤素和含有1至7个卤素原子的C.sub.1 -C.sub.3卤代烷基中的一种取代的吡啶氧基；R.sub.4是C.sub.1 -C.sub.12烷基、含有总计2至10个碳原子的烷氧基烷基、C.sub.3 -C.sub.10环烷基、C.sub.3 -C.sub.10环烷基甲基、被1至3个C.sub.1 -C.sub.3烷基取代的C.sub.3 -C.sub.10环烷基，或是被1或2个C.sub.3 -C.sub.10环烷基取代的C.sub.1 -C.sub.5烷基，或是含有7至10个碳原子的多环烷基、苯基(C.sub.1 -C.sub.5)烷基或被卤素、三氟甲基、甲氧基或乙氧基取代的苯基(C.sub.1 -C.sub.5)烷基，用于制备这些化合物和含有它们的组合物，用于害虫控制，特别是用于控制攻击植物和动物的昆虫和蜱类，特别是破坏植物的吸食性昆虫。

  公开号：

  US04812466A1

文献信息

• Substituted carbodiimides
  申请人：Ciba-Geigy Corporation

  公开号：US04921876A1

  公开（公告）日：1990-05-01

  The invention relates to novel substituted carbodiimides of the formula ##STR1## wherein R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.5 alkoxy, C.sub.1 -C.sub.5 alkoxy which is substituted by 1 to 7 halogen atoms, or is C.sub.1 -C.sub.5 alkylthio; R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.10 alkyl or C.sub.1 -C.sub.5 alkoxy; R.sub.3 is hydrogen, C.sub.1 -C.sub.10 alkyl, halogen, phenoxy, phenylthio, or is phenoxy or phenylthio, each mono- or disubstituted by a member selected from the group consisting of halogen, methyl, ethyl, C.sub.1 -C.sub.3 haloalkyl containing 1 to 7 halogen atoms and cyano, or is pyridyloxy or pyridyloxy which is mono- or disubstituted by a member selected from the group consisting of halogen and C.sub.1 -C.sub.3 haloalkyl containing 1 to 7 halogen atoms; R.sub.4 is C.sub.1 -C.sub.12 alkyl, alkoxyalkyl containing a total of 2 to 10 carbon atoms, C.sub.3 -C.sub.10 cycloalkyl, C.sub.3 -C.sub.10 cycloalkylmethyl, C.sub.3 -C.sub.10 cycloalkyl which is substituted by 1 to 3 C.sub.1 -C.sub.3 alkyl groups, or is C.sub.1 -C.sub.5 -alkyl which is substituted to 1 to 2 C.sub.3 -C.sub.10 cycloalkyl groups, or is a polycyclic alkyl group containing 7 to 10 carbon atoms, phenyl(C.sub.1 -C.sub.5)alkyl or phenyl(C.sub.1 -C.sub.5)alkyl which is mono- or disubstituted at the phenyl nucleus by halogen, trifluoromethyl, methoxy or ethoxy, to the preparation of these compounds and to compositions containing them for use in pest control, especially for controlling insects and representatives of the order Acarina that attack plants and animals, in particular plant-destructive sucking insects.

  本发明涉及一种新颖的取代的碳二亚胺，其化学式为##STR1##其中，R.sub.1是氢、卤素、C.sub.1-C.sub.10烷基、C.sub.1-C.sub.5烷氧基、1至7个卤素原子取代的C.sub.1-C.sub.5烷氧基，或是C.sub.1-C.sub.5烷基硫醚；R.sub.2是氢、卤素、C.sub.1-C.sub.10烷基或C.sub.1-C.sub.5烷氧基；R.sub.3是氢、C.sub.1-C.sub.10烷基、卤素、苯氧基、苯基硫醚，或是苯氧基或苯基硫醚，每个都是由选自卤素、甲基、乙基、含有1至7个卤素原子的C.sub.1-C.sub.3卤代烷基和氰基的成员单取代或双取代，或是单取代或双取代的吡啶氧基或含有选自卤素和含有1至7个卤素原子的C.sub.1-C.sub.3卤代烷基的吡啶氧基；R.sub.4是C.sub.1-C.sub.12烷基、含有总共2至10个碳原子的烷氧基烷基、C.sub.3-C.sub.10环烷基、C.sub.3-C.sub.10环烷基甲基、取代了1至3个C.sub.1-C.sub.3烷基的C.sub.3-C.sub.10环烷基，或是取代了1至2个C.sub.3-C.sub.10环烷基的C.sub.1-C.sub.5烷基，或是包含7至10个碳原子的多环烷基、苯基(C.sub.1-C.sub.5)烷基或单取代或双取代苯核上取代了卤素、三氟甲基、甲氧基或乙氧基的苯基(C.sub.1-C.sub.5)烷基。本发明还涉及制备这些化合物和含有它们的组合物，用于害虫控制，特别是用于控制攻击植物和动物的昆虫和螨类，特别是破坏植物的吸食昆虫。
• US4812466A
  申请人：——

  公开号：US4812466A

  公开（公告）日：1989-03-14
• US4921876A
  申请人：——

  公开号：US4921876A

  公开（公告）日：1990-05-01
• Pyridyloxy-substituted phenylcarbodiimides as pesticides
  申请人：Ciba-Geigy Corporation

  公开号：US04812466A1

  公开（公告）日：1989-03-14

  The invention relates to novel substituted carbodiimides of the formula ##STR1## wherein R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.5 alkoxy, C.sub.1 -C.sub.5 alkoxy which is substituted by 1 to 7 halogen atoms, or is C.sub.1 -C.sub.5 alkylthio; R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.10 alkyl or C.sub.1 -C.sub.5 alkoxy; R.sub.3 is hydrogen, C.sub.1 -C.sub.10 alkyl, halogen, phenoxy, phenylthio, or is phenoxy or phenylthio, each mono- or disubstituted by a member selected from the group consisting of halogen, methyl, ethyl, C.sub.1 -C.sub.3 haloalkyl containing 1 to 7 halogen atoms and cyano, or is pyridyloxy or pyridyloxy which is mono- or disubstituted by a member selected from the group consisting of halogen and C.sub.1 -C.sub.3 haloalkyl containing 1 to 7 halogen atoms; R.sub.4 is C.sub.1 -C.sub.12 alkyl, alkoxyalkyl containing a total of 2 to 10 carbon atoms, C.sub.3 -C.sub.10 cycloalkyl, C.sub.3 -C.sub.10 cycloalkylmethyl, C.sub.3 -C.sub.10 cycloalkyl which is substituted by 1 to 3 C.sub.1 -C.sub.3 alkyl groups, or is C.sub.1 -C.sub.5 alkyl which is substituted to 1 or 2 C.sub.3 -C.sub.10 cycloalkyl groups, or is a polycyclic alkyl group containing 7 to 10 carbon atoms, phenyl(C.sub.1 -C.sub.5)alkyl or phenyl(C.sub.1 -C.sub.5)alkyl which is mono- or disubstituted at the phenyl nucleus by halogen, trifluoromethyl, methoxy or ethoxy, to the preparation of these compounds and to compositions containing them for use in pest control, especially for controlling insects and representatives of the order Acarina that attack plants and animals, in particular plant-destructive sucking insects.

  该发明涉及新型取代的氨基甲酸酰胺，其化学式为##STR1##其中R.sub.1是氢、卤素、C.sub.1 -C.sub.10烷基、C.sub.1 -C.sub.5烷氧基、被1至7个卤素原子取代的C.sub.1 -C.sub.5烷氧基，或是C.sub.1 -C.sub.5烷基硫醚；R.sub.2是氢、卤素、C.sub.1 -C.sub.10烷基或C.sub.1 -C.sub.5烷氧基；R.sub.3是氢、C.sub.1 -C.sub.10烷基、卤素、苯氧基、苯硫醚，或是被卤素、甲基、乙基、含有1至7个卤素原子的C.sub.1 -C.sub.3卤代烷基和氰基中的一种取代的苯氧基或苯硫醚，或是吡啶氧基或被卤素和含有1至7个卤素原子的C.sub.1 -C.sub.3卤代烷基中的一种取代的吡啶氧基；R.sub.4是C.sub.1 -C.sub.12烷基、含有总计2至10个碳原子的烷氧基烷基、C.sub.3 -C.sub.10环烷基、C.sub.3 -C.sub.10环烷基甲基、被1至3个C.sub.1 -C.sub.3烷基取代的C.sub.3 -C.sub.10环烷基，或是被1或2个C.sub.3 -C.sub.10环烷基取代的C.sub.1 -C.sub.5烷基，或是含有7至10个碳原子的多环烷基、苯基(C.sub.1 -C.sub.5)烷基或被卤素、三氟甲基、甲氧基或乙氧基取代的苯基(C.sub.1 -C.sub.5)烷基，用于制备这些化合物和含有它们的组合物，用于害虫控制，特别是用于控制攻击植物和动物的昆虫和蜱类，特别是破坏植物的吸食性昆虫。