(Z)-1,1,2,2-Tetrafluoro-6,6-dimethyl-5-methylamino-hept-4-en-3-one | 72721-39-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (Z)-1,1,2,2-Tetrafluoro-6,6-dimethyl-5-methylamino-hept-4-en-3-one
• 英文别名: (Z)-1,1,2,2-tetrafluoro-6,6-dimethyl-5-(methylamino)hept-4-en-3-one
• CAS: 72721-39-2
• 化学式: C₁₀H₁₅F₄NO
• 分子量: 241.229
• InChiKey: YCCRAEZRBJAIIP-WAYWQWQTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  methanamine;1,1,2,2-tetrafluoro-6,6-dimethylheptane-3,5-dione 生成 (Z)-1,1,2,2-Tetrafluoro-6,6-dimethyl-5-methylamino-hept-4-en-3-one
  参考文献：
  名称：

  PASHKEVICH, K. I.;FILYAKOVA, V. I., IZV. AN CCCP. CEP. XIM., 1984, N 3, 623-627

  摘要：

  DOI：

文献信息

• Interaction of fluoroalkyl-containing ?-diketones with amines
  作者：V. I. Filyakova、Y. G. Ratner、N. S. Karpenko、K. I. Pashkevich

  DOI：10.1007/bf01430731

  日期：1996.9

  The composition of products of the interaction of asymmetric fluoroalkyl-containing beta-diketones with amines was studied. Mixtures of regioisomeric beta-aminovinylketones and products of cleavage and secondary condensation are formed, depending on the temperature, the solvent, the nature of the fluorinated and nonfluorinated substituents in the beta-diketone, and the basicity of the amine. The major product is a beta-aminovinylketone in which the NH2 group is removed from the fluoroalkyl substituent. No beta-aminovinylimines, products of condensation involving two electrophilic centers, were observed.
• PASHKEVICH K. I.; FILYAKOVA V. I.; SHEJNKER YU. N.; ANISIMOVA O. S.; POST+, IZV. AN CCCP CEP. XIM., 1979, HO 9, 2087-2091
  作者：PASHKEVICH K. I.、 FILYAKOVA V. I.、 SHEJNKER YU. N.、 ANISIMOVA O. S.、 POST+

  DOI：——

  日期：——
• PASHKEVICH, K. I.;FILYAKOVA, V. I., IZV. AN CCCP. CEP. XIM., 1984, N 3, 623-627
  作者：PASHKEVICH, K. I.、FILYAKOVA, V. I.

  DOI：——

  日期：——