(E)-2-ethylhex-2-en-1-ol | 38384-38-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-2-ethylhex-2-en-1-ol
• 英文别名: trans-2-ethyl-2-hexen-1-ol；2-ethyl-hex-2-en-1-ol；2-Ethylhex-2-enol
• CAS: 38384-38-2
• 化学式: C₈H₁₆O
• 分子量: 128.214
• InChiKey: JSRFYJBJQPGAAA-SOFGYWHQSA-N

物化性质

• 沸点：
  195.9±8.0 °C(Predicted)
• 密度：
  0.846±0.06 g/cm3(Predicted)
• 保留指数：
  1051

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-2-ethylhex-2-en-1-ol 在 (π-C5H5)2Zr{OC(CH3)2H}2 、 苯甲醛 作用下， 以 甲苯 为溶剂， 反应 8.0h， 以93%的产率得到(E)-2-ethyl-2-hexenal
  参考文献：
  名称：

  Selective oxidation of alcohol function in allylic alcohols to .alpha.,.beta.-unsaturated carbonyl compounds catalyzed by zirconocene complexes

  摘要：

  DOI：

  10.1021/jo00231a006
• 作为产物：
  描述：

  (E)-2-ethyl-2-hexenal 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 以94%的产率得到(E)-2-ethylhex-2-en-1-ol
  参考文献：
  名称：

  钯催化肟酯与1,1-二取代烯烃的环化反应：α，α-二取代二氢吡咯的合成及对不对称方案的研究。

  摘要：

  我们报告有效的钯催化的肟酯与1,1-二取代的烯烃的Pd催化环化，作为一般进入α，α-二取代的吡咯烷衍生物的基础。我们还证明通过采用合适的手性配体，该化学方法的催化不对称变体是可行的。

  DOI：

  10.1039/c2cc38944d

文献信息

• A Practical and Highly Chemoselective Hydrogenation of Aldehydes with a Copper Catalyst
  作者：Hideo Shimizu、Noboru Sayo、Takao Saito

  DOI：10.1055/s-0028-1216726

  日期：——

  A practical hydrogenation of aldehydes mediated by an inexpensive and easily available base metal, copper, is reported. A copper complex associated with 1,4-bis(diphenylphosphino)butane (DPPB) hydrogenates α,β-unsaturated aldehydes in a highly chemoselective fashion to give allylic alcohols with improved catalytic productivities. The reaction system was also effective for the conversion of simple aldehydes

  报道了一种由廉价且容易获得的贱金属铜介导的醛的实际氢化。与 1,4-双（二苯基膦基）丁烷 (DPPB) 相关的铜络合物以高度化学选择性的方式氢化 α,β-不饱和醛，得到具有更高催化生产率的烯丙醇。该反应体系对于将简单醛转化为相应的醇也很有效。
• Formation of fluorescent products in the reaction of butyraldehyde and methylamine as a model of the reaction of oxidized lipids and proteins.
  作者：Kiyomi KIKUGAWA、Tetsuta KATO、Atsushi IWATA、Akira HAYASAKA

  DOI：10.1248/cpb.37.3061

  日期：——

  Formation of fluorescent compounds in the reaction of butyraldehyde and methylamine at pH 7 and 37°C was investigated as a model of the reaction of xidized lipids and proteins. The reation mixture was treated with borohydride for isolation of the products. Some fluorescent products remained unchanged and the other changed into other fluorescent compounds. One of the fluorescent compounds produced on borohydride treatment was identified as 2, 4-diethyl-2, 5-dihydrofuran, which exhibited fluorescence with an excitation maximum at 345nm and an emission maximum at 406nm. The product may be derived by the condensation of 2 molecules of butyraldehyde in the presence of methylamine. Non-fluorescent products composed of 2 : 1, 3 : 1 and 4 : 1 ratios of butyraldehyde and mehylamine were isolated. The fluorescent products may include self-condensation products of butyraldehyde formed in the presence of methylamine.

  在 pH 7 和 37°C 下，丁醛与甲胺反应生成荧光化合物的形成被研究作为氧化脂质与蛋白质反应的模型。反应混合物经过氢化铵处理以分离产物。一些荧光产物保持不变，而另一些则转变为其他荧光化合物。在氢化铵处理后生成的荧光化合物之一被鉴定为 2, 4-二乙基-2, 5-二氢呋喃，它在 345nm 的激发最大值和 406nm 的发射最大值处表现出荧光。该产物可能是通过在甲胺存在下，两个丁醛分子的缩合反应生成的。分离出的非荧光产物包括 2:1、3:1 和 4:1 比例的丁醛与甲胺的组合。荧光产物可能包括在甲胺存在下形成的丁醛的自缩合产物。
• A convenient approach to (S)-2-ethylhexan-1-ol mediated by baker’s yeast
  作者：Yikang Huang、Fanglin Zhang、Yuefa Gong

  DOI：10.1016/j.tetlet.2005.08.063

  日期：2005.10

  The baker’s yeast (Saccharomyces cerevisiae) mediated asymmetric bioreduction of 2-ethylhex-2-enal (1) went smoothly under a mild condition and afforded a high yield of (S)-2-ethylhexan-1-ol (2a) with excellent enantioselectivity in biphasic system.

  面包酵母（Saccharomyces cerevisiae）介导的2-乙基己-2-烯醛（1）的不对称生物还原反应在温和条件下平稳进行，并提供高产率的（S）-2-乙基己-1-醇（2a），具有出色的对映选择性在双相系统中。
• Synthesis and surfactant properties of symmetric and unsymmetric sulfosuccinic diesters, Aerosol-OT homologues
  作者：Krystyna Baczko、Xavier Chasseray、Chantal Larpent

  DOI：10.1039/b104167n

  日期：2001.11.1

  The synthesis and surfactant behaviour of two series of sulfosuccinic diesters, AOT-related compounds, are described [Aerosol-OT 1: sodium bis(2-ethylhexyl) sulfosuccinate]. The first family contains unsaturated, racemic or enantiopure, 2-ethylhex(en)yl chains with various positions of the double bond. These compounds are readily prepared from the corresponding unsaturated alcohol by the standard two-step procedure; their critical micelle concentrations are higher than those of normal AOT and depend on the position of the double bond. The second series consists of nonsymmetric homologues with two different substituents: various unsymmetrical sulfosuccinic diesters with two enantiopure saturated or unsaturated chains of opposite configuration, or with two different substituents like methyl and 2-ethylhexyl, hydrogenated and deuterated chains as well as saturated and unsaturated chains are described. These unsymmetrical sulfosuccinic diesters are readily obtained in a three-step synthetic procedure involving the regiospecific sulfonation of maleic monoester in aqueous medium. The structure of the sodium 4-alkyl-2-sulfosuccinic acid key intermediate is unambiguously resolved by NMR comparative analysis of the hydrogenated and deuterated derivatives. The surfactant behaviour of some unsymmetrical compounds is studied.

  描述了两类磺基琥珀酸二酯的合成和表面活性剂行为，这些化合物与AOT相关【Aerosol-OT 1：双(2-乙基己基)磺基琥珀酸盐】。第一类包含不饱和的、外消旋或对映纯的2-乙基己(烯)基链，双键的位置各不相同。这些化合物可以通过标准的两步法从相应的不饱和醇中容易地制备而成；它们的临界微胞浓度高于常规AOT，并且取决于双键的位置。第二类由两种不同取代基的非对称同系物组成：描述了带有两条对映纯饱和或不饱和链的各种不对称磺基琥珀酸二酯，具有相反构型，或带有两种不同取代基如甲基和2-乙基己基，氢化和氘化链以及饱和和不饱和链。这些不对称磺基琥珀酸二酯可以通过一种三步合成程序轻松获得，该程序涉及在水相中对马来酸单酯的区域特异性磺化。通过氢化和氘化衍生物的NMR比较分析，明确解析了钠盐4-烷基-2-磺基琥珀酸的关键中间体的结构。对一些不对称化合物的表面活性剂行为进行了研究。
• [EN] USE OF EPOXIDES AS FUNGICIDES<br/>[FR] UTILISATION D'EPOXIDES EN TANT QUE FONGICIDES
  申请人：VALTION TEKNILLINEN

  公开号：WO2005089549A1

  公开（公告）日：2005-09-29

  The present invention relates to the use of one or more epoxides as mould preventive agents, the epoxide being an aliphatic epoxide ester or ether or glycidyl ester or ether, and to a method for preventing mould buildup.

  本发明涉及将一个或多个环氧化合物用作防止霉菌生长的剂，其中环氧化合物为脂肪族环氧酯或醚或环氧乙酸酯或醚，并涉及一种防止霉菌生长的方法。

表征谱图