Aethyl-(β-hydroxy-γ-chlorpropyl)-sulfid | 23451-67-4

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 英文名称: Aethyl-(β-hydroxy-γ-chlorpropyl)-sulfid
• 英文别名: 1-Chloro-3-(ethylsulfanyl)propan-2-ol；1-chloro-3-ethylsulfanylpropan-2-ol
• CAS: 23451-67-4
• 化学式: C₅H₁₁ClOS
• 分子量: 154.661
• InChiKey: IQHIFJVDTZSMEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  45.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Aethyl-(β-hydroxy-γ-chlorpropyl)-sulfid 在 sodium hydroxide 作用下， 以 水 、 苯 为溶剂， 生成 2-piperidinomethoxy-1-(3-methylphenoxy)-3-(ethylsulfanyl)propane
  参考文献：
  名称：

  1-（3-甲基苯氧基）-3-（乙基硫烷基）丙烷的氨基甲氧基衍生物作为润滑油的抗菌添加剂

  摘要：

  在仲胺存在下，基于1-（3-甲基苯氧基）-3-乙基硫丙烷-2-醇和甲醛合成1-（3-甲基苯氧基）-3-（乙基硫烷基）丙烷的新氨基甲氧基衍生物的可行性经过研究。合成的化合物的结构已通过元素分析，IR和1 H NMR光谱以及质谱法证明。已测试了合成的化合物作为抗微生物添加剂的润滑油和抗菌物质，以抗细菌和真菌。已经发现它们有效地抑制了微生物的活性。

  DOI：

  10.1134/s0965544118030131
• 作为产物：
  描述：

  1,3-二氯丙醇 、 乙硫醇钠 在 乙醇 作用下， 生成 Aethyl-(β-hydroxy-γ-chlorpropyl)-sulfid
  参考文献：
  名称：

  65.在简单的三碳体系中，极性和极性连接对互变异构的影响。第五部分：双磺酰基丙烯的质变过程

  摘要：

  DOI：

  10.1039/jr9370000317

文献信息

• METHOD FOR PRODUCING SULFUR-CONTAINING EPOXY COMPOUND
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：US20140371475A1

  公开（公告）日：2014-12-18

  An object of the present invention is to provide a method for producing a sulfur-containing epoxy compound producing no scum-like insoluble matter. According to the present invention, a sulfur-containing halohydrin compound is dripped into and reacted with a mixed solvent containing an organic solvent and a basic compound to provide the method for producing the sulfur-containing epoxy compound. According to aspects of the present invention, the organic solvent is at least one type of compound selected from toluene and benzene, the basic compound is at least one type of compound selected from sodium hydroxide, potassium hydroxide and calcium hydroxide, and the reaction temperature is between −5° C. and 30° C.

  本发明的目的是提供一种生产含硫环氧化合物且不产生类似沉渣般不溶物的方法。根据本发明，将含硫卤代醇化合物滴入并与含有有机溶剂和碱性化合物的混合溶剂反应，以提供生产含硫环氧化合物的方法。根据本发明的方面，有机溶剂至少是从甲苯和苯中选择的一种化合物，碱性化合物至少是从氢氧化钠、氢氧化钾和氢氧化钙中选择的一种化合物，反应温度在-5℃和30℃之间。
• Synthesis and Properties of 1-(Alkylsulfanyl)-3-(morpholin-4-yl)propan-2-yl Arylcarbamates and Arylcarbamothioates
  作者：K. O. K. Iskenderova

  DOI：10.1134/s1070428021120125

  日期：2021.12

  Abstract New arylcarbamates and arylcarbamothioates were synthesized by reactions of 1-(alkylsulfanyl)-3-(morpholin-4-yl)propan-2-ols with aryl isocyanates and aryl isothiocyanates, and their structure was determined by using modern physicochemical analysis methods. The synthesized compounds can be used as anti-corrosion and antimicrobial additives for M-11.

  摘要 1-(烷基硫烷基)-3-(吗啉-4-基)丙-2-醇与异氰酸芳基酯和异硫氰酸芳基酯反应合成了新的芳基氨基甲酸酯和芳基氨基甲硫基酸酯，并采用现代物理化学分析方法确定了它们的结构。合成的化合物可用作M-11的防腐和抗菌添加剂。
• 5-Substituted oxazolidines having herbicide antidote activity, production thereof, herbicidal compositions containing them, use thereof in preventing injury to crops and crop seeds coated therewith
  申请人：STAUFFER CHEMICAL COMPANY

  公开号：EP0021759A1

  公开（公告）日：1981-01-07

  N-haloacyl oxazolidines substituted in the 5-position with oxy or thio containing groups of the formula A-Compounds: wherein XR, is phenoxy, R is selected from the group consisting of haloalkyl, where halo is chloro or bromo, and p-methyl phenylsulfonylamido; and R2 and R3 are independently selected from lower alkyl; B-Compounds: wherein X is selected from the group consisting of oxygen and sulfur; R1 is selected from the group consisting of alkyl and alkenyl; R is selected from the group consisting of haloalkyl, alkylthio and p-tolylsulfonamido; R and R3 are independently selected from the group consisting of hydrogen and lower alkyl, each having 1 to 3 carbon atoms, inclusive; provided that the carbon content of R, + R2 is less than or equal to 6 carbon atoms and further provided that when XR, is alkylthio, then R is other than haloalkyl having 3 to 4 carbon atoms inclusive, and provided that when XR1 is methoxy, R is other than 2,3-dibromopropyl; and in addition a compound selected from the group of compounds consisting of 2,2-dimethyl-3(3-bromopropionyl)5-pentoxymethyl oxazolidine; 2,2-dimethyl-3(5-chlorovaleryl)5-isopropoxymethyl oxazolidine; 2,2-dimethyl-3(5-chlorovaleryl)-5-allyloxymethyl oxazolidine; C-Compounds: wherein X is oxygen or sulfur and R is alkyl; R is selected from the group consisting of haloalkyl, and alkoxy carboalkyl; R2 is selected from the group consisting of phenyl, p-chlorophenyl and p-bromophenyl; and R, is selected from the group consisting of hydrogen and methyl. These new compounds have utility as active herbicidal antidotes to protect against and decrease crop injury when used with thiolcarbamate herbicides, and may be when applied in various ways to achieve this. These ways include soil treatment, seed treatment and in-furrow treatment. Improved herbicidal compositions comprising a first-part of one or more thiolcarbamate herbicides and a second part of an effective antidote compound therefor as defined above are disclosed.

  在 5 位被含氧或硫的基团取代的 N-卤代噁唑烷，其式如下 A-化合物：其中 XR 是苯氧基，R 选自由卤代烷基（其中卤代是氯或溴）和对甲基苯磺酰氨基组成的组；以及 R2 和 R3 独立地选自由低级烷基； B-化合物：其中 X 选自由氧和硫组成的组；R1 选自由烷基（其中卤代是氯或溴）和对甲基苯磺酰氨基组成的组；以及 R2 和 R3 独立地选自由低级烷基：其中 X 选自由氧和硫组成的组；R1 选自由烷基和烯基组成的组；R 选自由卤代烷基、烷硫基和对甲苯磺酰胺组成的组；R 和 R3 独立选自由氢和低级烷基组成的组，每个低级烷基具有 1 至 3 个碳原子（包括 3 个）；条件是 R、+R2 的碳含量小于或等于 6 个碳原子，而且当 XR 为烷硫基时，R 不是具有 3 至 4 个碳原子（包括 3 至 4 个碳原子）的卤代烷基，当 XR1 为甲氧基时，R 不是 2,3-二溴丙基；此外，选自以下化合物组的化合物：2,2-二甲基-3(3-溴丙酰基)-5-戊氧基甲基噁唑烷；2,2-二甲基-3(5-氯戊酰基)-5-异丙氧基甲基噁唑烷；2,2-二甲基-3(5-氯戊酰基)-5-烯丙氧基甲基噁唑烷；C-化合物：其中 X 为氧或硫，R 为烷基； R 选自卤代烷基和烷氧基羧基；R2 选自苯基、对氯苯基和对溴苯基；R 选自氢和甲基。这些新化合物可作为活性除草解毒剂，与硫代氨基甲酸酯类除草剂一起使用时，可防止和减少作物伤害，并可通过各种方法实现这一目的。这些方法包括土壤处理、种子处理和垄内处理。本发明公开了改进的除草组合物，其第一部分包含一种或多种硫代氨基甲酸酯除草剂，第二部分包含上文定义的有效解毒剂化合物。
• Some β-Hydroxypropyl Sulfides and their Derivatives¹
  作者：Thomas K. Todsen、C. B. Pollard、Edward G. Rietz

  DOI：10.1021/ja01165a046

  日期：1950.9
• (Bromodimethyl)sulfonium Bromide–Mediated Thiolysis of Epoxides: An Easy Access to β-Hydroxy Sulfides and Benzoxathiepinones in Solvent-Free Conditions
  作者：M. Shailaja、A. Manjula、B. Vittal Rao

  DOI：10.1080/00397910903458595

  日期：2010.11.16

  A mild, rapid and highly regioselective opening of epoxides by mercaptans to -hydroxy sulfides and benzoxathiepinones has been achieved in excellent yields, using catalytic amount of (bromodimethyl)sulfonium bromide in solvent free reaction conditions.