5-(allyloxy)pentanoic acid | 272116-64-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-(allyloxy)pentanoic acid
• 英文别名: 5-allyloxyvaleric acid；5-Prop-2-enoxypentanoic acid
• CAS: 272116-64-0
• 化学式: C₈H₁₄O₃
• 分子量: 158.197
• InChiKey: DOAFBUUWYAOVAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-(allyloxy)pentanoic acid 在 N-溴代丁二酰亚胺(NBS) 、 (Z)-N-3,5-bis(trifluoromethyl)phenyl-4-(dimethyliminio)pyridine-1(4H)-carbimidothioate 作用下， 以 二氯甲烷 为溶剂， 反应 48.0h， 以45%的产率得到3-(bromomethyl)-1,4-dioxonan-5-one
  参考文献：
  名称：

  Efficient Medium Ring Size Bromolactonization Using a Sulfur-Based Zwitterionic Organocatalyst

  摘要：

  Catalytic bromolactonization of long-chain olefinic acids resulting in the efficient synthesis of medium-sized lactones is reported using a zwitterionic catalyst and stoichiometric N-bromosuccinimide halogen source. The reaction was found to be more efficient at 0 degrees C than at room temperature, which could be attributed to the temperature dependence of the zwitterionic catalyst.

  DOI：

  10.1021/ja307210n
• 作为产物：
  描述：

  1,5-戊二醇 在 Jones reagent 、 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 、 丙酮 、 mineral oil 为溶剂， 生成 5-(allyloxy)pentanoic acid
  参考文献：
  名称：

  Efficient Medium Ring Size Bromolactonization Using a Sulfur-Based Zwitterionic Organocatalyst

  摘要：

  Catalytic bromolactonization of long-chain olefinic acids resulting in the efficient synthesis of medium-sized lactones is reported using a zwitterionic catalyst and stoichiometric N-bromosuccinimide halogen source. The reaction was found to be more efficient at 0 degrees C than at room temperature, which could be attributed to the temperature dependence of the zwitterionic catalyst.

  DOI：

  10.1021/ja307210n

文献信息

• PEPTIDE-PHOSPHOLIPID CONJUGATES
  申请人：Van Nieuwenhze Michael S.

  公开号：US20130345117A1

  公开（公告）日：2013-12-26

  The present invention provides a peptide-phospholipid conjugate of Formula 1: wherein: X is selected from the group consisting of —CR 1 R 2 —, —R 3 —, —O—, —S—, and S + (R 3 )—; Y is selected from the group consisting of a bond, alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, amino, ether, cycloamino, cycloether, aryl heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, to heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl; Z is a peptide comprising 1 to 50 amino acids; R 1 and R 2 each independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, amino, ether, cycloamino, cycloether, aryl, heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl; and R 3 is selected from the group consisting of alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, amino, ether, cycloamino, cycloether, aryl, heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl.

  本发明提供了一种式子为1的肽-磷脂共轭体： 其中：X选自CR1R2，R3，O，S和S+（R3）组成的群；Y选自键，烷基，烯基，炔基，卤代烷基，烷氧基烷基，羟基烷基，氨基，醚，环氨基，环醚，芳基杂芳基，芳基烷基，杂芳基烷基，羟基芳基，芳基醚，环烷基，对杂环烷基，羟基对杂环烷基，卤代对杂环烷基和氨基对杂环烷基；Z是由1到50个氨基酸组成的肽；R1和R2各自独立地选自氢，烷基，烯基，炔基，卤代烷基，烷氧基烷基，羟基烷基，氨基，醚，环氨基，环醚，芳基，杂芳基，芳基烷基，杂芳基烷基，羟基芳基，芳基醚，环烷基，对杂环烷基，羟基对杂环烷基，卤代对杂环烷基和氨基对杂环烷基；R3选自烷基，烯基，炔基，卤代烷基，烷氧基烷基，羟基烷基，氨基烷基，氨基，醚，环氨基，环醚，芳基，杂芳基，芳基烷基，杂芳基烷基，羟基芳基，芳基醚，环烷基，对杂环烷基，羟基对杂环烷基，卤代对杂环烷基和氨基对杂环烷基。
• Fluorine-containing polymer for paints and paint composition containing the polymer
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP0459369A1

  公开（公告）日：1991-12-04

  A fluorine-containing copolymer for paints, having Mn of 5000 to 50000 and Mw/Mn of 2 to 10, which consists essentially of 30 to 70 % by mole of the fluoroolefin unit, 15 to 45 % by mole of the vinyl ether or vinyl ester unit, 1 to 30 % by mole of the hydroxyalkyl vinyl ether unit, and 4 to 30 % by mole of the carboxyl-containing unit wherein the carboxyl group is neutralized in an amount of 30 % or more with ammonia or a tertiary amine. This copolymer can give a good coating film without water spot and dewetting as well as with a good levelling property, while maintaining the excellent properties which a fluorine resin has by nature.

  一种用于涂料的含氟共聚物，其 Mn 为 5000 至 50000，Mw/Mn 为 2 至 10，主要由 30% 至 70% （以摩尔计）的氟烯烃单元、15% 至 45% （以摩尔计）的乙烯基醚或乙烯基酯单元、1% 至 30% （以摩尔计）的羟基烷基乙烯基醚单元和 4% 至 30% （以摩尔计）的含羧基单元组成，其中羧基用氨或叔胺中和的量为 30% 或更多。这种共聚物可以形成良好的涂膜，不会产生水斑和露点，并具有良好的流平性，同时还能保持氟树脂所具有的优良特性。
• AQUEOUS COATING COMPOSITIONS, MANUFACTURING METHOD THEREFOR AND COATING FILM MANUFACTURING METHOD
  申请人：ASAHI GLASS COMPANY, LIMITED

  公开号：EP2336253A1

  公开（公告）日：2011-06-22

  To provide an aqueous coating composition which has a high storage stability and which is capable of forming a coating film excellent in gloss, adhesion and water resistance; a prosses for its production; and a process for forming a coating film by using the aqueous coating composition. An aqueous coating composition comprising a fluoro-olefin copolymer, a pigment, a copolymer (1) (an A-B type block copolymer which is a copolymer having no fluorine atoms or ionic groups and which comprises hydrophilic blocks (A) having repeating units (a) having a polyoxyethylene chain in the side chain, and hydrophobic blocks (B) having repeating units (b) having a hydrocarbon chain in the side chain) and an aqueous medium.

  提供一种贮存稳定性高、能形成光泽度、附着力和耐水性优异的涂膜的水性涂料组合物；其生产方法；以及使用该水性涂料组合物形成涂膜的工艺。 一种水性涂料组合物，包括氟-烯烃共聚物、颜料、共聚物 (1)（A-B 型嵌段共聚物，是一种没有氟原子或离子基团的共聚物，由亲水嵌段 (A) 和疏水嵌段 (B)组成，亲水嵌段 (A) 的重复单元 (a) 的侧链中含有聚氧乙烯链，疏水嵌段 (B) 的重复单元 (b) 的侧链中含有烃链）和水性介质。
• CURABLE RESIN COMPOSITION
  申请人：Asahi Glass Company, Limited

  公开号：EP3239203A1

  公开（公告）日：2017-11-01

  To provide a curable resin composition capable of forming a coating film excellent in the weather resistance and the impact resistance with a high productivity even on a member having a complicated shape for outdoor use. A curable resin composition containing the following fluorinated copolymer (A) and the following compound (B): fluorinated copolymer (A): a fluorinated copolymer having a unit derived from a fluoroolefin, a unit having an ethylenic unsaturated group in its side chain, and a unit having a functional group, wherein the unit having a functional group is at least one member selected from a unit having a hydroxy group, a unit having a carboxy group and a unit having an alkoxysilyl group; compound (B): a compound having an acryloyl group or methacryloyl group and at least two isocyanate groups in one molecule.

  提供一种可固化树脂组合物，即使在室外使用的形状复杂的构件上，也能以较高的生产率形成耐候性和抗冲击性优异的涂膜。 一种可固化树脂组合物，含有以下氟化共聚物（A）和以下化合物（B）： 氟化共聚物 (A)：一种氟化共聚物，其单元来源于氟烯烃，单元侧链中含有乙烯基不饱和基团，单元中含有官能团，其中官能团单元至少选自羟基单元、羧基单元和烷氧基硅基单元中的一个； 化合物 (B)：在一个分子中具有丙烯酰基或甲基丙烯酰基和至少两个异氰酸酯基团的化合物。
• Curable resin composition
  申请人：AGC Inc.

  公开号：US10457815B2

  公开（公告）日：2019-10-29

  Provided is a curable resin composition capable of forming a coating film excellent in the weather resistance and the impact resistance with a high productivity even on a member having a complicated shape for outdoor use. The curable resin composition contains a fluorinated copolymer (A) and a compound (B). The fluorinated copolymer (A) includes a fluorinated copolymer having a unit derived from a fluoroolefin, a unit having an ethylenic unsaturated group in its side chain, and a unit having a functional group, and the unit having a functional group is at least one member selected from a unit having a hydroxy group, a unit having a carboxy group and a unit having an alkoxysilyl group. The compound (B) includes at least one acryloyl group and/or methacryloyl groups and at least two isocyanate groups in one molecule.

  本发明提供了一种可固化树脂组合物，即使在室外使用的形状复杂的构件上也能以较高的生产率形成耐候性和抗冲击性优异的涂膜。这种可固化树脂组合物含有氟化共聚物（A）和化合物（B）。氟化共聚物（A）包括一种氟化共聚物，该共聚物具有由氟烯烃衍生的单元、侧链中具有乙烯不饱和基团的单元和具有官能团的单元，其中具有官能团的单元至少选自具有羟基的单元、具有羧基的单元和具有烷氧基硅基的单元中的一个。化合物（B）在一个分子中至少包括一个丙烯酰基和/或甲基丙烯酰基以及至少两个异氰酸酯基团。