(E)-2-((benzylideneamino)methyl)phenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: (E)-2-((benzylideneamino)methyl)phenol
• 英文别名: anti-N-(o-Hydroxy-benzyl)-N-benzyliden-ammonium-trifluoracetat
• 化学式: C₁₄H₁₃NO
• 分子量: 211.263
• InChiKey: NORFFCXCBWJBPB-XNTDXEJSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.01
• 重原子数：
  16.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  32.59
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  (4S,5S)-2-chloro-3,4-dimethyl-5-phenyl-2-[(E)-3-phenylprop-2-enyl]-1,3,2-oxazasilolidine 、 (E)-2-((benzylideneamino)methyl)phenol 以 二氯甲烷 、 1,2-二氯乙烷 为溶剂， 以91%的产率得到2-(((1S,2R)-1,2-diphenylbut-3enylamino)methyl)phenol
  参考文献：
  名称：

  Highly Enantioselective Imine Cinnamylation with a Remarkable Diastereochemical Switch

  摘要：

  The first general method for the enantioselective cinnamylation of aldimines is reported. The method utilizes a simple chiral cinnamylsilane reagent and is characterized by experimental simplicity and extraordinarily high levels of enantioselectivity. Further, a remarkable and unprecedented diastereochemical reversal has been realized whereby either diastereomer may be accessed from the same trans-cinnamylsilane based upon a subtle change to the imine, thus obviating the usual requirement for both the trans- and cis-cinnamylsilanes.

  DOI：

  10.1021/ja076035h
• 作为产物：
  描述：

  (氨基甲基)-苯酚 、 苯甲醛 以 二氯甲烷 为溶剂， 生成 (E)-2-((benzylideneamino)methyl)phenol
  参考文献：
  名称：

  跨对称动态共价系统：关联的氨基转移和氨基转移反应

  摘要：

  描述了化学转氨反应作为一种新型的动态共价反应的发展。关键的1,3-质子转移在完全催化的控制下进行，可以在胺的存在下与转移进行正交或同时进行，从而快速产生具有高度复杂性的二维动态系统。事实证明，氨基转移-氨基转移系统是完全可逆的，可在几天内保持稳定，可与多种官能团兼容，并且高度可调。动力学研究表明，氨基转移是网络中的限速反应。此外，发现容易获得的奎尼丁是用于亚胺基氨基转移的高度有效的催化剂。

  DOI：

  10.1002/chem.201500520

文献信息

• OLEFIN POLYMERIZATION CATALYSTS, THEIR PRODUCTION AND USE
  申请人：——

  公开号：US20010031843A1

  公开（公告）日：2001-10-18

  This invention relates to a catalyst system comprising an activator and one or more heteroatom substituted phenoxide group 3 to 10 transition metal or lanthanide metal compounds wherein the metal is bound to the oxygen of the phenoxide group and provided that: a) if more than one heteroatom substituted phenoxide is present it is not bridged to the other heteroatom substituted phenoxide, b) if the metal is a group 4 metal then the carbon adjacent to the carbon bound to the oxygen of the phenoxide may not be bound to an aldehyde or an ester, c) the carbon ortho to the carbon bound to the oxygen of the phenoxide may not be bound to the C 1 carbon in a group represented by the formula: 1 wherein R 6 and R 7 are independently hydrogen, halogen, a hydrocarbon group, a heterocyclic compound residue, an oxygen containing group, a nitrogen containing group, a boron containing group, an sulfur containing group, a phosphorus containing group, a silicon containing group, a germanium containing group, or a tin containing group, and R 1 and R 2 may be bonded to each other to form a ring. The activator may be an aluminum alkyl, an alumoxane, a modified alumoxane, a non-coordinating anion, a borane, a borate or a mixture thereof.

  本发明涉及一种催化剂系统，包括一个活化剂和一个或多个杂原子取代的酚氧基3到10族过渡金属或镧系金属化合物，其中金属与酚氧基的氧原子相结合，且满足以下条件： a) 如果存在多个杂原子取代的酚氧基，则它不与其他杂原子取代的酚氧基桥接； b) 如果金属是第4族金属，则与酚氧基氧原子相邻的碳不能与醛或酯结合； c) 与酚氧基氧原子相邻的邻位碳不能与公式1所表示的基团中的C1碳结合，其中R6和R7独立地表示氢、卤素、烃基、杂环化合物残基、含氧基团、含氮基团、含硼基团、含硫基团、含磷基团、含硅基团、含锗基团或含锡基团，R1和R2可以结合形成环。活化剂可以是铝烷基、氧化铝烷、改性氧化铝烷、非配位阴离子、硼烷、硼酸盐或其混合物。
• Olefin polymerization catalysts, their production and use
  申请人：——

  公开号：US20020016254A1

  公开（公告）日：2002-02-07

  This invention relates to a catalyst system comprising an activator and one or more heteroatom substituted phenoxide group 3 to 10 transition metal or lanthanide metal compounds wherein the metal is bound to the oxygen of the phenoxide group and provided that: a) if more than one heteroatom substituted phenoxide is present it is not bridged to the other heteroatom substituted phenoxide, b) if the metal is a group 4 metal then the carbon adjacent to the carbon bound to the oxygen of the phenoxide may not be bound to an aldehyde or an ester, c) the carbon ortho to the carbon bound to the oxygen of the phenoxide may not be bound to the C 1 carbon in a group represented by the formula: 1 wherein R 6 and R 7 are independently hydrogen, halogen, a hydrocarbon group, a heterocyclic compound residue, an oxygen containing group, a nitrogen containing group, a boron containing group, an sulfur containing group, a phosphorus containing group, a silicon containing group, a germanium containing group, or a tin containing group, and R 1 and R 2 may be bonded to each other to form a ring. The activator may be an aluminum alkyl, an alumoxane, a modified alumoxane, a non-coordinating anion, a borane, a borate or a mixture thereof.

  本发明涉及一种催化剂体系，包括一个活化剂和一个或多个杂原子取代的酚氧基3到10族过渡金属或镧系金属化合物，其中金属与酚氧基的氧原子结合，且满足以下条件： a) 如果存在多个杂原子取代的酚氧基，则它们不能桥接到其他杂原子取代的酚氧基； b) 如果金属是4族金属，则相邻碳原子不能与酚氧基的氧原子结合的碳原子结合到醛或酯； c) 相邻于酚氧基的氧原子结合的碳原子的正交碳原子不能与由下式表示的组所代表的C1碳原子结合： 其中R6和R7独立地为氢、卤素、烃基、杂环化合物残基、含氧基团、含氮基团、含硼基团、含硫基团、含磷基团、含硅基团、含锗基团或含锡基团，且R1和R2可以相互连接形成环。活化剂可以是铝烷基、氧化铝烷、改性氧化铝烷、非配位阴离子、硼烷、硼酸盐或其混合物。
• Catalyst system and its use in a polymerization process
  申请人：Gindelberger Edward David

  公开号：US20050043497A1

  公开（公告）日：2005-02-24

  Disclosed is a catalyst system including a phenoxide transition metal catalyst compound and a Lewis acid containing activator, a supported catalyst system thereof, a method of preparing the catalyst system and a process for polymerizing olefin(s) utilizing same.

  本发明公开了一种催化剂体系（包括氧化苯过渡金属催化剂化合物和含路易斯酸的活化剂）、其支撑催化剂体系、制备该催化剂体系的方法以及利用该催化剂体系聚合烯烃的工艺。
• Allylsilane–Vinylarene Cross-Metathesis Enables a Powerful Approach to Enantioselective Imine Allylation
  作者：John D. Huber、Nicholas R. Perl、James L. Leighton

  DOI：10.1002/anie.200705621

  日期：2008.4.7
• A CATALYST SYSTEM AND ITS USE IN A POLYMERIZATION PROCESS
  申请人：Univation Technologies LLC

  公开号：EP1303543A1

  公开（公告）日：2003-04-23