2,4-dioxahexadecane | 34458-41-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,4-dioxahexadecane
• 英文别名: dodecyl methoxymethyl ether；Dodecane, 1-(methoxymethoxy)-；1-(methoxymethoxy)dodecane
• CAS: 34458-41-8
• 化学式: C₁₄H₃₀O₂
• 分子量: 230.391
• InChiKey: BIHXPDSLCWPANX-UHFFFAOYSA-N

物化性质

• 沸点：
  273.4±8.0 °C(Predicted)
• 密度：
  0.845±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  16
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,4-dioxahexadecane 在 low-loading and alkylated polystyrene-supported-SO₃H 作用下， 以 水 为溶剂， 反应 24.0h， 以96%的产率得到十二烷醇
  参考文献：
  名称：

  Catalytic Deprotection of Protected Alcohols in Water Using Low-Loading and Alkylated Polystyrene-Supported Sulfonic Acid

  摘要：

  Catalytic deprotection of various protected alcohols was efficiently conducted using a hydrophobic low-loading and alkylated polystyrene-supported sulfonic acid (LL-ALPS-SO3H) in water as the sole solvent. Transprotection of an alcohol from a silyl ether to the corresponding benzylic ether or ester also proceeded smoothly in water.

  DOI：

  10.1021/jo035178t
• 作为产物：
  描述：

  甲醇 、 2-十二烷氧基乙酸 在 氢氧化钾 作用下， 以66%的产率得到2,4-dioxahexadecane
  参考文献：
  名称：

  Klocke, Elisabeth; Matzeit, Agnes; Gockeln, Marianne, Chemische Berichte, 1993, vol. 126, # 7, p. 1623 - 1630

  摘要：

  DOI：

文献信息

• Organotin-Mediated Preparation of Monothioacetals
  作者：Tsuneo Sato、Takamitsu Kobayashi、Tamehisa Gojo、Enji Yoshida、Junzo Otera、Hitosi Nozaki

  DOI：10.1246/cl.1987.1661

  日期：1987.8.5

  Monothioacetals are obtained by treating the corresponding acetals with organotin thiophenoxides in the presence of BF2·OEt2. The reaction proceeds under mild conditions to provide the desired compounds with high selectivity.

  在 BF2·OEt2 存在下，用有机锡噻吩氧化物处理相应的缩醛得到一硫代缩醛。该反应在温和条件下进行，以高选择性提供所需化合物。
• METHOD FOR PREPARING (E3, Z5) -3,5-ALKADIENYL ACETATE
  申请人：YAMASHITA MIYOSHI

  公开号：US20090143617A1

  公开（公告）日：2009-06-04

  Provided is a method for preparing (E3,Z5)-3,5-alkadienyl acetate and (E3,Z5)-3,5-dodecadienyl acetate which is a sex pheromone of Brazilian apple leafminer. Specifically, provided is a method for preparing (E3,Z5)-3,5-alkadienyl acetate, comprising steps of hydrolyzing 5,5-diethoxy-(Z3)-3-pentenyl methoxymethyl ether in the presence of an acid to obtain 4-formyl-(E3)-butenyl methoxymethyl ether; reacting the 4-formyl-(E3)-butenyl methoxymethyl ether with alkylidene triphenylphosphorane in accordance with the Wittig reaction to obtain (E3,Z5)-3,5-alkadienyl methoxymethyl ether; and obtaining (E3,Z5)-3,5-alkadienyl acetate using the (E3,Z5)-3,5-alkadienyl methoxymethyl ether as a starting substance.

  提供了一种制备巴西苹果叶蛾的性信息素(E3,Z5)-3,5-烯二烯基乙酸酯和(E3,Z5)-3,5-十二烯基乙酸酯的方法。具体来说，提供了一种制备(E3,Z5)-3,5-烯二烯基乙酸酯的方法，包括以下步骤：在酸的存在下水解5,5-二乙氧基-(Z3)-3-戊烯基甲氧甲基醚以获得4-甲醛-(E3)-丁烯基甲氧甲基醚；将4-甲醛-(E3)-丁烯基甲氧甲基醚与烯基三苯基膦照威特希格反应的方法反应以获得(E3,Z5)-3,5-烯二烯基甲氧甲基醚；并且使用(E3,Z5)-3,5-烯二烯基甲氧甲基醚作为起始物质获得(E3,Z5)-3,5-烯二烯基乙酸酯。
• METHOD FOR PRODUCING REDUCED HALIDE COMPOUND HAVING UNDERGONE REDUCTION OF CARBON-CARBON UNSATURATED BOND
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20190322607A1

  公开（公告）日：2019-10-24

  A halide compound having one or more carbon-carbon unsaturated bonds is catalytically reduced with substantially no dehalogenation to produce a reduced halide compound in which at least one of the one or more unsaturated bonds is reduced. Specifically provided is a method for producing a reduced halide compound including steps of: reacting a nickel compound, a zinc compound, and a borohydride compound in a solvent to obtain a reduction catalyst; and subjecting a halide compound having one or more carbon-carbon unsaturated bonds to catalytic reduction in the presence of the reduction catalyst to reduce at least one of the one or more carbon-carbon unsaturated bonds to thereby obtain a reduced halide compound.

  一种卤化物化合物，其具有一个或多个碳-碳不饱和键，经催化还原而几乎不发生去卤反应，以产生一个减少的卤化物化合物，其中至少一个或多个不饱和键被还原。具体提供了一种生产减少的卤化物化合物的方法，包括以下步骤：在溶剂中反应镍化合物、锌化合物和硼氢化物化合物以获得还原催化剂；并在还原催化剂存在的情况下，将具有一个或多个碳-碳不饱和键的卤化物化合物进行催化还原，以减少至少一个或多个碳-碳不饱和键，从而获得减少的卤化物化合物。
• Cleavage of 2-Methoxyethoxymethyl Ethers Catalyzed by Cerium(IV) Ammonium Nitrate (CAN) in Acetic Anhydride
  作者：Kiyoshi Tanemura、Tsuneo Suzuki、Yoko Nishida、Koko Satsumabayashi、Takaaki Horaguchi

  DOI：10.1246/cl.2001.1012

  日期：2001.10

  The reactions of 2-methoxyethoxymethyl (MEM) ethers 1 with a catalytic amount of cerium(IV) ammonium nitrate (CAN) in acetic anhydride gave the corresponding mixed acetal esters 2 and acetates 3.

  2-甲氧基乙氧基甲基 (MEM) 醚 1 与催化量的硝酸铈 (IV) 铵 (CAN) 在乙酸酐中的反应得到相应的混合缩醛酯 2 和乙酸酯 3。
• Novel Silane Compounds and Their Use in Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports
  申请人：Martin Franck

  公开号：US20090005269A1

  公开（公告）日：2009-01-01

  The invention relates to novel silane compounds corresponding to the following formula (I): A-E-X  (I) in which: X represents a silylated group which makes possible the covalent attachment of the silane compound to the hydroxyl or hydride functional groups of a support; E represents an organic spacer group; A represents a group capable of releasing an —OH functional group by acid hydrolysis, the said —OH functional group, after the said hydrolysis, being covalently bonded to E. Use of these silane compounds for functionalizing solid supports and for immobilizing biological molecules on these supports.

  本发明涉及与以下式(I)相对应的新型硅烷化合物： A-E-X  (I) 其中： X代表硅化基团，可以使硅烷化合物共价地附着在支持体的羟基或氢化物官能团上； E代表有机间隔基团； A代表能够通过酸水解释放出—OH官能团的基团，所述—OH官能团在所述水解之后与E共价键合。 使用这些硅烷化合物来功能化固体支持体并将生物分子固定在这些支持体上。