sodium indolinedithiocarbamate | 120981-57-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: sodium indolinedithiocarbamate
• 英文别名: sodium indolyldithiocarbamate；Naindtc；Sodium;2,3-dihydroindole-1-carbodithioate
• CAS: 120981-57-9
• 化学式: C₉H₈NS₂*Na
• 分子量: 217.291
• InChiKey: OQYXUGIPQIDQDP-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.12
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  36.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  sodium indolinedithiocarbamate 生成 2,3-Dihydro-indole-1-carbodithioic acid methyl ester
  参考文献：
  名称：

  FAID-ALLAH, HASSAN M., EGYPT. J. CHEM., 31,(1988) N, C. 295-307

  摘要：

  DOI：
• 作为产物：
  描述：

  二硫化碳 、 吲哚啉 在 sodium hydroxide 作用下， 以 甲醇 为溶剂， 以55%的产率得到sodium indolinedithiocarbamate
  参考文献：
  名称：

  Mononuclear indolyldithiocarbamates of SnCl4 and R2SnCl2: Spectroscopic, thermal characterizations and cytotoxicity assays in vitro

  摘要：

  Several mononuclear Sn compounds ranging from mono to tetrakisindoline dithiocarbamates have been synthesized and characterized. Various spectroscopic techniques in combination with microanalytical data lead to the formation of 1:2 and 1:4 (Sn:Naindtc) type complexes depending on the molar ratio of the sodium salt of indolinedithiocarbamate employed. A symmetrical bidentate coordination of the indolinedithiocarbamate has been observed in all the cases as evident by a single sharp band at 1000 cm(-1) in their IR spectra. The compounds were found to adopt an octahedral arrangement around the Sn atom as evident from their 119 Sn NMR data. The TGA/DSC pro. le of the ligand exhibits a two-stage thermogram while the complexes decompose in three steps leading to the formation of tin-sulfide as the eventual end product. The in vitro cytotoxicity of butyl and phenyl analogues has been studied against the standard human tumor cell lines. The compounds have also been screened for their antifungal and antibacterial activity against E. coli, S. aureus, C. albicans and A. flavus. The results indicated the compounds to be active. (C) 2008 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2007.12.026

文献信息

• Substituent effects of cis-dioxobis(dithiocarbamato) molybdenum(VI) on redox properties: redox potentials for one-electron reduction and second-order rate constants for oxygen atom transfer
  作者：Kei Unoura、Akira Yamazaki、Akira Nagasawa、Yoshikiyo Kato、Hiroki Itoh、Hideaki Kudo、Yutaka Fukuda

  DOI：10.1016/s0020-1693(97)05813-1

  日期：1998.3

  The electrochemical properties of a series of cis-dioxobis(dithiocarbamato)molybdenum(VI) complexes [MoO2(RR′dte)2] (RR′dte = N,N-disubstituted dithiocarbamate) and the oxygen atom transfer reactions between [MoO2(RR′dte)2] and PPh3 in 1,2-C2H4Cl2 at 25°C are systematically investigated. A good correlation between logarithmic values of second-order rate constants k1 of the oxygen atom transfer reactions

  一系列顺式-二氧杂双（二硫代氨基甲酸酯）钼（VI）的电化学性质[MoO 2（RR'dte）2 ]（RR'dte = N，N-二取代的二硫代氨基甲酸酯）和[MoO 2之间的氧原子转移反应对25℃下1,2-C 2 H 4 Cl 2中的（RR'dte）2 ]和PPh 3进行了系统研究。氧原子转移反应的二阶速率常数k 1的对数值与[MoO 2 OP 2 RR'dte）2 ] 0的氧化还原电势E °'具有良好的相关性1个耦合观察到在大范围内的ķ 1（0.012至0.61米每秒2）; log k 1的值随着E 0的增加而线性增加。对于[MoO 2（Bz 2 dte）2 / PPh 2 [MoO 2（Ph 2 dte）2 ] / PPh 1和[MoO 2（BzPhdte）2 ] PPh 1系统，可以准确观察到与相关线的偏离。负激活熵（ΔS '= -114 J mol +1 K +1对于[MoO 2（Et
• Mononuclear indolyldithiocarbamates of SnCl4 and R2SnCl2: Spectroscopic, thermal characterizations and cytotoxicity assays in vitro
  作者：Sadaf Khan、Shahab A.A. Nami、K.S. Siddiqi

  DOI：10.1016/j.jorganchem.2007.12.026

  日期：2008.3

  Several mononuclear Sn compounds ranging from mono to tetrakisindoline dithiocarbamates have been synthesized and characterized. Various spectroscopic techniques in combination with microanalytical data lead to the formation of 1:2 and 1:4 (Sn:Naindtc) type complexes depending on the molar ratio of the sodium salt of indolinedithiocarbamate employed. A symmetrical bidentate coordination of the indolinedithiocarbamate has been observed in all the cases as evident by a single sharp band at 1000 cm(-1) in their IR spectra. The compounds were found to adopt an octahedral arrangement around the Sn atom as evident from their 119 Sn NMR data. The TGA/DSC pro. le of the ligand exhibits a two-stage thermogram while the complexes decompose in three steps leading to the formation of tin-sulfide as the eventual end product. The in vitro cytotoxicity of butyl and phenyl analogues has been studied against the standard human tumor cell lines. The compounds have also been screened for their antifungal and antibacterial activity against E. coli, S. aureus, C. albicans and A. flavus. The results indicated the compounds to be active. (C) 2008 Elsevier B.V. All rights reserved.
• FAID-ALLAH, HASSAN M., EGYPT. J. CHEM., 31,(1988) N, C. 295-307
  作者：FAID-ALLAH, HASSAN M.

  DOI：——

  日期：——