2-(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)isoindoline-1,3-dione | 371923-35-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 2-(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)isoindoline-1,3-dione
• 英文别名: 2-[3-(4-Methyl-2-oxo-2H-chromen-7-yloxy)-propyl]-isoindole-1,3-dione；2-[3-(4-methyl-2-oxochromen-7-yl)oxypropyl]isoindole-1,3-dione
• CAS: 371923-35-2
• 化学式: C₂₁H₁₇NO₅
• 分子量: 363.37
• InChiKey: AWEDHFANBZDMSR-UHFFFAOYSA-N

物化性质

• 沸点：
  581.8±50.0 °C(Predicted)
• 密度：
  1.342±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  72.9
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)isoindoline-1,3-dione 在 1-羟基苯并三唑 、 一水合肼 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 49.0h， 生成 methyl 3,5-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propylcarbamoyl)benzoate
  参考文献：
  名称：

  Intimately bound coumarin and bis(alkylaminostyryl)benzene fragments: synthesis and energy transfer

  摘要：

  A novel trichromophoric assembly was synthesized, where two molecules of 7-alkoxy-4-methylcoumarin, acting as energy donors, were linked at a fixed distance and controlled geometry to an energy-acceptor bis(alkylaminostyryl) unit. Resonance energy transfer between the two different species was demonstrated by a careful spectroscopic analysis. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.01.075
• 作为产物：
  描述：

  羟甲香豆素 、 N-(3-溴丙基)苯二胺 在 potassium carbonate 、 sodium iodide 作用下， 以 丙酮 为溶剂， 反应 12.0h， 以81%的产率得到2-(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)isoindoline-1,3-dione
  参考文献：
  名称：

  Intimately bound coumarin and bis(alkylaminostyryl)benzene fragments: synthesis and energy transfer

  摘要：

  A novel trichromophoric assembly was synthesized, where two molecules of 7-alkoxy-4-methylcoumarin, acting as energy donors, were linked at a fixed distance and controlled geometry to an energy-acceptor bis(alkylaminostyryl) unit. Resonance energy transfer between the two different species was demonstrated by a careful spectroscopic analysis. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.01.075