galactosyl-lactose

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: galactosyl-lactose
• 英文别名: Gal(?1-6)Gal(b1-4)a-Glc；(2R,3R,4S,5R)-2-(hydroxymethyl)-6-[[(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol
• 化学式: C₁₈H₃₂O₁₆
• 分子量: 504.442
• InChiKey: OWEGMIWEEQEYGQ-RCMSHJLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.9
• 重原子数：
  34
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  269
• 氢给体数：
  11
• 氢受体数：
  16

反应信息

• 作为产物：
  描述：

  β-乳糖 生成 galactosyl-lactose
  参考文献：
  名称：

  BETA-HEXOSYL-TRANSFERASES AND USES THEREOF

  摘要：

  本发明通常涉及发现新的重组β-己糖基转移酶（BHT）形式及其用于生产低聚半乳糖（GOS）或作为食品添加剂的用途。

  公开号：

  US20150307856A1

文献信息

• Process for producing skim milk powder of high galacto-oligosaccharide content
  申请人：SNOW BRAND MILK PRODUCTS CO., LTD.

  公开号：EP0458358A1

  公开（公告）日：1991-11-27

  A process for producing skim milk powder containing galacto-oligosaccharide, comprising adding β-galactosidase to concentrated milk prepared by concentrating skim milk, to give rise to an enzymatic reaction; heating the reaction mixture to 70-85oC to terminate the enzymatic reaction; and spray-drying the resulting reaction mixture, and skim milk powder containing galacto-oligosaccharide in an amount of 5% by weight or more.

  一种生产含有低聚半乳糖的脱脂奶粉的工艺，包括向通过浓缩脱脂奶制备的浓缩奶中加入β-半乳糖苷酶，以引起酶促反应；将反应混合物加热到70-85oC，以终止酶促反应；以及喷雾干燥所得反应混合物，制得含有低聚半乳糖的脱脂奶粉，其含量为5%（按重量计）或更多。
• Feed for livestock
  申请人：MATSUTANI CHEMICAL INDUSTRIES CO. LTD.

  公开号：EP0549478A1

  公开（公告）日：1993-06-30

  A feed composition comprising galacto-oligosaccharides for alleviating diarrhea and discharge of soft feces. The composition is useful for livestock over the entire raising period.

  一种含有半乳寡糖的饲料组合物，用于缓解腹泻和软粪便的排出。该组合物适用于整个饲养期的家畜。
• Feed for domestic fowls
  申请人：MATSUTANI CHEMICAL INDUSTRIES CO. LTD.

  公开号：EP0616777A2

  公开（公告）日：1994-09-28

  A feed for domestic fowls which comprises a galacto-oligosaccharide composition which is prepared by heat-treating lactose in the presence of a mineral acid; or by adding an inorganic acid to lactose and then heat-treating the resulting mixture using an extruder. The feed serves to inhibit the formation of fatty liver, to improve the meat quality and the rate of egg laying, to improve the eggshell strength and to reduce the cholesterol content in the egg.

  一种家禽饲料，包括一种半乳寡糖组合物，其制备方法是在矿物酸存在下对乳糖进行热处理；或在乳糖中加入一种无机酸，然后使用挤压机对所得混合物进行热处理。该饲料可抑制脂肪肝的形成，改善肉质和产蛋率，提高蛋壳强度，降低鸡蛋中的胆固醇含量。
• LIVER FAT ACCUMULATION INHIBITORY COMPOSITION, FOOD ADDITIVE FOR LIVER FAT ACCUMULATION INHIBITION, AND METHOD OF INHIBITING LIVER FAT ACCUMULATION
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：EP1010424A1

  公开（公告）日：2000-06-21

  A method of inhibiting liver fat accumulation which comprises administering a conjugated linoleic acid homolog to a mammal or making the mammal ingest it; and a liver fat accumulation inhibitory composition characterized by containing an effective amount of a conjugated linoleic acid homolog together with a support for medicinal preparations or foods. The administration or ingestion of CAL inhibits the total lipid content and the triglyceride content in the liver from increasing, and hence can effectively prevent diseases attributable to fatty liver, such as chronic hepatitis and hepatic cirrhosis.

  一种抑制肝脏脂肪积聚的方法，包括给哺乳动物服用或使哺乳动物摄入共轭亚油酸同系物；以及一种抑制肝脏脂肪积聚的组合物，其特征在于含有有效量的共轭亚油酸同系物和支持药物制剂或食品。服用或摄入 CAL 可抑制肝脏中总脂质含量和甘油三酯含量的增加，从而有效预防由脂肪肝引起的疾病，如慢性肝炎和肝硬化。
• Natural feed additive, a method of preparing said feed additive, a feed mixture containing the feed additive as well as a method of breeding farm animals.
  申请人：Nor-Feed ApS

  公开号：EP1129627A1

  公开（公告）日：2001-09-05

  A natural feed additive comprising an oligosaccharide, a first active component containing saponin based on material from the plants Yucca, Quillaja, Azadirachta and/or Trigonellan, as well as a second active component containing an antibacterially active substance based on material from the plants Citrus, hips, grapes, green pepper and plants of the family Lamiaceae. The feed additive turned out to be very efficient as an addition to animal feed in connection breeding of farm animals.

  一种天然饲料添加剂，包括一种低聚糖、一种含有皂甙的第一活性成分（以 Yucca、Quillaja、Azadirachta 和/或 Trigonellan 植物的材料为基础）以及一种含有抗菌活性物质的第二活性成分（以柑橘、臀部、葡萄、青椒和灯心草科植物的材料为基础）。事实证明，这种饲料添加剂作为动物饲料的添加剂，在农场动物的饲养中非常有效。