(2-sulfanylidenepyridin-1-yl) 2-phenoxyacetate | 128756-51-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (2-sulfanylidenepyridin-1-yl) 2-phenoxyacetate
• CAS: 128756-51-4
• 化学式: C₁₃H₁₁NO₃S
• 分子量: 261.301
• InChiKey: HQQHIOPSRGKHAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.25
• 重原子数：
  18.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  40.46
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  苯基乙烯基砜 、 (2-sulfanylidenepyridin-1-yl) 2-phenoxyacetate 以 二氯甲烷 为溶剂， 反应 0.5h， 生成 3-phenoxy-1-phenylsulphonyl-1-(pyridine-2-thiyl)propane
  参考文献：
  名称：

  Decarboxylative radical addition to vinylsulphones and vinylphosphonium bromide: Some further novel transformations of geminal (pyridine-2-thiyl) phenylsulphones.

  摘要：

  Irradiation of O-acyl derivatives 1 of N-hydroxy- 2-thiopyridone with visible light in the presence of phenyl vinyl sulphone or vinyl triphenylphosphonium bromide leads to the corresponding adducts 8 and 9 which can undergo a wide variety of further transformations.

  DOI：

  10.1016/s0040-4020(01)96163-0
• 作为产物：
  描述：

  苯氧乙酸 在 吡啶 、 草酰氯 作用下， 以 N,N-二甲基甲酰胺 、 苯 为溶剂， 反应 18.5h， 生成 (2-sulfanylidenepyridin-1-yl) 2-phenoxyacetate
  参考文献：
  名称：

  Decarboxylative radical addition to vinylsulphones and vinylphosphonium bromide: Some further novel transformations of geminal (pyridine-2-thiyl) phenylsulphones.

  摘要：

  Irradiation of O-acyl derivatives 1 of N-hydroxy- 2-thiopyridone with visible light in the presence of phenyl vinyl sulphone or vinyl triphenylphosphonium bromide leads to the corresponding adducts 8 and 9 which can undergo a wide variety of further transformations.

  DOI：

  10.1016/s0040-4020(01)96163-0

文献信息

• Further studies on carbon-carbon bond formation based on the radical reactions of acyl derivatives of N-hydroxy-2-thiopyridone
  作者：Derek H.R. Barton、Jadab C. Sarma

  DOI：10.1016/s0040-4039(00)88890-5

  日期：1990.1

  By careful exclusion of oxygen, carbon radicals, generated from the W lamp photolysis of O-acyl derivatives of N-hydroxy-2-thiopyridone, can be added efficiently to methylvinyl ketone. Extension to the radical from pent-4-enoic acid provides another synthesis of cyclopentane derivatives. Analogous additions with other electrophilic olefins are also reported.

  通过仔细地排除氧，可以将由N-羟基-2-硫代吡啶酮的O-酰基衍生物的W灯光解所产生的碳自由基有效地添加到甲基乙烯基酮中。由戊-4-烯酸延伸至自由基提供了环戊烷衍生物的另一种合成方法。还报道了与其他亲电子烯烃的类似添加。
• BARTON, DEREK H. R.;SARMA, JADAB C., TETRAHEDRON LETT., 31,(1990) N4, C. 1965-1968
  作者：BARTON, DEREK H. R.、SARMA, JADAB C.

  DOI：——

  日期：——