5-氨基-2-氯-N-(2,2,2-三氟乙基)苯甲酰胺 | 1016840-18-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 5-氨基-2-氯-N-(2,2,2-三氟乙基)苯甲酰胺
• 英文名称: 5-amino-2-chloro-N-(2,2,2-trifluoroethyl)benzamide
• CAS: 1016840-18-8
• 化学式: C₉H₈ClF₃N₂O
• mdl: MFCD09940945
• 分子量: 252.624
• InChiKey: HRYJBJAGSBDDGJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.222
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  5-氨基-2-氯-N-(2,2,2-三氟乙基)苯甲酰胺 、 3-(pentafluoroethyl)-4-(trifluoromethyl)-1H-pyrazole-5-carbonyl chloride 在 氰化银 silica gel 、 二氯甲烷 、 甲醇 、 盐酸 、 氯化钠 、 magnesium sulfate 、 crude product 、 甲基叔丁基醚 、 环己烷 作用下， 以 二氯甲烷 为溶剂， 反应 16.0h， 以In this way, 49 mg of N-{4-chloro-3-[(2,2,2-trifluoroethyl)carbamoyl]phenyl}-3-(pentafluoroethyl)-4-(trifluoromethyl)-1H-pyrazole-5-carboxamide (11%) were obtained as a colourless solid的产率得到N-{4-chloro-3-[(2,2,2-trifluoroethyl)carbamoyl]phenyl}-3-(pentafluoroethyl)-4-(trifluoromethyl)-1H-pyrazole-5-carboxamide
  参考文献：
  名称：

  halogen-substituted compounds

  摘要：

  本发明涉及通式（I）的化合物，其中基团A1、A2、A3、A4、Lm、Q、R1、T和U具有描述中给出的含义，并且涉及使用这些化合物来控制动物害虫。此外，本发明还涉及制备通式（I）化合物的工艺和中间体。

  公开号：

  US20110301181A1

文献信息

• MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO
  申请人：Dow AgroSciences LLC

  公开号：US20180098541A1

  公开（公告）日：2018-04-12

  This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).

  这份披露涉及具有对节肢动物门、软体动物门和线虫门害虫有用的杀虫性的分子领域，用于生产这种分子的过程，用于这种过程的中间体，含有这种分子的杀虫组合物，以及使用这种杀虫组合物对这些害虫进行处理的过程。这些杀虫组合物可以用作螨虫剂、杀虫剂、螨虫剂、软体动物杀虫剂和线虫杀虫剂。本文件披露了具有以下式（“式一”）的分子。
• Halogen-substituted compounds
  申请人：Maue Michael

  公开号：US08946234B2

  公开（公告）日：2015-02-03

  The invention relates to compounds of the general formula (I), in which the radicals A1, A2, A3, A4, Lm, Q, R1, T and U have the meaning given in the description and to the use of the compounds for controlling animal pests. In addition, the invention relates to processes and intermediates for the preparation of the compounds according to formula (I).

  本发明涉及通式（I）的化合物，其中基团A1、A2、A3、A4、Lm、Q、R1、T和U的含义如描述中所给，并且涉及将该化合物用于控制动物害虫。此外，本发明还涉及用于制备通式（I）化合物的过程和中间体。
• Novel halogen-substituted compounds
  申请人：Bayer CropScience AG

  公开号：US20150099766A1

  公开（公告）日：2015-04-09

  The invention relates to compounds of the general formula (I), in which the radicals A 1 , A 2 , A 3 , A 4 , Lm, Q, R 1 , T and U have the meaning given in the description and to the use of the compounds for controlling animal pests. In addition, the invention relates to processes and intermediates for the preparation of the compounds according to formula (I).

  本发明涉及一般式（I）的化合物，其中基团A1，A2，A3，A4，Lm，Q，R1，T和U的含义如说明书中所述，并且涉及使用这些化合物来控制动物害虫。此外，本发明还涉及制备公式（I）化合物的过程和中间体。
• MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO
  申请人：Corteva Agriscience LLC

  公开号：EP3971166A1

  公开（公告）日：2022-03-23

  This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula ("Formula One").

  本公开涉及对节肢动物门、软体动物门和线虫动物门害虫具有杀虫作用的分子、生产此类分子的工艺、用于此类工艺的中间体、含有此类分子的杀虫组合物以及使用此类杀虫组合物对付此类害虫的工艺。这些杀虫组合物可用作杀螨剂、杀虫剂、杀螨剂、杀软体动物剂和杀线虫剂等。本文公开了具有下式（"式一"）的分子。
• Molecules having pesticidal utility and intermediates, compositions and processes related thereto
  申请人：Dow AgroSciences LLC

  公开号：US10258045B2

  公开（公告）日：2019-04-16

  This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).

  本公开涉及对节肢动物门、软体动物门和线虫动物门害虫具有杀虫作用的分子、生产此类分子的工艺、用于此类工艺的中间体、含有此类分子的杀虫组合物以及使用此类杀虫组合物对付此类害虫的工艺。这些杀虫组合物可用作杀螨剂、杀虫剂、杀螨剂、杀软体动物剂和杀线虫剂等。本文公开了具有下式（"式一"）的分子。