2,2-dibromocyclopropane-1-methanol | 22084-99-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2-dibromocyclopropane-1-methanol
• 英文别名: (2,2-dibromocyclopropyl)methanol；2,2-Dibromocyclopropanmethanol；1,1-Dibrom-2-hydroxymethyl-cyclopropan
• CAS: 22084-99-7
• 化学式: C₄H₆Br₂O
• 分子量: 229.899
• InChiKey: WGGWTNZMORMBKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,2-dibromocyclopropane-1-methanol 在 碳酸氢钠 、 2,2,6,6-tetramethyl-4-benzoyloxypiperidine-1-oxide 、 sodium bromide 作用下， 以 二氯甲烷 、 水 为溶剂， 以98%的产率得到2,2-dibromocyclopropanecarbaldehyde
  参考文献：
  名称：

  Electrochemical and chemical oxidation of alcohols in a two-phase system using N-oxopiperidinium salt: Synthesis of 4-chlorobutanal, formylcyclopropanes, andm-phenoxybenzaldehyde

  摘要：

  Oxidation of 4-chlorobutanol-1, cyclopropylcarbinols, and m-phenoxybenzyl alcohol with electrogenerated bromine, molecular bromine, and sodium hypochlorite using N-oxopiperidinium salt in the two-phase system CH2Cl2-water gave the corresponding carbonyl compounds with good yields.

  DOI：

  10.1007/bf01150901
• 作为产物：
  描述：

  1,1-二溴-2-乙烯基环丙烷 生成 2,2-dibromocyclopropane-1-methanol
  参考文献：
  名称：

  Holm,K.H. et al., Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1978, vol. 32, p. 693 - 695

  摘要：

  DOI：

文献信息

• AMIDINE COMPOUND AND USE THEREOF
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20160046564A1

  公开（公告）日：2016-02-18

  An amidine compound represented by formula (1) wherein R 1 , R 2 , R 3 , R 4 and R 5 are the same or different and represent a C1 to C5 alkyl group optionally having one or more halogen atoms or the like; R 6 and R 7 are a hydrogen atom or the like; R 8 and R 9 are the same or different and represent a C1 to C3 alkyl group optionally having one or more halogen atoms or the like; and R 10 and R 11 are the same or different and represent a C1 to C6 alkyl group optionally having one or more halogen atoms or the like, has an excellent control effect on plant diseases.

  化学式（1）所代表的一种胍化合物 其中R1、R2、R3、R4和R5相同或不同，代表一个C1到C5烷基基团，可选地具有一个或多个卤素原子或类似物；R6和R7是氢原子或类似物；R8和R9相同或不同，代表一个C1到C3烷基基团，可选地具有一个或多个卤素原子或类似物；R10和R11相同或不同，代表一个C1到C6烷基基团，可选地具有一个或多个卤素原子或类似物， 对植物病害有出色的控制效果。
• Sequential and highly stereoselective intermolecular radical additions of 2,3-cis-disubstituted 1,1-dibromo- and 1-bromocyclopropanes to electron-deficient olefins
  作者：Yoo Tanabe、Ken-ichi Wakimura、Yoshinori Nishii

  DOI：10.1016/0040-4039(96)00156-6

  日期：1996.3

  Novel and sequential intermolecular radical additions of 2,3-cis-disubstituted 1,1-dibromo- and 1-bromocyclopropanes to electron-deficient olefins proceeded with high stereoselectivity, i.e., in an exo-face addition manner. This highly stereoselective addition was also applied to an intramolecular cyclization.

  的2,3-新颖和顺序的分子间基加成顺式二取代的1,1-二溴-和1- bromocyclopropanes到高立体选择性的，即，在一个进行缺电子烯烃外型-面加入的方式。这种高度立体选择性的加成也被应用于分子内环化。
• Amidine compound and use thereof
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US09309191B2

  公开（公告）日：2016-04-12

  An amidine compound represented by formula (1) wherein R1, R2, R3, R4 and R5 are the same or different and represent a C1 to C5 alkyl group optionally having one or more halogen atoms or the like; R6 and R7 are a hydrogen atom or the like; R8 and R9 are the same or different and represent a C1 to C3 alkyl group optionally having one or more halogen atoms or the like; and R10 and R11 are the same or different and represent a C1 to C6 alkyl group optionally having one or more halogen atoms or the like, has an excellent control effect on plant diseases.

  一种由式（1）表示的酰胺化合物，其中R1、R2、R3、R4和R5相同或不同，表示具有一个或多个卤素原子或类似物的C1到C5烷基；R6和R7表示氢原子或类似物；R8和R9相同或不同，表示具有一个或多个卤素原子或类似物的C1到C3烷基；R10和R11相同或不同，表示具有一个或多个卤素原子或类似物的C1到C6烷基，对植物病害具有优异的控制效果。
• Khusid, A. Kh.; Sorokina, N. Yu., Journal of Organic Chemistry USSR (English Translation), 1983, vol. 19, p. 235 - 237
  作者：Khusid, A. Kh.、Sorokina, N. Yu.

  DOI：——

  日期：——
• Intramolecular Trapping of Esters by 1-Lithio-1-bromocyclopropanes
  作者：Mark S. Baird、Florian A.M. Huber、Viacheslav V. Tverezovsky、Ivan G. Bolesov

  DOI：10.1016/s0040-4020(00)00385-9

  日期：2000.6

  Reaction of 2-acyloxymethyl-1,1-dibromocyclopropanes with methyllithium at -90 degrees C leads to selective bromine-lithium exchange and intramolecular cyclisation to give a 1-bromo-3-oxabicyclo[3.1.0]hexan-2-ol. (C) 2000 Elsevier Science Ltd. All rights reserved.