N,N',N''-tris(2-carboxyethyl)-1,3,5-benzenetricarboxamide | 87834-25-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N',N''-tris(2-carboxyethyl)-1,3,5-benzenetricarboxamide
• 英文别名: 3-[[3,5-Bis(2-carboxyethylcarbamoyl)benzoyl]amino]propanoic acid
• CAS: 87834-25-1
• 化学式: C₁₈H₂₁N₃O₉
• 分子量: 423.379
• InChiKey: LAWRUNUKENLASU-UHFFFAOYSA-N

物化性质

• 沸点：
  878.5±65.0 °C(Predicted)
• 密度：
  1.443±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  30
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  199
• 氢给体数：
  6
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  N,N',N''-tris(2-carboxyethyl)-1,3,5-benzenetricarboxamide 在 对甲苯磺酸 氢氧化钾 、 盐酸羟胺 作用下， 以 甲醇 为溶剂， 反应 144.0h， 生成 N,N',N''-tris<2-(N-hydroxycarbamoyl)ethyl>-1,3,5-benzenetricarboxamide
  参考文献：
  名称：

  Yoshida, Isao; Murase, Ichiro; Motekaitis, Ramunas J., Canadian Journal of Chemistry, 1983, vol. 61, p. 2740 - 2744

  摘要：

  DOI：
• 作为产物：
  描述：

  均苯三甲酸 在 氢氧化钾 、 氯化亚砜 作用下， 以 乙醚 、 水 为溶剂， 反应 2.0h， 生成 N,N',N''-tris(2-carboxyethyl)-1,3,5-benzenetricarboxamide
  参考文献：
  名称：

  Yoshida, Isao; Murase, Ichiro; Motekaitis, Ramunas J., Canadian Journal of Chemistry, 1983, vol. 61, p. 2740 - 2744

  摘要：

  DOI：

文献信息

• Platelet Aggregation Inhibiting and Anticoagulant Effects of Oligoamines, XVIII: Oligoamines with Fluorescent Properties, Part B: Fluorophores in the Molecular Periphery
  作者：K. Rehse、T. Seidel

  DOI：10.1002/ardp.19943270611

  日期：——

  Seventeen N,N′‐benzene‐1,3‐dimethane and nine N,N′,N″‐benzene‐1,3,5‐trimethane derivatives with fluorescent properties have been synthesized. Three of them show antiplatelet activities (inducer collagen, IC50 Born‐test) in concentrations < 10 μmol/L. They are suitable for interaction studies with biological macromolecules and synthetical and biological membranes. Structure activity relationships demonstrate

  已经合成了 17 种具有荧光特性的 N, N' - 苯 - 1,3 - 二甲烷和九种 N, N ', N ' - 苯 - 1,3,5 - 三甲烷衍生物。其中三个在 <10 μmol / L 的浓度下显示出抗血小板活性（诱导剂胶原蛋白，IC50 Born 测试）。它们适用于与生物大分子以及合成和生物膜的相互作用研究。构效关系表明杂多环荧光团，即喹啉、二苯并呋喃或咔唑是实现此目的的有利替代品。
• COMPOSITION COMPRISING CHELATING AGENTS CONTAINING AMIDOXIME COMPOUNDS
  申请人：Lee Wai Mun

  公开号：US20100105595A1

  公开（公告）日：2010-04-29

  The present invention is a novel aqueous cleaning solution for use in semiconductor front end of the line (FEOL) manufacturing process wherein the cleaning solution comprises at least one amidoxime compound.

  本发明是一种用于半导体前端制造过程中的新型水性清洗溶液，其中清洗溶液包含至少一种酰胺肟化合物。
• COPPER CMP POLISHING PAD CLEANING COMPOSITION COMPRISING OF AMIDOXIME COMPOUNDS
  申请人：Lee Wai Mun

  公开号：US20090137191A1

  公开（公告）日：2009-05-28

  The present invention relates to methods of using amidoxime compositions for cleaning polishing pads, particularly after chemical mechanical planarization or polishing is provided. A polishing pad is cleaned of Cu CMP by-products, subsequent to or during planarizing a wafer, to reduce pad-glazing by applying to the polishing pad surface a composition comprising an aqueous amidoxime compound solution in water.

  本发明涉及使用氨基甲酰肼组合物清洁抛光垫的方法，特别是在化学机械平面化或抛光后提供的方法。在平面化晶片的过程中或之后，通过在抛光垫表面涂布含有水的氨基甲酰肼化合物溶液的组合物，清除铜化学机械抛光副产物，以减少垫面光泽。
• Cleaning method and solution for cleaning a wafer in a single wafer process
  申请人：——

  公开号：US20020102852A1

  公开（公告）日：2002-08-01

  The present invention is a novel cleaning method and a solution for use in a single wafer cleaning process. According to the present invention the cleaning solution comprises ammonium hydroxide (NH 4 OH), hydrogen peroxide (H 2 O 2 ), water (H 2 O) and a chelating agent. In an embodiment of the present invention the cleaning solution also contains a surfactant. And still yet another embodiment of the present invention the cleaning solution also comprises a dissolved gas such as H 2 . In a particular embodiment of the present invention, this solution is used by spraying or dispensing it on a spinning wafer.

  本发明是一种新型清洗方法和溶液，用于单晶片清洗工艺。根据本发明，清洗液包括氢氧化铵（NH 4 OH）、过氧化氢（H 2 O 2 ）、水（H 2 O）和螯合剂。在本发明的一个实施方案中，清洁溶液还含有表面活性剂。本发明的另一个实施方案中，清洁溶液还包含溶解气体，如 H 2 .在本发明的一个特定实施方案中，该溶液通过喷洒或分配到旋转晶片上使用。
• Iron Binding Dendrimers:  A Novel Approach for the Treatment of Haemochromatosis
  作者：Tao Zhou、Hendrik Neubert、Ding Yong Liu、Zu Dong Liu、Yong Min Ma、Xiao Le Kong、Wei Luo、Sykes Mark、Robert C. Hider

  DOI：10.1021/jm0600949

  日期：2006.7.1

  A range of iron binding dendrimers terminated with hexadentate ligands formed from hydroxypyridinone, hydroxypyranone, and catechol moieties have been synthesized in order to investigate their potential as clinically useful iron(III)-selective chelators capable of removing dietary iron from the gastrointestinal tract and preventing the development of iron overload typical of haemochromatosis and thalassaemia intermedia. The iron chelating abilities of these molecules have been characterized by MALDI-TOF mass spectrometry and UV spectrometry. Hydroxypyridinone-terminated dendrimers were found to possess a high affinity and selectivity for iron(III). A hydroxypyridinone-based dendrimer was demonstrated to be highly efficient at reducing the absorption of iron(III) in rat intestine. This family of dendrimers may find an application in the treatment of iron overload.