1-(5-carboxypentyl)-5,6-dichloro-2,3-dimethyl-benzoimidazolium bromide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 1-(5-carboxypentyl)-5,6-dichloro-2,3-dimethyl-benzoimidazolium bromide
• 英文别名: 1-(5-Carboxypentyl)-5,6-Dichloro-2,3-Dimethyl-Benzoimidazolium Bromide；6-(5,6-dichloro-2,3-dimethylbenzimidazol-3-ium-1-yl)hexanoic acid;bromide
• 化学式: Br*C₁₅H₁₉Cl₂N₂O₂
• 分子量: 410.138
• InChiKey: UZUIQYSFCKAEPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.73
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  46.1
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(5-carboxypentyl)-5,6-dichloro-2,3-dimethyl-benzoimidazolium bromide 、 乙二胺 、 三氟乙酸 、 4-丁氧基苯甲醛 生成
  参考文献：
  名称：

  Combinatorial Synthesis of Benzimidazolium Dyes and Its Diversity Directed Application toward GTP-Selective Fluorescent Chemosensors

  摘要：

  Highly selective fluorescence turn-on GTP sensor, GTP Green, was discovered by a diversity directed sensor approach, combined by solid-phase combinatorial synthesis of a benzimidazolium library and high-throughput screening.

  DOI：

  10.1021/ja063733d
• 作为产物：
  描述：

  4,5-二氯邻苯二胺 在 水 、 氢溴酸 、 对甲苯磺酸 、 potassium hydroxide 作用下， 以 二氯甲烷 、 丙酮 、 甲苯 为溶剂， 反应 29.0h， 生成 1-(5-carboxypentyl)-5,6-dichloro-2,3-dimethyl-benzoimidazolium bromide
  参考文献：
  名称：

  Benzimidazolium dyes and their use as fluorescent chemosensors

  摘要：

  本发明涉及以下式(I)的苯并咪唑盐染料化合物：其中，n为2-10的整数，m为2-10的整数，X1和X2分别为卤素，Q为H或树脂，R为(aromatic)o-(linker)p-，其中linker为饱和或不饱和的C1-C5烃链，每个芳香基独立地为取代或未取代的芳香或杂芳基，o为1或2，p为0或1。还公开了制备和使用这些化合物的方法。

  公开号：

  US08716491B2

文献信息

• Benzimidazolium dyes and their use as fluorescent chemosensors
  申请人：Chang Young-Tae

  公开号：US08716491B2

  公开（公告）日：2014-05-06

  The present invention is directed toward benzimidazolium dye compounds of formula (I) as follows: wherein, n is an integer from 2-10, m is an integer from 2-10, X1 and X2 are independently a halogen, Q is H or a resin, and R is (aromatic)o-(linker)p-with the linker being saturated or unsaturated C1-C5 hydrocarbons, each aromatic independently being a substituted or unsubstituted aromatic or heteroaromatic, o being 1 or 2, and p being 0 or 1. Methods of making and using these compounds are also disclosed.

  本发明涉及以下式(I)的苯并咪唑盐染料化合物：其中，n为2-10的整数，m为2-10的整数，X1和X2分别为卤素，Q为H或树脂，R为(aromatic)o-(linker)p-，其中linker为饱和或不饱和的C1-C5烃链，每个芳香基独立地为取代或未取代的芳香或杂芳基，o为1或2，p为0或1。还公开了制备和使用这些化合物的方法。
• BENZIMIDAZOLIUM DYES AND THEIR USE AS FLUORESCENT CHEMOSENSORS
  申请人：CHANG Young-Tae

  公开号：US20080160521A1

  公开（公告）日：2008-07-03

  The present invention is directed toward benzimidazolium dye compounds of formula (I) as follows: wherein, n is an integer from 2-10, m is an integer from 2-10, X 1 and X 2 are independently a halogen, Q is H or a resin, and R is (aromatic) o -(linker) p -with the linker being saturated or unsaturated C 1 -C5 hydrocarbons, each aromatic independently being a substituted or unsubstituted aromatic or heteroaromatic, o being 1 or 2, and p being 0 or 1. Methods of making and using these compounds are also disclosed.

  本发明涉及如下式（I）的苯并咪唑盐染料化合物：其中，n为2-10的整数，m为2-10的整数，X1和X2分别为卤素，Q为氢或树脂，R为（芳香基）o-(连接体)p-，其中连接体为饱和或不饱和的C1-C5烃链，每个芳香基独立地为取代或未取代的芳香基或杂芳香基，o为1或2，p为0或1。同时还公开了制备和使用这些化合物的方法。
• US8716491B2
  申请人：——

  公开号：US8716491B2

  公开（公告）日：2014-05-06
• Combinatorial Synthesis of Benzimidazolium Dyes and Its Diversity Directed Application toward GTP-Selective Fluorescent Chemosensors
  作者：Shenliang Wang、Young-Tae Chang

  DOI：10.1021/ja063733d

  日期：2006.8.1

  Highly selective fluorescence turn-on GTP sensor, GTP Green, was discovered by a diversity directed sensor approach, combined by solid-phase combinatorial synthesis of a benzimidazolium library and high-throughput screening.