(2R,3R)-8-(((2R,3R)-8-(((2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-6-yl)methyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-6-yl)methyl)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate | 1208862-36-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: (2R,3R)-8-(((2R,3R)-8-(((2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-6-yl)methyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-6-yl)methyl)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate
• 英文别名: oolong homobisflavan-trimer 2；[(2R,3R)-8-[[(2R,3R)-8-[[(2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-6-yl]methyl]-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-6-yl]methyl]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
• CAS: 1208862-36-5
• 化学式: C₆₈H₅₄O₃₃
• 分子量: 1399.16
• InChiKey: CXGYUOXMJJLPKV-BVWXBEDUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  101
• 可旋转键数：
  16
• 环数：
  12.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  592
• 氢给体数：
  24
• 氢受体数：
  33

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 (-)-表没食子儿茶素没食子酸酯 在 盐酸 作用下， 以 乙醇 、 水 为溶剂， 反应 4.0h， 生成 oolong homobisflavan-trimer 1 、 (2R,3R)-8-(((2R,3R)-8-(((2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-6-yl)methyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-6-yl)methyl)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate 、 (2R,3R)-8-(((2R,3R)-6-(((2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-6-yl)methyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-8-yl)methyl)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate 、 (2R,2'R,3R,3'R)-8,8'-(2R,2'R,3R,3'R)-8,8'-methylenebis(5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-2-(3,4,5-trihydroxyphenyl)chroman-8,6-diyl)bis(methylene)bis(5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-8,3-diyl) bis(3,4,5-trihydroxybenzoate) 、 oolonghomobisflavan A 、 oolonghomobisflavan B
  参考文献：
  名称：

  GLUCOSYLTRANSFERASE INHIBITOR CONTAINING EPIGALLOCATECHIN GALLATE POLYMER AS ACTIVE INGREDIENT

  摘要：

  公开号：

  EP2330104B1

文献信息

• NOVEL EPIGALLOCATECHIN GALLATE TRIMER AND ALPHA-GLUCOSIDASE INHIBITOR CONTAINING EPIGALLOCATECHIN GALLATE POLYMER
  申请人：Fukui Yuko

  公开号：US20110172300A1

  公开（公告）日：2011-07-14

  The present invention provides an α-glucosidase inhibitor containing a novel epigallocatechin gallate trimer and an epigallocatechin gallate polymer. Decomposition of starch derived from a meal and sugar derived from a polysaccharide can be suppressed by α-glucosidase inhibitory action, thus suppressing absorption. A food and drink excellent in α-glucosidase inhibitory action for suppressing sugar absorption and further for preventing diabetes for a long time can be provided by adding the α-glucosidase inhibitor to a food and drink.

  本发明提供了一种含有新型表没食子酸儿茶素三聚体和表没食子酸儿茶素聚合物的α-葡萄糖苷酶抑制剂。通过α-葡萄糖苷酶抑制作用，可以抑制来源于餐食的淀粉和多糖分解产生的糖的吸收，从而达到抑制吸收的目的。将α-葡萄糖苷酶抑制剂添加到食品和饮料中，可以提供具有优异α-葡萄糖苷酶抑制作用的食品和饮料，进而长期预防糖尿病的发生。
• US8367718B2
  申请人：——

  公开号：US8367718B2

  公开（公告）日：2013-02-05
• GLUCOSYLTRANSFERASE INHIBITOR CONTAINING EPIGALLOCATECHIN GALLATE POLYMER AS ACTIVE INGREDIENT
  申请人：Suntory Holdings Limited

  公开号：EP2330104B1

  公开（公告）日：2017-03-01