ethoxycarbonylmethyltrimethylammonium hydroxide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ethoxycarbonylmethyltrimethylammonium hydroxide
• 英文别名: carbethoxymethyltrimethylammonium hydroxide；(2-Ethoxy-2-oxoethyl)-trimethylazanium;hydroxide；(2-ethoxy-2-oxoethyl)-trimethylazanium;hydroxide
• 化学式: C₇H₁₆NO₂*HO
• 分子量: 163.217
• InChiKey: YELCHWQOEHCLEG-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.08
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  27.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  ethoxycarbonylmethyltrimethylammonium hydroxide 以 水 为溶剂， 生成 甜菜碱
  参考文献：
  名称：

  柔性两性离子分子在溶液中的电荷距离

  摘要：

  DOI：

  10.1021/j100368a013
• 作为产物：
  描述：

  Trimethylammoniumessigsaeurebetain-ethylester-bromid 在 Amberlite IRA₄₀₀ (OH^- form) 作用下， 以 水 为溶剂， 生成 ethoxycarbonylmethyltrimethylammonium hydroxide
  参考文献：
  名称：

  柔性两性离子分子在溶液中的电荷距离

  摘要：

  DOI：

  10.1021/j100368a013

文献信息

• Methods and compositions for reducing ocular discomfort
  申请人：Brien Holden Vision Institute

  公开号：US10085960B2

  公开（公告）日：2018-10-02

  The invention relates to compositions and devices which include an osmolytic agent, in particular a betaine or carnitine compound, for reducing ocular discomfort associated with various diseases or conditions, in particular diseases or conditions associated with high tear film tonicity. The invention also relates to methods of treating or preventing various diseases or conditions using compositions and devices of the invention.

  本发明涉及包括渗透溶解剂，特别是甜菜碱或肉碱化合物的组合物和装置，用于减轻与各种疾病或病症有关的眼部不适，特别是与高泪膜张力有关的疾病或病症。本发明还涉及使用本发明的组合物和装置治疗或预防各种疾病或病症的方法。
• METHODS AND COMPOSITIONS FOR REDUCING OCULAR DISCOMFORT
  申请人：Brien Holden Vision Institute

  公开号：US20150164844A1

  公开（公告）日：2015-06-18

  The invention relates to compositions and devices which include an osmolytic agent, in particular a betaine or carnitine compound, for reducing ocular discomfort associated with various diseases or conditions, in particular diseases or conditions associated with high tear film tonicity. The invention also relates to methods of treating or preventing various diseases or conditions using compositions and devices of the invention.
• [EN] METHODS AND COMPOSITIONS FOR REDUCING OCULAR DISCOMFORT<br/>[FR] MÉTHODES ET COMPOSITIONS RÉDUISANT L'INCONFORT OCULAIRE
  申请人：HOLDEN BRIEN VISION INST

  公开号：WO2013142912A1

  公开（公告）日：2013-10-03

  The invention relates to compositions and devices which include an osmolytic agent, in particular a betaine or carnitine compound, for reducing ocular discomfort associated with various diseases or conditions, in particular diseases or conditions associated with high tear film tonicity. The invention also relates to methods of treating or preventing various diseases or conditions using compositions and devices of the invention.
• Intercharge distance of flexible zwitterionic molecules in solution
  作者：Yves. Chevalier、Pierre. Le Perchec

  DOI：10.1021/j100368a013

  日期：1990.3