diethoxysulfane | 10297-38-8

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机含氧阴离子化合物
• 英文名称: diethoxysulfane
• 英文别名: [(Ethoxysulfanyl)oxy]ethane；ethoxysulfanyloxyethane
• CAS: 10297-38-8
• 化学式: C₄H₁₀O₂S
• 分子量: 122.188
• InChiKey: LXHCUFNVRJLDLN-UHFFFAOYSA-N

物化性质

• 沸点：
  118°C
• 密度：
  0.9940

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  7
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  43.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  diethoxysulfane 生成 sulfoxylic acid
  参考文献：
  名称：

  Goehring, M., Zeitschrift fur anorganische Chemie, 1947, vol. 253, p. 304 - 312

  摘要：

  DOI：
• 作为产物：
  描述：

  Schwefeligsaeurediethylester 在 sodium ethanolate 作用下， 生成 diethoxysulfane
  参考文献：
  名称：

  Surgical Treatment of Severe Acute Pancreatitis: Timing of Operation is Crucial for Survival

  摘要：

  Background: In patients operated on for severe acute pancreatitis (SAP) the impact of the timing of operation on outcome is controversial. Materials and methods: In a retrospective analysis of a prospectively documented database, we studied 250 patients suffering from SAP, who were in need for surgical treatment during their course of disease. Results: From 1982 to 1998, 250 patients with the diagnosis of SAP who required operative treatment were admitted to the intensive care unit (ICU) of a university hospital. The mean APACHE II score on the day of admission was 16.1 (8-35). One hundred eighty-five patients (74%) required reoperation, of whom 111 patients (60%) underwent reoperation on demand and 74 (40%) patients a pre-planned reoperation. Overall mortality was 38.8% (97 patients). In patients who were operated during the first three weeks after onset of disease, mortality was significantly higher than in patients who were operated after three weeks (46% vs. 25%, p < 0.01). Besides patient age (p < 0.05), APACHE II score at admission (p < 0.01), multiple organ dysfunction (p < 0.01), infection of pancreatic necrosis (p < 0.05), surgical control of pancreatic necrosis (p < 0.0001), and the time of surgical intervention (p < 0.05) determined survival significantly. Conclusion: Patients who were operated later than three weeks after onset of disease had a significantly better outcome. In patients suffering from SAP who required surgical treatment, the timing of operation is crucial for survival.

  DOI：

  10.1089/109629603766957004

文献信息

• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: S: MVol.B2, 20.1, page 1011 - 1024
  作者：

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: S: MVol.B2, 10, page 979 - 992
  作者：

  DOI：——

  日期：——
• Birkofer,L.; Niedrig,H., Chemische Berichte, 1966, vol. 99, p. 2070 - 2071
  作者：Birkofer,L.、Niedrig,H.

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: S: MVol.B2, 1.1, page 373 - 396
  作者：

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: S: MVol.B2, 8, page 957 - 969
  作者：

  DOI：——

  日期：——