3-butoxy-1-phenyl-1-propanone | 145628-84-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-butoxy-1-phenyl-1-propanone
• 英文别名: 3-butoxy-1-phenylpropan-1-one；3-butoxy-1-phenyl-propan-1-one；3-Butoxy-1-phenyl-propan-1-on
• CAS: 145628-84-8
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.285
• InChiKey: FQLRMVWGJJHRLO-UHFFFAOYSA-N

物化性质

• 沸点：
  307.1±25.0 °C(Predicted)
• 密度：
  0.9976 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-oxaoctanoyl chloride 生成 3-butoxy-1-phenyl-1-propanone
  参考文献：
  名称：

  Synthesis of Certain 2-Alkoxyethyl Phenyl Ketones

  摘要：

  DOI：

  10.1021/ja01178a065

文献信息

• Synthesis of Alkyl Aryl Ketones by Pd/Light Induced Carbonylative Cross-Coupling of Alkyl Iodides and Arylboronic Acids
  作者：Shuhei Sumino、Takahito Ui、Ilhyong Ryu

  DOI：10.1021/ol401363t

  日期：2013.6.21

  Alkyl aryl ketones were synthesized by the carbonylative cross-coupling reaction of alkyl iodides and arylboronic acids under combined Pd/light conditions. In this reaction, it is likely that an acylpalladium species would be formed via carbonylation of the alkyl radical, which would then undergo transmetalation of an arylboronic acid to give the corresponding acyl(aryl)palladium species, ready to

  烷基芳基酮是通过在碘化钯/轻质条件下烷基碘化物和芳基硼​​酸的羰基交叉偶联反应合成的。在该反应中，很可能通过烷基的羰基化形成酰基铝物种，然后对芳基硼酸进行金属转移，得到相应的酰基（芳基）钯物种，准备进行还原消除以生成烷基。芳基酮。
• Oxa-Michael addition promoted by the aqueous sodium carbonate
  作者：Shi-Huan Guo、Sheng-Zhu Xing、Shuai Mao、Ya-Ru Gao、Wen-Liang Chen、Yong-Qiang Wang

  DOI：10.1016/j.tetlet.2014.10.019

  日期：2014.12

  An efficient Michael addition of alcohols to activated alkenes promoted by sodium carbonate with water as reaction medium has been developed. The reaction provides a general, economical and environmentally friendly approach for the synthesis of beta-alkoxycarbonyl compounds. (C) 2014 Elsevier Ltd. All rights reserved.