琥珀酸二正十六烷基酯 | 4219-53-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 琥珀酸二正十六烷基酯
• 英文名称: Bernsteinsaeure-dicetylester
• 英文别名: Dicetyl succinate；dihexadecyl butanedioate
• CAS: 4219-53-8
• 化学式: C₃₆H₇₀O₄
• 分子量: 566.949
• InChiKey: LMBSJQLSUSUWQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15.4
• 重原子数：
  40
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  hexadecyl hemisuccinate 生成 琥珀酸二正十六烷基酯
  参考文献：
  名称：

  PEG LIPIDS AND USES THEREOF

  摘要：

  本公开部分提供了化合物（即PEG脂质），这些化合物在制药组合物、化妆品组合物和药物递送系统中非常有用，例如用于脂质纳米粒（LNP）配方。本公开还提供了包含此处所述PEG脂质的LNP配方以及使用它们的方法。例如，此处提供的LNP对于将药物（例如治疗药物）递送到主体中非常有用。在某些实施例中，此处提供的PEG脂质和LNP表现出比现有的PEG脂质和LNP配方更高的PEG脱落。

  公开号：

  US20220047518A1

文献信息

• [EN] METALOXYPHTHALOCYANINE COMPOUNDS<br/>[FR] COMPOSES DE METALOXYPHTALOCYANINE
  申请人：AVECIA LTD

  公开号：WO2004020529A1

  公开（公告）日：2004-03-11

  A phthalocyanine compound of Formula (I) wherein M is an oxymetal group, methods and uses involving these compounds.

  一种配方（I）的邻苯二甲酸酞菁化合物，其中M是一个氧化金属基团，涉及这些化合物的方法和用途。
• Detection of Long Alkyl Esters of Succinic and Maleic Acid Using TLC-MALDI-MS
  作者：Hin-Hee Kim、Sang-Pil Han、Jeong-Kwon Kim、Yeong-Joon Kim

  DOI：10.5012/bkcs.2011.32.3.915

  日期：2011.3.20

  Four esters of succinic and maleic acid were synthesized, separated by thin-layer chromatography (TLC), and identified using matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS). A comparison of matrix materials showed that 2,6-dihydroxybenzoic acid (2,6-DHB) yielded a greater ionization efficiency than 2,5-DHB prior to TLC separation. The location of each ester sample on the TLC plate was estimated by comparing the developed plate with a duplicate plate that had been visualized by immersion in a $KMnO_4$ solution. Generally, mass spectra obtained from the $KMnO_4$-visualized plate were relatively poor. Reproducible mass spectra with high peak abundance were difficult to obtain using the 2,6-DHB matrix from crude synthetic esters extracted from the TLC plates. Significant improvements in both reproducibility and sensitivity were realized by using pencil lead as the MALDI matrix. The current methodology will be beneficial to organic chemists since it can provide a guideline for simple and rapid characterization of small organic compounds.

  琥珀酸和马来酸的四种酯被合成、通过薄层色谱法（TLC）分离，并使用基质辅助激光解吸电离质谱法（MALDI-MS）进行鉴定。对基质材料的比较表明，在TLC分离之前，2,6-二羟基苯甲酸（2,6-DHB）的电离效率高于2,5-DHB。通过将展开的TLC板与浸入高锰酸钾溶液后可视化的复制板进行比较，估算了每个酯样品在TLC板上的位置。通常，从高锰酸钾可视化的板上获得的质谱相对较差。使用2,6-DHB基质从TLC板上提取的粗合成酯中难以获得具有高丰度峰的可重复质谱。通过使用铅笔芯作为MALDI基质，显著提高了重复性和灵敏度。当前方法将有利于有机化学家，因为它可以为简单快速地表征小有机化合物提供指导。
• METHOD OF PROVING AUTHENTICITY, SIGNAL CONVERSION METHOD, POLYMER WELDING METHOD, METHOD OF PRODUCING LITHOGRAPHIC PRINTING PLATE, INK FOR PRINTING, TONER, AND HEAT RAY-SHIELDING MATERIAL, EACH USING NAPHTHALOCYANINE COMPOUND, AND METHOD OF PRODUCING NAPHTHALOCYANINE COMPOUND
  申请人：Kimura Keizo

  公开号：US20110311911A1

  公开（公告）日：2011-12-22

  Disclosed is a method of proving the authenticity of goods or a support comprising using a compound represented by Formula (I). wherein, in Formula (I), each of R 11 to R 46 independently represents a hydrogen atom or a substituent group, wherein when a benzene ring is substituted with any of R 11 to R 46 , any groups adjacent to each other among R 11 to R 46 may be bonded each other to form a ring; M represents a hydrogen atom, a metal ion, or a group containing a metal ion; and n represents 1 or 2. The infrared absorption efficiency is high and the deterioration in infrared absorption over time is ameliorated. The infrared absorption efficiency is high and the deterioration in infrared absorption over time is ameliorated.

  公开了一种证明商品真实性或使用包含以式（I）表示的化合物的支持的方法。在式（I）中，R11到R46中的每一个独立地表示氢原子或取代基团，其中当苯环用任何R11到R46中的任何基团取代时，R11到R46中相邻的任何基团可以彼此键合以形成环；M表示氢原子、金属离子或含金属离子的基团；n表示1或2。红外吸收效率高，随时间的推移，红外吸收的恶化得到改善。
• COSMETIC PRODUCT FOR TREATING A KERATIN MATERIAL, COMPRISING A FILM-FORMING AND/OR SETTING CONSTITUENT
  申请人：Henkel AG & Co. KGaA

  公开号：US20220008309A1

  公开（公告）日：2022-01-13

  The application discloses a cosmetic agent for treating a keratinous material comprising a) at least one organic silicon compound and b) polystyrene sulfonate(s), where the cosmetic composition that includes these components improves the fastness properties, in particular UV stability, perspiration fastness and/or wash fastness, of dyed keratinous materials, in particular keratinous fibers.

  该申请公开了一种用于治疗角质素材料的化妆品剂，包括a) 至少一种有机硅化合物和b) 聚苯乙烯磺酸盐，其中包括这些成分的化妆品组合物可以改善染色的角质素材料，特别是角质素纤维的牢度性能，特别是紫外线稳定性，耐汗性和/或耐洗性。
• Metaloxyphthalocyanine compounds
  申请人：Campbell Stanley James

  公开号：US20060000388A1

  公开（公告）日：2006-01-05

  A phthalocyanine compound of Formula (I) wherein M is an oxymetal group, methods and uses involving these compounds.

  一种配方为(I)的酞菁化合物，其中M是一个氧基金属基团，涉及这些化合物的方法和用途。