bis-(3-hydroxy-6-hydroxymethyl-4-oxo-4H-pyran-2-yl)-methane | 2791-12-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: bis-(3-hydroxy-6-hydroxymethyl-4-oxo-4H-pyran-2-yl)-methane
• 英文别名: Bis-(3-hydroxy-6-hydroxymethyl-4-oxo-4H-pyran-2-yl)-methan；2,2'-Methylenebis[3-hydroxy-6-(hydroxymethyl)-4H-pyran-4-one]；3-hydroxy-2-[[3-hydroxy-6-(hydroxymethyl)-4-oxopyran-2-yl]methyl]-6-(hydroxymethyl)pyran-4-one
• CAS: 2791-12-0
• 化学式: C₁₃H₁₂O₈
• 分子量: 296.233
• InChiKey: CWDCRSQPLHDIEC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  134
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  bis-(3-hydroxy-6-hydroxymethyl-4-oxo-4H-pyran-2-yl)-methane 、 乙酸酐 在 硫酸 作用下， 生成 bis-(3-acetoxy-6-acetoxymethyl-4-oxo-4H-pyran-2-yl)-methane
  参考文献：
  名称：

  The Reaction of Kojic Acid with Aldehydes^1,2

  摘要：

  DOI：

  10.1021/ja01274a006
• 作为产物：
  描述：

  曲酸 在 聚合甲醛 作用下， 生成 bis-(3-hydroxy-6-hydroxymethyl-4-oxo-4H-pyran-2-yl)-methane
  参考文献：
  名称：

  The Reaction of Kojic Acid with Aldehydes^1,2

  摘要：

  DOI：

  10.1021/ja01274a006

文献信息

• The Synthesis and Confirmatory Structural Characterisation of Tetradentate Chelators Based on Kojic Acid
  作者：Raymond C. Fox、Paul D. Taylor

  DOI：10.1080/00397919808006861

  日期：1998.5

  Carbon linked tetradentate chelators based on kojic acid were synthesised by a modification of the Mannich reaction. Suppression of the aminomethylation process favours the formation of dimeric, Bakerlite-type structures.
• Bis(5-hydroxy-2-hydroxymethyl-pyran-4-one-6-yl)methane: A novel ligand for the intracellular mobilisation of ferritin-bound iron
  作者：Raymond C. Fox、Paul D. Taylor

  DOI：10.1016/s0960-894x(98)00053-5

  日期：1998.3

  The efficacy of a novel tetradentate iron(III) ligand for the in vitro mobilisation of ferritin-bound iron is measured in direct comparison to the clinically approved agents, 1,2-dimethyl-3-hydroxypyridin-4-one and desferrioxamine. (C) 1998 Elsevier Science Ltd. All rights reserved.
• WASHING AND CLEANING AGENT
  申请人：Henkel AG & Co. KGaA

  公开号：US20160289603A1

  公开（公告）日：2016-10-06

  The present invention relates to the use of bis-pyranonylmethanes in detergents and cleaning agents to improve the washing or cleaning performance in regard to bleachable stains.
• US9714402B2
  申请人：——

  公开号：US9714402B2

  公开（公告）日：2017-07-25
• The Reaction of Kojic Acid with Aldehydes^1,2
  作者：H. N. Barham、G. Nathan Reed

  DOI：10.1021/ja01274a006

  日期：1938.7