tetra-N-acetylchitotetraose

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: tetra-N-acetylchitotetraose
• 英文别名: 2-acetamido-2-deoxy-D-gluco-hexopyranosyl-(1->4)-2-acetamido-2-deoxy-D-gluco-hexopyranosyl-(1->4)-2-acetamido-2-deoxy-D-gluco-hexopyranosyl-(1->4)-2-acetamido-2-deoxy-D-gluco-hexopyranose；N-[(3R,4R,5S,6R)-5-[(3R,4R,5S,6R)-3-acetamido-5-[(3R,4R,5S,6R)-3-acetamido-5-[(3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,4-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
• 化学式: C₃₂H₅₄N₄O₂₁
• 分子量: 830.795
• InChiKey: PFZKWTWCVGDJQC-BRKSNAHYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -9
• 重原子数：
  57
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  383
• 氢给体数：
  14
• 氢受体数：
  21

反应信息

• 作为反应物：
  描述：

  尿苷(5')二氢二磷酰(1)-alpha-D-葡萄糖 、 tetra-N-acetylchitotetraose 在 sodium cacodylate buffer 、 manganese(ll) chloride 作用下， 反应 72.0h， 以22%的产率得到4'''-O-(β-D-glucopyranosyl)-tetra-N-acetylchitotetraose
  参考文献：
  名称：

  β-Glucosylation of chitooligomers by galactosyltransferase

  摘要：

  Galactosyltransferase from bovine milk was found to be able to utilise UDP-Glc to transfer Glc onto GlcNAc and chitooligomers [-beta-GlcNAc-(1-->4)-](n), n=2-4. beta-Glucosylated products were used in binding studies with NKR-P1A protein cloned from rat natural killer cells. (C) 1998 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00248-6