1-[(6-carboxylethylthio-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-[(6-carboxylethylthio-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine
• 英文别名: 3-[5-(2-Nitroiminoimidazolidin-1-ylmethyl)-2-pyridylthio]propionic acid；3-[5-[(2-nitroiminoimidazolidin-1-yl)methyl]pyridin-2-yl]sulfanylpropanoic acid
• 化学式: C₁₂H₁₅N₅O₄S
• 分子量: 325.348
• InChiKey: SXOZFXITZRENEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  149
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  3-巯基丙酸 、 吡虫啉 在 氢氧化钾 作用下， 以 二甲基亚砜 为溶剂， 反应 1.0h， 以45%的产率得到1-[(6-carboxylethylthio-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine
  参考文献：
  名称：

  Development of an Enzyme-Linked Immunosorbent Assay for the Insecticide Imidacloprid

  摘要：

  Enzyme-linked immunosorbent assays (ELISAs) were developed for imidacloprid, a neonicotinoid insecticide. Haptens were designed in such ways that spacer arms were introduced on either the pyridinyl or the imidazolidinyl ring of imidacloprid. Two sets of polyclonal antibodies were raised from rabbits immunized with two different immunogens and were characterized with an indirect ELISA format. Cross-reactivities and effects of organic solvents on the assays were evaluated. One set of antibodies shows approximately equal cross-reactivities to imidacloprid and its major metabolites with half-maximum inhibition concentrations (I-50) Of 73-88 ppb. Another is specific to imidacloprid with an I-50 of 35 ppb. The assay was initially applied to the analysis of imidacloprid in fortified water, coffee cherry, and bean extracts.

  DOI：

  10.1021/jf991257n

文献信息

• KIT FOR MEASUREMENT OF TERMITE INSECTICIDE ACTIVE INGREDIENT BY IMMUNOASSAY METHOD
  申请人：Miyake Shiro

  公开号：US20100047927A1

  公开（公告）日：2010-02-25

  A kit and a method are provided for easily measuring the concentration of an active ingredient of a termite insecticide persisting in soil, particularly on site where a termite insecticide was actually applied. A kit of the present invention comprises 1) an extraction unit for extracting, with an solvent, a termite insecticide active ingredient from an object of measurement and 2) a reaction unit including a reaction container for encapsulating an identifying antigen, a fixing member for immobilizing an antibody against an active ingredient, and a sealing member capable of fitting to the reaction container. The kit optionally includes 3) a detection unit for visually or optically detecting a change depending on the concentrations of the active ingredient in the object of measurement, and 4) a dilution unit for diluting the sample solution to a certain ratio.

  本发明提供了一种套件和方法，用于在土壤中测量白蚁杀虫剂中活性成分的浓度，特别是在实际应用了白蚁杀虫剂的现场。本发明的套件包括1）提取单元，用溶剂从测量对象中提取白蚁杀虫剂活性成分和2）反应单元，包括一个反应容器，用于封装识别抗原，一个固定成员，用于固定针对活性成分的抗体，以及一个能够适配到反应容器的密封成员。该套件可选地包括3）检测单元，用于可视或光学检测取样中活性成分浓度的变化，并且4）稀释单元，用于将样品溶液稀释到一定比例。
• Kit for measurement of termite insecticide active ingredient by immunoassay method
  申请人：Bayer Cropscience AG

  公开号：US08323904B2

  公开（公告）日：2012-12-04

  A kit and a method are provided for easily measuring the concentration of an active ingredient of a termite insecticide persisting in soil, particularly on site where a termite insecticide was actually applied. A kit of the present invention comprises 1) an extraction unit for extracting, with an solvent, a termite insecticide active ingredient from an object of measurement and 2) a reaction unit including a reaction container for encapsulating an identifying antigen, a fixing member for immobilizing an antibody against an active ingredient, and a sealing member capable of fitting to the reaction container. The kit optionally includes 3) a detection unit for visually or optically detecting a change depending on the concentrations of the active ingredient in the object of measurement, and 4) a dilution unit for diluting the sample solution to a certain ratio.

  本发明提供了一种用于在土壤中测量白蚁杀虫剂活性成分浓度的简便工具和方法，特别是在实际应用白蚁杀虫剂的现场。本发明的工具包括：1）用于使用溶剂从测量对象中提取白蚁杀虫剂活性成分的提取单元；2）包括反应容器用于封装识别抗原、用于固定抗活性成分的抗体的固定成员和能够适配于反应容器的密封成员的反应单元。该工具包还可选地包括：3）用于视觉或光学检测测量对象中活性成分浓度变化的检测单元；以及4）用于将样品溶液稀释到一定比例的稀释单元。
• KIT FOR ASSAYING ACTIVE INGREDIENT OF TERMITE CONTROLLING AGENT BY USING IMMUNOASSAY METHOD
  申请人：HORIBA, LTD.

  公开号：EP1965209A1

  公开（公告）日：2008-09-03

  A kit and a method are provided for easily measuring the concentration of an active ingredient of a termite insecticide persisting in soil, particularly on site where a termite insecticide was actually applied. A kit of the present invention comprises 1) an extraction unit for extracting, with an solvent, a termite insecticide active ingredient from an object of measurement and 2) a reaction unit including a reaction container for encapsulating an identifying antigen, a fixing member for immobilizing an antibody against an active ingredient, and a sealing member capable of fitting to the reaction container. The kit optionally includes 3) a detection unit for visually or optically detecting a change depending on the concentrations of the active ingredient in the object of measurement, and 4) a dilution unit for diluting the sample solution to a certain ratio.

  本发明提供了一种试剂盒和一种方法，可以方便地测量土壤中白蚁杀虫剂活性成分的浓度，特别是在实际施用白蚁杀虫剂的现场。本发明的试剂盒包括：1）提取单元，用于用溶剂从测量对象中提取白蚁杀虫剂活性成分；2）反应单元，包括用于封装识别抗原的反应容器、用于固定针对活性成分的抗体的固定部件，以及能够与反应容器相配合的密封部件。试剂盒还可选择包括：3）一个检测单元，用于根据测量对象中活性成分的浓度变化进行视觉或光学检测；4）一个稀释单元，用于将样品溶液稀释到一定比例。
• JP2000191698A
  申请人：——

  公开号：JP2000191698A

  公开（公告）日：2000-07-11
• US8323904B2
  申请人：——

  公开号：US8323904B2

  公开（公告）日：2012-12-04