1-hexadecyl <(1-hexadecyl 2,3,4-tri-O-acetyl-6-deoxy-α-D-gluco-heptopyranosyluronate)-2,3,4-tri-O-acetyl-6-deoxy-α-D-gluco-heptopyranosid>uronate | 132627-81-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1-hexadecyl <(1-hexadecyl 2,3,4-tri-O-acetyl-6-deoxy-α-D-gluco-heptopyranosyluronate)-2,3,4-tri-O-acetyl-6-deoxy-α-D-gluco-heptopyranosid>uronate
• 英文别名: hexadecyl 2-[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(2-hexadecoxy-2-oxoethyl)oxan-2-yl]oxyoxan-2-yl]acetate
• CAS: 132627-81-7
• 化学式: C₅₈H₉₈O₁₉
• 分子量: 1099.4
• InChiKey: BTKIIZNEMDFUSF-RQQDWODESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.87
• 重原子数：
  77.0
• 可旋转键数：
  42.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  238.09
• 氢给体数：
  0.0
• 氢受体数：
  19.0

反应信息

• 作为反应物：
  描述：

  1-十六烷醇 、 1-hexadecyl <(1-hexadecyl 2,3,4-tri-O-acetyl-6-deoxy-α-D-gluco-heptopyranosyluronate)-2,3,4-tri-O-acetyl-6-deoxy-α-D-gluco-heptopyranosid>uronate 在 对甲苯磺酸 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 96.0h， 以31%的产率得到1-hexadecyl <(1-hexadecyl 6-deoxy-α-D-gluco-heptopyranosyluronate)-6-deoxy-α-D-gluco-heptopyranosid>uronate
  参考文献：
  名称：

  Synthesis of alkyl [(alkyl 6-deoxy-α-d-gluco-heptopyranosyl-uronate) 6-deoxy-α-d-gluco-heptopyranosid]uronates, a novel type of mirror pseudo cord factor

  摘要：

  The 1-octyl, 1-pentadecyl, 1-hexadecyl, 1-heptadecyl, and 1-octadecyl diesters of (6-deoxy-alpha-D-gluco-heptopyranosyluronic acid) 6-deoxy-alpha-D-gluco-heptopyranosiduronic acid, a new homolog of trehalosuronic acid, were prepared by two procedures. One procedure involved conversion of the peracetylated acid into its dichloride, reaction of the latter with the alkanols, and acid-catalyzed deacetylation of the products, whereas the other consisted of reaction of alkyl mesylates with the potassium salt of the unprotected acid.

  DOI：

  10.1016/0008-6215(91)80155-g
• 作为产物：
  描述：

  2-[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(carboxymethyl)oxan-2-yl]oxyoxan-2-yl]acetic acid 在 草酰氯 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 3.58h， 生成 1-hexadecyl <(1-hexadecyl 2,3,4-tri-O-acetyl-6-deoxy-α-D-gluco-heptopyranosyluronate)-2,3,4-tri-O-acetyl-6-deoxy-α-D-gluco-heptopyranosid>uronate
  参考文献：
  名称：

  Synthesis of alkyl [(alkyl 6-deoxy-α-d-gluco-heptopyranosyl-uronate) 6-deoxy-α-d-gluco-heptopyranosid]uronates, a novel type of mirror pseudo cord factor

  摘要：

  The 1-octyl, 1-pentadecyl, 1-hexadecyl, 1-heptadecyl, and 1-octadecyl diesters of (6-deoxy-alpha-D-gluco-heptopyranosyluronic acid) 6-deoxy-alpha-D-gluco-heptopyranosiduronic acid, a new homolog of trehalosuronic acid, were prepared by two procedures. One procedure involved conversion of the peracetylated acid into its dichloride, reaction of the latter with the alkanols, and acid-catalyzed deacetylation of the products, whereas the other consisted of reaction of alkyl mesylates with the potassium salt of the unprotected acid.

  DOI：

  10.1016/0008-6215(91)80155-g

文献信息

• BAER, HANS H.;BRETON, ROGER L., CARBOHYDR. RES., 209,(1991) C. 181-189
  作者：BAER, HANS H.、BRETON, ROGER L.

  DOI：——

  日期：——