N-(3-bromo-2-fluorophenyl)-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide | 1357587-46-2
中文名称
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中文别名
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英文名称
N-(3-bromo-2-fluorophenyl)-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide
英文别名
——
CAS
1357587-46-2
化学式
C14H11BrF3NO3S
mdl
——
分子量
410.211
InChiKey
MTVDLHWQIKSRBH-UHFFFAOYSA-N
BEILSTEIN
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EINECS
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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沸点：456.7±55.0 °C(Predicted)
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密度：1.648±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
计算性质
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辛醇/水分配系数(LogP)：3.6
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重原子数：23
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可旋转键数：5
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环数：2.0
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sp3杂化的碳原子比例：0.14
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拓扑面积：55
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氢给体数：0
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氢受体数：7
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— N-(3-bromo-2-fluorophenyl)-2,5-difluorobenzenesulfonamide 1357587-45-1 C12H7BrF3NO2S 366.158 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— N-(3-acetyl-2-fluorophenyl)-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 1394938-63-6 C16H14F3NO4S 373.353 —— N-[3-(bromoacetyl)-2-fluorophenyl]-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 1394938-92-1 C16H13BrF3NO4S 452.249 —— N-[3-(1-butoxyethenyl)-2-fluorophenyl]-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 1394938-67-0 C20H22F3NO4S 429.46 —— 2,5-difluoro-N-(2-fluoro-3-{1-[(trimethylsilyl)oxy]ethenyl}phenyl)-N-(methoxymethyl)benzenesulfonamide 1394938-95-4 C19H22F3NO4SSi 445.535 —— 2,5-difluoro-N-[2-fluoro-3-(2H-pyrazol-3-yl)-phenyl]-N-methoxymethylbenzenesulfonamide 1357587-48-4 C17H14F3N3O3S 397.378 —— 3-{[(2,5-difluorophenyl)sulfonyl](methoxymethyl)amino}-2-fluoro-N-methoxy-N-methylbenzamide 1394938-68-1 C17H17F3N2O5S 418.394 —— 2,5-difluoro-N-{2-fluoro-3-[(2-chloropyridin-4-yl)acetyl]phenyl}-N-(methoxymethyl)benzenesulfonamide 1394939-42-4 C21H16ClF3N2O4S 484.883 —— N-[3-(4-bromo-1H-pyrazol-3-yl)-2-fluorophenyl]-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357587-49-5 C17H13BrF3N3O3S 476.274 —— N-[3-(2-amino-1,3-thiazol-4-yl)-2-fluorophenyl]-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 1394938-97-6 C17H14F3N3O3S2 429.444 —— N-[3-(2-amino-5-bromo-1,3-thiazol-4-yl)-2-fluorophenyl]-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 1394938-99-8 C17H13BrF3N3O3S2 508.34 —— N-[3-(4-bromo-1-isopropyl-3H-pyrazol-3-yl)-2-fluorophenyl]-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357587-50-8 C20H19BrF3N3O3S 518.354 —— 2,5-difluoro-N-[2-fluoro-3-(1-isopropyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenyl]-N-methoxymethylbenzenesulfonamide 1357587-59-7 C25H23F3N4O3S 516.544 —— 2,5-difluoro-N-{2-fluoro-3-[1-(2-hydroxyethyl)-4-pyridin-4-yl-1H-pyrazol-3-yl]phenyl}-N-methoxymethylbenzenesulfonamide 1357588-05-6 C24H21F3N4O4S 518.516 —— N-(3-{4-bromo-1-[2-(tetrahydropyran-2-yloxy)ethyl]-1H-pyrazol-3-yl}-2-fluorophenyl)-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357588-03-4 C24H25BrF3N3O5S 604.445 —— N-{3-[5-bromo-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 1394939-75-3 C22H20BrF3N2O4S2 577.443 2,5-二氟-N-{2-氟-3-[2-(四氢吡喃-2-基)-2H-吡唑-3-基]苯基}-N-甲氧基甲基苯磺酰胺 2,5-difluoro-N-{2-fluoro-3-[2-(tetrahydropyran-2-yl)-2H-pyrazol-3-yl]phenyl}-N-methoxymethylbenzenesulfonamide 1357587-47-3 C22H22F3N3O4S 481.496 —— 2,5-difluoro-N-[2-fluoro-3-(1-piperidin-4-yl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenyl]-N-methoxymethylbenzenesulfonamide 1357587-69-9 C27H26F3N5O3S 557.596 —— 2,5-difluoro-N-(2-fluoro-3-{4-pyridin-4-yl-1-[2-(tetrahydropyran-2-yloxy)ethyl]-1H-pyrazol-3-yl}phenyl)-N-methoxymethylbenzenesulfonamide 1357588-04-5 C29H29F3N4O5S 602.634 —— 2,5-difluoro-N-{2-fluoro-3-[1-(1-methylpiperidin-4-yl)-4-pyridin-4-yl-1H-pyrazol-3-yl]phenyl}-N-methoxymethylbenzenesulfonamide 1357587-70-2 C28H28F3N5O3S 571.623 —— 4-(4-bromo-3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}pyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 1357587-65-5 C27H30BrF3N4O5S 659.524 —— N-{3-[1-(1-acetylpiperidin-4-yl)-4-pyridin-4-yl-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357587-71-3 C29H28F3N5O4S 599.634 —— N-{3-[4-(2-cyanopyridin-4-yl)-1-(tetrahydropyran-4-yl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357588-18-1 C28H24F3N5O4S 583.591 —— N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1-piperidin-4-yl-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357587-98-4 C31H35F3N6O3S 628.719 —— N-{3-[4-(2-cyanopyridin-4-yl)-1-(1-methylpiperidin-4-yl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357588-21-6 C29H27F3N6O3S 596.633 —— N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1-(1-methylpiperidin-4-yl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357587-99-5 C32H37F3N6O3S 642.745 —— N-{3-[4-(2-aminopyrimidin-4-yl)-1-isopropyl-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357587-74-6 C24H23F3N6O3S 532.546 —— 2,5-difluoro-N-{2-fluoro-3-[1-isopropyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazol-3-yl]phenyl}-N-methoxymethylbenzenesulfonamide 1357587-72-4 C26H31BF3N3O5S 565.421 —— N-{3-[1-(1-acetylpiperidin-4-yl)-4-(2-tert-butylaminopyridin-4-yl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 1357588-00-1 C33H37F3N6O4S 670.756 —— 4-(3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}-4-pyridin-4-ylpyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 1357587-67-7 C32H34F3N5O5S 657.714 —— 4-[3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}-4-(1-oxypyridin-4-yl)pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester 1357587-96-2 C32H34F3N5O6S 673.713 —— 2,5-difluoro-N-{2-fluoro-3-[5-(3-fluoropyridin-4-yl)-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-4-yl]phenyl}-N-(methoxymethyl)benzenesulfonamide 1394939-77-5 C27H23F4N3O4S2 593.623 —— 4-(4-(2-cyanopyridin-4-yl)-3-{3-[(2,5-difluorobenzenesulfonyl)methoxymethylamino]-2-fluorophenyl}pyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 1357588-20-5 C