乙二胺-N,N-乙二酸-N,N-二丙酸 | 32701-19-2

• 物质功能分类: 化学试剂 - 有机试剂 - 多胺
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 乙二胺-N,N-乙二酸-N,N-二丙酸
• 中文别名: 乙二胺二乙酸二丙酸；乙二胺-N,N'-二乙酸基-N,N'-二丙酸水合物；乙二胺-N,N'-乙二酸-N,N'-二丙酸；乙二胺-N,N'-二乙酸基-N,N'-二丙酸
• 英文名称: ethylenediamine-N,N′-diacetic-N,N′-di-3-propionic acid
• 英文别名: ethylenediamine-N,N'-diacetate-N,N'-di-3-propionate；Ethylendiamin-N,N'-diessigsaeure-N,N'-dipropionsaeure；ethylenediamine-N,N'-diacetic-N,N'-di-3-propionic acid；ethylenediamine-N,N'-diacetic acid-N,N'-dipropionic acid；N,N'-Bis-(2-carboxy-aethyl)-N,N'-bis-carboxymethyl-aethylendiamin；N,N'-bis-carboxymethyl-N,N'-ethanediyl-di-β-alanine；N,N'-Bis-carboxymethyl-N,N'-aethandiyl-di-β-alanin；N,N'-bis(2-carboxyethyl)-N,N'-ethylenediglycine；H4eddadp；N,N'-bis(2-carboxyethyl)-N,N'ethylenediglycine trihydrate；ethylenediamine-N,N'-diacetic-N,N'-dipropionic acid；3-[2-[2-carboxyethyl(carboxymethyl)amino]ethyl-(carboxymethyl)amino]propanoic acid
• CAS: 32701-19-2
• 化学式: C₁₂H₂₀N₂O₈
• mdl: MFCD00002768
• 分子量: 320.299
• InChiKey: IZQWNOQOAFSHOK-UHFFFAOYSA-N

物化性质

• 熔点：
  183-184 °C(lit.)
• 沸点：
  621.1±55.0 °C(Predicted)
• 密度：
  1.458±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于二甲基亚砜、甲醇
• 稳定性/保质期：

  如果按照规格使用和储存，则不会分解，未有已知危险反应。

计算性质

• 辛醇/水分配系数(LogP)：
  -6.1
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.666
• 拓扑面积：
  156
• 氢给体数：
  4
• 氢受体数：
  10

安全信息

• WGK Germany：
  3
• 海关编码：
  2922509090
• 储存条件：
  请将贮藏器密封，并将其存放在阴凉、干燥处。确保工作环境具有良好的通风或排气设施。

SDS

Ethylenediamine-N,N'-diacetic-N,N'-dipropionic Acid Revision number: 5
Hydrate
SAFETY DATA SHEET

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Section 1. IDENTIFICATION
Product name: Ethylenediamine-N,N'-diacetic-N,N'-dipropionic Acid Hydrate

Revision number: 5

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Section 2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDS Not classified
Not classified
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS Not classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols None
Signal word No signal word
Hazard statements None
Precautionary statements: None

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance
Substance/mixture:
Components: Ethylenediamine-N,N'-diacetic-N,N'-dipropionic Acid Hydrate
>98.0%(T)
Percent:
CAS Number: 32701-19-2
Chemical Formula: C12H20N2O8·xH2O

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Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Remove/Take off immediately all contaminated clothing. Rinse skin with
Skin contact:
water/shower. If skin irritation or rash occurs: Get medical advice/attention.
Rinse cautiously with water for several minutes. Remove contact lenses, if present
Eye contact:
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion: Get medical advice/attention if you feel unwell. Rinse mouth.
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

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Section 5. FIRE-FIGHTING MEASURES
Suitable extinguishing Dry chemical, foam, water spray, carbon dioxide.
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
generate poisonous fume.
from the chemical:
Acid Hydrate

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Section 5. FIRE-FIGHTING MEASURES
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

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Section 6. ACCIDENTAL RELEASE MEASURES
Use personal protective equipment. Keep people away from and upwind of spill/leak.
Personal precautions,
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Handling is performed in a well ventilated place. Wear suitable protective equipment.
Technical measures:
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions: Keep container tightly closed. Store in a cool and dark place.
Store away from incompatible materials such as oxidizing agents.
Packaging material: Comply with laws.

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Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Install a closed system or local exhaust as possible so that workers should not be
Engineering controls:
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection: Protective gloves.
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Solid
Form: Crystal- Powder
White - Almost white
Colour:
Odour: No data available
pH: No data available
Melting point/freezing point:No data available
No data available
Boiling point/range:
Flash point: No data available
Flammability or explosive
limits:
No data available
Lower:
Upper: No data available
No data available
Relative density:
Solubility(ies):
No data available
[Water]
[Other solvents] No data available
Acid Hydrate

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Section 10. STABILITY AND REACTIVITY
Chemical stability: Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx)
products:

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Section 11. TOXICOLOGICAL INFORMATION
No data available
Acute Toxicity:
Skin corrosion/irritation: No data available
No data available
Serious eye
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
No data available
IARC =
NTP = No data available
No data available
Reproductive toxicity:

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Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence / degradability: No data available
Bioaccumulative No data available
potential(BCF):
Mobility in soil
Log Pow: No data available
Soil adsorption (Koc): No data available
Henry's Law No data available
constant(PaM3/mol):

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Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

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Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not listed

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Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.
Acid Hydrate

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  乙二胺-N,N-乙二酸-N,N-二丙酸 、 nickel dichloride 在 氢氧化钾 作用下， 以 水 为溶剂， 生成 ethylenediamine-N,N'-diacetato-N,N'-dipropionatonickelate(II)
  参考文献：
  名称：

  Evidence for some pentadentate coordination in ethylenediamine-N,N′-diacetato-N,N′-di-3-propionatonickelate(II)

  摘要：

  DOI：

  10.1016/s0020-1693(00)84673-3
• 作为产物：
  描述：

  聚合甲醛 、 氰化钠 、 ethylenediaminedipropionic acid dihydrochloride 生成 乙二胺-N,N-乙二酸-N,N-二丙酸
  参考文献：
  名称：

  的一些衍生物NN '-biscarboxymethyl-和NN ' -双（β羧乙基） -乙二胺

  摘要：

  的一些新的衍生物的制备方法NN '-biscarboxymethyl-和NN ' -双（β羧乙基） -亚乙基-二胺（VII）和（XVIII）]进行说明。用甲醛处理后一种化合物的双酰胺，得到1，2-双-（4-氧六氢-1-嘧啶基）乙烷（XXII）。在由相应的低产率得到氨基酸（VII）的双酰胺NN '二苄双酰胺; 通过该系列中容易形成内酰胺的方法，可以防止由（VII）直接制备。当用氰酸钾处理时，氨基酸（VII）和（XVIII）分别得到1,2-双-（2,4-二氧杂咪唑啉-1-基）乙烷（XI）和1,2-双（2， 4-二氧六氢-1-嘧啶基）乙烷（XXIII）。

  DOI：

  10.1039/j39710002389

文献信息

• COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS
  申请人：Chodorowski-Kimmes Sandrine

  公开号：US20100239509A1

  公开（公告）日：2010-09-23

  The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups; of a monocarboxylic acid containing 6 to 32 carbon atoms; of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and (b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

  本专利申请涉及一种化妆品或皮肤科学组合物，包括在化妆品或皮肤科学上可接受的介质中，包含以下聚合物的组合物：(a) 由以下反应得到的聚合物骨架：含有3至6个羟基的多元醇；含有6至32个碳原子的一元羧酸；至少含有两个羧基COOH的多元羧酸，和/或类似多元羧酸的环酐和/或至少含有一个羧基COOH的内酯；以及(b) 至少一个连接到所述聚合物骨架的连接基团，并能够与一个或多个配对连接基团建立H键，每个连接基团的配对涉及至少三个H（氢）键。该专利申请还涉及使用所述组合物的化妆品处理过程。
• COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION
  申请人：GIUSTINIANI Pascal

  公开号：US20090028807A1

  公开（公告）日：2009-01-29

  The present application relates to a cosmetic or pharmaceutical, in particular lipstick, composition comprising a polycondensate The application also relates to a method of cosmetic treatment using the composition, the polycondensate thus defined and a method of preparing the polycondensate.

  本申请涉及一种化妆品或药用品，特别是口红，包括聚缩酸酯的组合物。该申请还涉及一种使用该组合物进行化妆处理的方法，所述聚缩酸酯的定义以及一种制备聚缩酸酯的方法。
• COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT
  申请人：Malle Gerard

  公开号：US20100272660A1

  公开（公告）日：2010-10-28

  The present application relates to a cosmetic or pharmaceutical composition comprising a polycondensate capable of being obtained by the reaction of the following monomers alone: of 10 to 30% by weight, relative to the total weight of the polycondensate, of one or more polyols comprising 3 to 6 hydroxyl groups; of 30 to 80% by weight, relative to the total weight of the polycondensate, of one or more linear, branched and/or cyclic, saturated or unsaturated, non-aromatic monocarboxylic acids comprising 6 to 32 carbon atoms; of 1 to 40% by weight, relative to the total weight of the polycondensate, of one or more polycarboxylic acids and/or cyclic anhydrides of such a polycarboxylic acid and/or lactones comprising at least one COOH group; and optionally of 0.1 to 15% by weight, relative to the total weight of the polycondensate, of one or more silicones having a hydroxyl and/or carboxyl functional group. The application also relates to a method of cosmetic treatment using the said composition, and the polycondensate thus defined.

  本申请涉及一种化妆品或药用组合物，包括由以下单体反应而得的聚缩酸酯：相对于聚缩酸酯的总重量，占10至30%的一种或多种含有3至6个羟基的多元醇；占30至80%的一种或多种线性、支链和/或环状、饱和或不饱和、非芳香族的单羧酸，含有6至32个碳原子；占聚缩酸酯总重量的1至40%的一种或多种多羧酸和/或多羧酸的环状酐和/或含有至少一个COOH基团的内酯；以及可选地占聚缩酸酯总重量的0.1至15%的一种或多种硅氧烷，具有羟基和/或羧基官能团。该申请还涉及使用所述组合物进行化妆处理的方法，以及如此定义的聚缩酸酯。
• Synthetic, Crystallographic, and Computational Study of Copper(II) Complexes of Ethylenediaminetetracarboxylate Ligands
  作者：Zoran D. Matović、Vesna D. Miletić、Marina Ćendić、Auke Meetsma、Petra J. van Koningsbruggen、Robert J. Deeth

  DOI：10.1021/ic301609t

  日期：2013.2.4

  Ba[Cu(eddadp)]·8H2O is proposed to adopt a trans(O5) geometry (two axial acetates) on the basis of density functional theory calculations and comparisons of IR and UV–vis spectral data. Experimental and computed structural data correlating similar copper(II) chelate complexes have been used to better understand the isomerism and departure from regular octahedral geometry within the series. The in-plane O–Cu–N chelate

  六齿乙二胺四羧酸型配体H 4 eda3p和H 4 eddadp（H 4 eda3p =乙二胺-N-乙酸-N，N '，N'-三-3-丙酸; H 4 eddadp =乙二胺ñ，ñ '-diacetic- ñ，ñ ' -二-3-丙酸）已经制备。Ba [Cu（eda3p）]·8H 2 O化合物在晶体学上已经建立了八面体反式（O 6）几何结构（两个丙酸酯配体在轴向位置上协调），而Ba [Cu（eddadp）]·8H 2O基于密度泛函理论计算以及红外和紫外-可见光谱数据的比较，建议采用反式（O 5）几何结构（两个轴向乙酸盐）。与相似的铜（II）螯合物配合使用的实验和计算结构数据已被用来更好地理解该异构现象以及该系列中规则八面体几何结构的偏离。对于具有两个赤道β-丙酸酯环的eddadp络合物，面内O-Cu-N螯合角显示出与理想八面体值90°的偏差最小，因此应变最小。已经建立了四方性和五元环数量之间的线性
• Functionalized Photoinitiators
  申请人：Dietliker Kurt

  公开号：US20080021126A1

  公开（公告）日：2008-01-24

  The invention relates to novel photoinitiators of formula (I) wherein each of the substituents is given the definition as set forth in the Specification and the claims. The photoinitiators can be used to prepare multifunctional photoinitiators.

  该发明涉及公式（I）中的新型光引发剂，其中每个取代基的定义如规范和索赔中所述。这些光引发剂可用于制备多功能光引发剂。

表征谱图