2-(9-anthracenyl)propanoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 2-(9-anthracenyl)propanoic acid
• 英文别名: 2-(9-anthryl)propanoic acid；2-(Anthracen-9-yl)propanoic acid；2-anthracen-9-ylpropanoic acid
• 化学式: C₁₇H₁₄O₂
• 分子量: 250.297
• InChiKey: JVLRJYDOJMOUNK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(9-anthracenyl)propanoic acid 在 human serum albumin 作用下， 以 正己烷 、 甲基叔丁基醚 、 溶剂黄146 为溶剂， 生成 蒽醌
  参考文献：
  名称：

  Stereodifferentiation in the Compartmentalized Photooxidation of a Protein-Bound Anthracene

  摘要：

  Encapsulation within transport proteins strongly reduces the photooxidation rate of (S)- and (R)-2-(9-anthracenyl)propanoic acid (1) and results in a significant stereodifferentiation. The most remarkable effects are observed within human serum albumin (HSA).

  DOI：

  10.1021/ol201209h
• 作为产物：
  描述：

  methyl α-methyl-10-anthraceneacetate 在 水 、 potassium hydroxide 作用下， 反应 2.0h， 以92%的产率得到2-(9-anthracenyl)propanoic acid
  参考文献：
  名称：

  Stereodifferentiation in the Compartmentalized Photooxidation of a Protein-Bound Anthracene

  摘要：

  Encapsulation within transport proteins strongly reduces the photooxidation rate of (S)- and (R)-2-(9-anthracenyl)propanoic acid (1) and results in a significant stereodifferentiation. The most remarkable effects are observed within human serum albumin (HSA).

  DOI：

  10.1021/ol201209h

文献信息

• Sulfonium salt compound
  申请人：——

  公开号：US20040033434A1

  公开（公告）日：2004-02-19

  A compound shown by the general formula [1] 1 (wherein R 1 , R 2 and R 3 are each independently an aromatic hydrocarbon residual group, Y n− is an anion derived from a carboxylic acid having 3 or more carbon atoms with substituted fluorine atoms, and n is 1 or 2, provided that R 1 , R 2 and R 3 each is not a phenyl group having substituents at an ortho and/or a meta position), and a composition consisting of the compound and a diazodisulfone compound are disclosed. Use of the compound or the compound as an acid generator for resists produces the effects of improving the profiles of ultra-fine patterns or diminishing sidewall irregularities in ultra-fine patterns. The compound is also useful as a cationic photopolymerization initiator.

  公式为[1]1的化合物被展示出来（其中R1、R2和R3各自独立地是芳香族碳氢残基，Yn−是源自具有3个或更多碳原子的羧酸的阴离子，其中含有取代的氟原子，n为1或2，前提是R1、R2和R3各自不是具有取代基的苯基，该取代基位于邻位和/或间位），并且由该化合物和一种二硫酰二氮化合物组成的组合物被公开。使用该化合物或该化合物作为酸发生剂用于光刻胶会产生改善超细图案轮廓或减少超细图案侧壁不规则性的效果。该化合物还可用作阳离子光聚合引发剂。
• 9-Anthrylalkyl compounds, their preparation and their use
  申请人：Eka Nobel Aktiebolag

  公开号：EP0365495A2

  公开（公告）日：1990-04-25

  New 9-anthrylalkyl compounds having the general formula wherein R is hydrogen or an alkyl group, whereby, however, not more than one of the groups R is an alkyl group; R₁ is hydrogen, lower alkyl, halogen or nitro; n is an integer of from 1 to 7, whereby ,however, the total number of carbon atoms in the group -CHR-(CHR)n- does not exceed 8; and X is halogen, an azide group or a succinimidyl group. The new compounds are prepared from 9-anthrylalcohols which are reacted with a compound X-CO-X wherein X is a halogen, and then optionally with compounds giving azide or succinimidyl group. The compounds are used as derivatiza­tion reagents for separation and detection purposes. Intermediates for preparation of the above defined 9-anthrylalkyl compounds wherein one R is an alkyl group are 9-anthrylalcohols with the group -CHR-(CHR)n-OH, wherein one R is an alkyl group.

  通式如下的新型 9-蒽烷基化合物 其中，R 是氢或烷基，但是，R 中不超过一个基团是烷基；R₁ 是氢、低级烷基、卤素或硝基；n 是 1 到 7 的整数，但是，基团 -CHR-(CHR)n- 中的碳原子总数不超过 8；X 是卤素、叠氮基团或琥珀酰亚胺基团。 新化合物由 9-蒽醇制备而成，9-蒽醇先与化合物 X-CO-X 反应，其中 X 为卤素，然后再与含有叠氮基团或琥珀酰亚胺基团的化合物反应。这些化合物可用作衍生试剂，用于分离和检测。 制备上述定义的 9-蒽烷基化合物（其中一个 R 是烷基）的中间体是基团为 -CHR-(CHR)n-OH（其中一个 R 是烷基）的 9-蒽醇。
• A polymer utilized in water system and a method of treatment of water system
  申请人：KURITA WATER INDUSTRIES LTD.

  公开号：EP0485882A1

  公开（公告）日：1992-05-20

  Concentration of polymer in water system which is utilized for prevention of formation of scale and occurrence of corrosion is measured easily, accurately and promptly and controlled to the optimum concentration by a method comprising labelling of the polymer with a fluorescent substance, addition of the labelled polymer to the water system and measurement of the concentration of the fluorescent substance in the water system.

  聚合物在水系统中的浓度可用于防止水垢的形成和腐蚀的发生，测量方法简便、准确、迅速，并可控制在最佳浓度，该方法包括用荧光物质标记聚合物，将标记的聚合物加入水系统，并测量荧光物质在水系统中的浓度。
• Oligonucleotide-polyamide conjugates
  申请人：HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE

  公开号：EP0972779A2

  公开（公告）日：2000-01-19

  Oligonucleotide-polyamide conjugates of the formula X-L-Y, where X is a polyamide, Y is an oligonucleotide, and L is a linker which forms a covalent bond with the amino-terminus of the polyamide X and the 3' phosphate group of the oligonucleotide Y. Conjugates may be synthesized by assembling a polyamide on a solid support matrix, adding a suitable linker molecule, followed by synthesis of the oligonucleotide. Methods for detecting specific polynucleotides with oligonucleotide-polyamide conjugates are also described.

  式 X-L-Y 的寡核苷酸-聚酰胺共轭物，其中 X 是聚酰胺，Y 是寡核苷酸，L 是连接体，它与聚酰胺 X 的氨基末端和寡核苷酸 Y 的 3'磷酸基团形成共价键。可通过在固体支持基质上组装聚酰胺，加入合适的连接分子，然后合成寡核苷酸来合成共轭物。还介绍了用寡核苷酸-聚酰胺共轭物检测特定多核苷酸的方法。
• MOLECULAR MODULE
  申请人：The University of Tokyo

  公开号：EP2098538A1

  公开（公告）日：2009-09-09

  The present invention aims at providing a general-purpose experimental tool which specifically binds to a macromolecular substance that will be a receptor for a specific ligand such as drug, and is applicable throughout various processes to explore the nature of the macromolecular substance. In order to achieve this object, a molecular module has been developed which binds to a target compound and is used for purifying or labeling the target compound, wherein the molecular module has a rod-like spacer substance, an interacting substance that interacts with the target compound, a tag and a labeling substance, the interacting substance being positioned at one end of the rod-like spacer substance, and the tag and the labeling substance being positioned at the other end of the rod-like spacer substance.

  本发明的目的是提供一种通用的实验工具，它能专门与大分子物质结合，使其成为特定配体（如药物）的受体，并适用于探索大分子物质性质的各种过程。为了实现这一目标，我们开发了一种分子模块，它能与目标化合物结合，并用于纯化或标记目标化合物，其中分子模块具有杆状间隔物质、与目标化合物相互作用的相互作用物质、标签和标记物质，相互作用物质位于杆状间隔物质的一端，标签和标记物质位于杆状间隔物质的另一端。