6-Tert-butyl-7-methoxyquinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6-Tert-butyl-7-methoxyquinoline
• 英文别名: 6-tert-butyl-7-methoxyquinoline
• 化学式: C₁₄H₁₇NO
• 分子量: 215.29
• InChiKey: XUMPYJQDGVNUKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• THIADIAZOLE ANALOGS THEREOF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED-CONDITIONS
  申请人：AXFORD Jake

  公开号：US20140206661A1

  公开（公告）日：2014-07-24

  The present invention provides a compound of Formula (X) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

  本发明提供了一种公式（X）的化合物或其药用盐；一种制造本发明化合物的方法及其治疗用途。本发明进一步提供了一种药物活性剂的组合物和一种药物组合物。
• IL-2 conjugates and methods of use thereof
  申请人：Synthorx, Inc.

  公开号：US11077195B2

  公开（公告）日：2021-08-03

  Disclosed herein are compositions, kits, and methods comprising interleukin (IL) conjugates (e.g., IL-2 conjugates) useful for the treatment of one or more indications. Also described herein are pharmaceutical compositions and kits comprising one or more of the interleukin conjugates (e.g., IL-2 conjugates).

  本文公开了包含白细胞介素（IL）共轭物（如IL-2共轭物）的组合物、试剂盒和方法，可用于治疗一种或多种适应症。本文还描述了包含一种或多种白细胞介素共轭物（如 IL-2 共轭物）的药物组合物和试剂盒。
• IL-2 CONJUGATES AND METHODS OF USE THEREOF
  申请人：SYNTHORX, INC.

  公开号：US20200246467A1

  公开（公告）日：2020-08-06

  Disclosed herein are compositions, kits, and methods comprising interleukin (IL) conjugates (e.g., IL-2 conjugates) useful for the treatment of one or more indications. Also described herein are pharmaceutical compositions and kits comprising one or more of the interleukin conjugates (e.g., IL-2 conjugates).
• IL-2 Conjugates and Methods of Use Thereof
  申请人：Synthorx, Inc.

  公开号：US20200330601A1

  公开（公告）日：2020-10-22

  Disclosed herein are compositions, kits, and methods comprising interleukin (IL) conjugates (e.g., IL-2 conjugates) useful for the treatment of one or more indications. Also described herein are pharmaceutical compositions and kits comprising one or more of the interleukin conjugates (e.g., IL-2 conjugates).
• US9040712B2
  申请人：——

  公开号：US9040712B2

  公开（公告）日：2015-05-26