N,N-diethyl-4-[(3-methyl-1,3-benzothiazol-3-ium-2-yl)methyl]-1-phenyl-4H-quinolin-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N,N-diethyl-4-[(3-methyl-1,3-benzothiazol-3-ium-2-yl)methyl]-1-phenyl-4H-quinolin-2-amine
• 化学式: C28H30N3S+
• 分子量: 440.6
• InChiKey: FRVDVBKDWJNHHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  38.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• HAND-HELD WIRELESS PLATFORM AND OPTICS FOR MEASUREMENT OF DNA, RNA, MICRORNAS, AND OTHER MARKERS OF PATHOGENS, GENETIC DISEASES, AND CANCER
  申请人：BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY

  公开号：US20140211204A1

  公开（公告）日：2014-07-31

  The present invention provides compositions for making and methods of using a hand-held nucleic acid amplification device, comprising a disposable biochip with a series of sample wells, each sample well having a novel optical arrangement that includes a light-emitting diode (LED) and a single light capturing element (e.g. a photodiode) for quickly measuring light emissions from biological samples such as nucleic acid amplification reactions. Such a device can utilize isothermal amplification for obtaining detectable yields of amplified nucleic acid product in short time periods, for example, within seconds.